STRINGSTRING
Snas_5907 Snas_5907 Snas_0003 Snas_0003 Snas_0210 Snas_0210 Snas_0527 Snas_0527 Snas_0615 Snas_0615 iolG iolG Snas_0780 Snas_0780 Snas_1077 Snas_1077 guaB guaB Snas_1092 Snas_1092 Snas_1222 Snas_1222 Snas_1248 Snas_1248 Snas_1558 Snas_1558 Snas_1602 Snas_1602 Snas_1842 Snas_1842 Snas_1914 Snas_1914 Snas_2145 Snas_2145 Snas_2378 Snas_2378 zwf zwf Snas_2561 Snas_2561 Snas_2640 Snas_2640 Snas_2778 Snas_2778 zwf-2 zwf-2 Snas_3082 Snas_3082 Snas_3264 Snas_3264 Snas_3284 Snas_3284 Snas_3493 Snas_3493 Snas_3499 Snas_3499 Snas_3748 Snas_3748 Snas_3875 Snas_3875 Snas_3890 Snas_3890 Snas_3952 Snas_3952 Snas_3970 Snas_3970 hisD hisD Snas_4028 Snas_4028 Snas_4069 Snas_4069 Snas_4116 Snas_4116 Snas_4289 Snas_4289 Snas_4312 Snas_4312 ilvC ilvC Snas_4551 Snas_4551 Snas_4565 Snas_4565 Snas_4657 Snas_4657 Snas_4827 Snas_4827 Snas_4983 Snas_4983 gpsA gpsA aroE aroE dxr dxr Snas_5135 Snas_5135 Snas_5149 Snas_5149 Snas_5158 Snas_5158 Snas_5308 Snas_5308 Snas_5355 Snas_5355 Snas_5546 Snas_5546 murB murB Snas_5678 Snas_5678 Snas_5719 Snas_5719 Snas_5752 Snas_5752
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Snas_5907PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: scl:sce7905 hypothetical protein. (287 aa)
Snas_0003TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: mno:Mnod_7446 6-phosphogluconate dehydrogenase, decarboxylating. (292 aa)
Snas_0210PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mlo:mlr1136 alcohol dehydrogenase. (338 aa)
Snas_0527PFAM: aldo/keto reductase; KEGG: mxa:MXAN_0303 aldo/keto reductase family oxidoreductase. (335 aa)
Snas_0615Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
iolGOxidoreductase domain protein; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (334 aa)
Snas_0780IMP dehydrogenase family protein; KEGG: afw:Anae109_3133 inositol-5-monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; SMART: CBS domain containing protein. (478 aa)
Snas_1077PFAM: oxidoreductase domain protein; KEGG: ara:Arad_4620 oxidoreductase protein. (384 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (495 aa)
Snas_1092TIGRFAM: IMP dehydrogenase family protein; KEGG: cha:CHAB381_0908 inositol-5-monophosphate dehydrogenase. (352 aa)
Snas_1222KEGG: rpt:Rpal_4362 isocitrate dehydrogenase, NADP- dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
Snas_1248PFAM: NAD-dependent epimerase/dehydratase; dTDP-4- dehydrorhamnose reductase; polysaccharide biosynthesis protein CapD; Male sterility domain; short-chain dehydrogenase/reductase SDR; KEGG: ank:AnaeK_4428 dTDP-4-dehydrorhamnose reductase. (279 aa)
Snas_1558PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: afw:Anae109_2506 D-3-phosphoglycerate dehydrogenase. (324 aa)
Snas_1602PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: bur:Bcep18194_C6875 3-hydroxyacyl-CoA dehydrogenase. (342 aa)
Snas_1842PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: dal:Dalk_0054 3-hydroxybutyryl-CoA dehydrogenase. (283 aa)
Snas_1914KEGG: reu:Reut_C5899 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (352 aa)
Snas_2145PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: pol:Bpro_1286 alcohol dehydrogenase GroES- like. (346 aa)
Snas_2378PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: sfu:Sfum_1404 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (690 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (511 aa)
Snas_2561PFAM: aldo/keto reductase; KEGG: bam:Bamb_4035 aldo/keto reductase. (332 aa)
Snas_2640PFAM: bifunctional deaminase-reductase domain protein; KEGG: dia:Dtpsy_1834 bifunctional deaminase- reductase domain protein. (187 aa)
Snas_2778PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: scl:sce0475 alcohol dehydrogenase. (392 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (466 aa)
Snas_3082PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mca:MCA2968 D-isomer specific 2-hydroxyacid dehydrogenase family protein, putative. (317 aa)
Snas_3264KEGG: hso:HS_0925 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; Belongs to the PdxA family. (347 aa)
Snas_3284PFAM: aldo/keto reductase; KEGG: mrd:Mrad2831_0318 aldo/keto reductase. (319 aa)
Snas_34932-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (336 aa)
Snas_3499PFAM: oxidoreductase domain protein; KEGG: atc:AGR_L_3148 hypothetical protein. (366 aa)
Snas_3748PFAM: aldo/keto reductase; KEGG: gur:Gura_3526 aldo/keto reductase. (317 aa)
Snas_3875PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; KEGG: cak:Caul_5013 shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (327 aa)
Snas_3890PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: pmy:Pmen_2590 short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase. (711 aa)
Snas_3952KEGG: rfr:Rfer_3890 zinc-binding alcohol dehydrogenase. (372 aa)
Snas_3970KEGG: dac:Daci_3022 deaminase-reductase domain- containing protein. (186 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa)
Snas_4028PFAM: bifunctional deaminase-reductase domain protein; KEGG: afw:Anae109_2731 riboflavin biosynthesis protein RibD. (242 aa)
Snas_4069PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: rhi:NGR_b17460 phosphoglycerate dehydrogenase. (347 aa)
Snas_41162-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (308 aa)
Snas_4289PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sat:SYN_00088 3-isopropylmalate dehydrogenase. (346 aa)
Snas_4312KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein. (533 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
Snas_4551PFAM: bifunctional deaminase-reductase domain protein; KEGG: dal:Dalk_3312 riboflavin biosynthesis protein RibD. (215 aa)
Snas_4565Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme. (476 aa)
Snas_4657PFAM: oxidoreductase domain protein; Semialdehyde dehydrogenase NAD - binding; Oxidoreductase domain; KEGG: smt:Smal_1047 oxidoreductase domain protein. (366 aa)
Snas_4827KEGG: reu:Reut_C5899 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (349 aa)
Snas_4983PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: spe:Spro_2575 oxidoreductase domain- containing protein. (414 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; NADP oxidoreductase coenzyme F420-dependent; Ketopantoate reductase ApbA/PanE domain protein; KEGG: ade:Adeh_0396 glycerol-3-phosphate dehydrogenase (NAD(P)+). (331 aa)
aroEShikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (310 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (405 aa)
Snas_5135PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ret:RHE_CH00077 putative oxidoreducatse protein. (393 aa)
Snas_5149PFAM: oxidoreductase domain protein; homoserine dehydrogenase NAD-binding; Oxidoreductase domain; KEGG: mmw:Mmwyl1_3508 oxidoreductase domain- containing protein. (329 aa)
Snas_5158Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; UBA/THIF-type NAD/FAD binding protein; KEGG: tau:Tola_0213 malate dehydrogenase (oxaloacetate-decarboxylating). (386 aa)
Snas_5308PFAM: aldo/keto reductase; KEGG: afw:Anae109_2886 aldo/keto reductase. (327 aa)
Snas_5355PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: bmj:BMULJ_00680 D-lactate dehydrogenase. (319 aa)
Snas_5546PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: pca:Pcar_1451 homoserine dehydrogenase. (434 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (347 aa)
Snas_5678Nucleotide sugar dehydrogenase; KEGG: sit:TM1040_3775 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase. (474 aa)
Snas_5719PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KR domain protein; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; KEGG: hypothetical protein. (352 aa)
Snas_5752PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rhi:NGR_c15100 putative glycerate dehydrogenase. (333 aa)
Your Current Organism:
Stackebrandtia nassauensis
NCBI taxonomy Id: 446470
Other names: S. nassauensis DSM 44728, Stackebrandtia nassauensis DSM 44728, Stackebrandtia nassauensis str. DSM 44728, Stackebrandtia nassauensis strain DSM 44728
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