STRINGSTRING
DDB_G0295827 DDB_G0295827 arpB arpB arcA arcA arcB arcB arcC arcC arcD arcD arcE arcE act18 act18 act3 act3 act1 act1 frmC frmC cofB cofB acpA acpA acpB acpB AAC1 AAC1 nxnA nxnA corA corA tubA tubA tubB tubB dhcA dhcA coaA coaA rab7A rab7A arpC arpC cap cap fimA fimA aip1 aip1 dicA dicA myoE myoE DDB_G0278635 DDB_G0278635 DDB_G0275795 DDB_G0275795 DDB0192162 DDB0192162 DDB_G0293368 DDB_G0293368 DDB0191777 DDB0191777 dync1li1 dync1li1 DDB0219761 DDB0219761 DDB0184259 DDB0184259 FrpA FrpA DDB0183887 DDB0183887 DDB_G0291350 DDB_G0291350 DDB0183780 DDB0183780 dynF dynF dlrA dlrA DDB0219582 DDB0219582 rabO rabO DDB0219527 DDB0219527 DDB_G0289943 DDB_G0289943 act10 act10 DDB0188566 DDB0188566 DDB0219461 DDB0219461 act28 act28 act27 act27 act25 act25 act24 act24 arpA arpA DDB0188132 DDB0188132 hook hook DDB0187791 DDB0187791 DDB0187762 DDB0187762 Act33 Act33 arpH arpH rab7B rab7B zipA zipA act29 act29 DDB0186998 DDB0186998 DDB0218812 DDB0218812 DDB0186894 DDB0186894 dlcC dlcC dynB dynB saraf saraf dlcA dlcA Fia Fia PhaZ PhaZ NxnB NxnB DDB0185918 DDB0185918 DDB0185719 DDB0185719 DDB0185674 DDB0185674 DDB_G0283683 DDB_G0283683 arl8 arl8 cofE cofE DDB0204997 DDB0204997 DDB0204863 DDB0204863 DDB0204793 DDB0204793 DDB0218370 DDB0218370 DDB_G0282185 DDB_G0282185 DDB0204271 DDB0204271 DDB0204653 DDB0204653 DDB0204632 DDB0204632 kif7 kif7 DDB0204598 DDB0204598 DDB0204568 DDB0204568 DDB0205566 DDB0205566 kif3 kif3 DDB0218249 DDB0218249 DDB0206051 DDB0206051 dynA dynA dynD dynD DDB0206005 DDB0206005 DDB0205814 DDB0205814 DDB_G0279461 DDB_G0279461 dynE dynE DDB0205525 DDB0205525 FimC FimC DDB_G0278499 DDB_G0278499 DDB0205492 DDB0205492 DDB0205392 DDB0205392 DDB_G0278075 DDB_G0278075 DDB0217896 DDB0217896 DDB0217808 DDB0217808 DDB0217777 DDB0217777 DDB0202463 DDB0202463 DDB0202514 DDB0202514 act22 act22 act17 act17 DDB0217534 DDB0217534 kif9 kif9 cofD-1 cofD-1 DDB0202984 DDB0202984 DDB0217102 DDB0217102 abpE-1 abpE-1 DDB_G0272975 DDB_G0272975 DDB0216913 DDB0216913 WipA WipA DDB_G0270322 DDB_G0270322 FimD FimD DDB_G0270752 DDB_G0270752 DDB0190861 DDB0190861 act26 act26 DDB0190636 DDB0190636 DDB0190592 DDB0190592 DDB0190549 DDB0190549 DDB0190490 DDB0190490 Act32 Act32 abnB abnB DDB_G0269488 DDB_G0269488 Act31 Act31 corB corB DDB0216649 DDB0216649 ate1 ate1 act23 act23 DDB0189883 DDB0189883 DDB0189873 DDB0189873 DDB0189757 DDB0189757 DDB0189688 DDB0189688 DDB0189513 DDB0189513 forD forD DDB0169519 DDB0169519 DDB0168763 DDB0168763 DDB_G0277615 DDB_G0277615 nudE nudE DDB_G0272811 DDB_G0272811 twfA twfA DDB0167169 DDB0167169 dlcB dlcB DDB0169084 DDB0169084 DDB0217812 DDB0217812 cofF cofF DDB0167554 DDB0167554 gacF gacF kif5 kif5 cofC-1 cofC-1 wasA wasA kif1 kif1 dct dct myoK myoK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDB_G0295827Leucine-rich repeat-containing protein. (572 aa)
arpBActin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in [...] (392 aa)
arcAActin-related protein 2/3 complex subunit 1; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general [...] (369 aa)
arcBActin-related protein 2/3 complex subunit 2; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general [...] (293 aa)
arcCActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general [...] (174 aa)
arcDActin-related protein 2/3 complex subunit 4; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general [...] (169 aa)
arcEActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general [...] (138 aa)
act18Actin-18; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (380 aa)
act3Actin-3; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction; Belongs to the actin family. (376 aa)
act1Major actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction. (376 aa)
frmCFERM domain-containing protein C. (1489 aa)
cofBCofilin-1B; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity); Belongs to the actin-binding proteins ADF family. (137 aa)
acpAF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
acpBF-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (281 aa)
AAC1Leucine-rich repeat-containing protein AAC1. (797 aa)
nxnAAnnexin A7; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. (462 aa)
corACoronin-A; Required for normal motility. Participates in cytokinesis. (445 aa)
tubATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (457 aa)
tubBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa)
dhcADynein heavy chain, cytoplasmic; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP; Belongs to the dynein heavy chain family. (4730 aa)
coaACoactosin; Binds to F-actin in a calcium independent manner. Binds to the filaments along their length. (146 aa)
rab7ARas-related protein Rab-7A; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Involved in lipophagy, a cytosolic lipase-independent autophagic pathway (By similarity); Belongs to the small GTPase superfamily. Rab family. (203 aa)
arpCActin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in [...] (418 aa)
capAdenylyl cyclase-associated protein; May have a regulatory bifunctional role. Binds G-actin and PIP2. Involved in microfilament reorganization near the plasma membrane in a PIP2-regulated manner. (464 aa)
fimAFimbrin; Binds to actin. (610 aa)
aip1Actin-interacting protein 1; Implicated in both actin filament depolymerization and polymerization. May enhance chemotaxis by promoting cofilin-dependent actin assembly at cell leading edges. (597 aa)
dicACytoplasmic dynein 1 intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chain mediates the binding of dynein to dynactin. (654 aa)
myoEMyosin IE heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. May play a role in moving membranes relative to actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1005 aa)
DDB_G0278635Leucine-rich repeat-containing protein. (624 aa)
DDB_G0275795PH domain-containing protein DDB_G0275795. (808 aa)
DDB0192162Uncharacterized protein. (800 aa)
DDB_G0293368Uncharacterized protein. (41 aa)
DDB0191777DUF2013 domain-containing protein. (349 aa)
dync1li1Cytoplasmic dynein 1 light intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes (By similarity). (504 aa)
DDB0219761Uncharacterized protein. (1481 aa)
DDB0184259Arf-GAP domain-containing protein. (522 aa)
FrpAUncharacterized protein. (1096 aa)
DDB0183887Uncharacterized protein. (688 aa)
DDB_G0291350Probable serine/threonine-protein kinase DDB_G0291350; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (369 aa)
DDB0183780Uncharacterized protein. (1583 aa)
dynFDynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily. (189 aa)
dlrAUncharacterized protein. (818 aa)
DDB0219582Uncharacterized protein. (368 aa)
rabORas-related protein RabO. (218 aa)
DDB0219527Uncharacterized protein. (838 aa)
DDB_G0289943Protein CLEC16A homolog; Regulator of mitophagy. (1550 aa)
act10Actin-10; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (376 aa)
DDB0188566BRCT domain-containing protein. (1966 aa)
DDB0219461F-box domain-containing protein. (729 aa)
act28Putative actin-28; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (353 aa)
act27Putative actin-27; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (372 aa)
act25Putative actin-25; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (385 aa)
act24Putative actin-24; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (377 aa)
arpACentractin; Component of a multi-subunit complex, PPK2 (poly P kinase complex 2) involved in microtubule based vesicle motility. It is associated with the centrosome. PPK2 complex can synthesize a poly chain of hundreds of phosphate residues linked by ATP-like bonds. Belongs to the actin family. ARP1 subfamily. (383 aa)
DDB0188132Uncharacterized protein. (995 aa)
hookProtein hook homolog; Cytoskeletal linker protein involved in tethering membrane bound organelles to the cytoskeleton; Belongs to the hook family. (734 aa)
DDB0187791Protein phosphatase; Belongs to the PP2C family. (393 aa)
DDB0187762PARP catalytic domain-containing protein. (1082 aa)
Act33Uncharacterized protein; Belongs to the actin family. (414 aa)
arpHActin-related protein 10. (475 aa)
rab7BRas-related protein Rab-7B; Protein transport. Probably involved in vesicular traffic (By similarity). (197 aa)
zipAUncharacterized protein. (1024 aa)
act29Putative actin-29; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (387 aa)
DDB0186998Uncharacterized protein. (730 aa)
DDB0218812SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (1214 aa)
DDB0186894Uncharacterized protein. (630 aa)
dlcCDynein light chain roadblock. (97 aa)
dynBDynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. (430 aa)
sarafStore-operated calcium entry-associated regulatory factor; Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling; Belongs to the SARAF family. (320 aa)
dlcADynein light chain Tctex-type; Acts as a non-catalytic accessory component of a dynein complex; Belongs to the dynein light chain Tctex-type family. (111 aa)
FiaActin domain-containing protein. (944 aa)
PhaZUncharacterized protein. (340 aa)
NxnBUncharacterized protein. (487 aa)
DDB0185918PPM-type phosphatase domain-containing protein. (403 aa)
DDB0185719ADF-H domain-containing protein. (619 aa)
DDB0185674Uncharacterized protein. (394 aa)
DDB_G0283683Leucine-rich repeat-containing protein. (521 aa)
arl8ADP-ribosylation factor-like protein 8; Belongs to the small GTPase superfamily. Arf family. (185 aa)
cofECofilin-4; Controls actin polymerization and depolymerization. Belongs to the actin-binding proteins ADF family. (135 aa)
DDB0204997Calponin-homology (CH) domain-containing protein. (629 aa)
DDB0204863Uncharacterized protein. (552 aa)
DDB0204793Uncharacterized protein. (909 aa)
DDB0218370Uncharacterized protein. (584 aa)
DDB_G0282185RING zinc finger-containing protein. (790 aa)
DDB0204271Uncharacterized protein. (452 aa)
DDB0204653Uncharacterized protein. (396 aa)
DDB0204632WH2 domain-containing protein. (459 aa)
kif7Kinesin-related protein 7; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. May be involved in cell motility or cell differentiation during prestalk formation. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1255 aa)
DDB0204598Uncharacterized protein. (1389 aa)
DDB0204568Arf-GAP domain-containing protein. (608 aa)
DDB0205566Uncharacterized protein; Belongs to the peptidase S9B family. (803 aa)
kif3Kinesin-related protein 3; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. The maximal velocity in an inverted motility assay (moving microtubules on fixed motors) was 1.96 um/s. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily. (1193 aa)
DDB0218249Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (310 aa)
DDB0206051Uncharacterized protein. (1019 aa)
dynADynactin 150 kDa subunit. (1539 aa)
dynDDynactin 62 kDa subunit. (606 aa)
DDB0206005Uncharacterized protein. (1084 aa)
DDB0205814Uncharacterized protein. (617 aa)
DDB_G0279461Probable protein phosphatase DDB_G0279461. (1006 aa)
dynEDynactin subunit 5; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily. (198 aa)
DDB0205525Huntingtin associated protein-1-domain containing protein. (737 aa)
FimCUncharacterized protein. (1213 aa)
DDB_G0278499Protein phosphatase 2C. (307 aa)
DDB0205492Uncharacterized protein. (414 aa)
DDB0205392Uncharacterized protein. (996 aa)
DDB_G0278075UBIQUITIN_CONJUGAT_2 domain-containing protein. (232 aa)
DDB0217896UVR domain-containing protein. (729 aa)
DDB0217808Uncharacterized protein. (900 aa)
DDB0217777PH domain-containing protein. (597 aa)
DDB0202463Uncharacterized protein. (1385 aa)
DDB0202514F-box domain-containing protein. (843 aa)
act22Putative actin-22; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (376 aa)
act17Actin-17; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (374 aa)
DDB0217534Uncharacterized protein. (915 aa)
kif9Kinesin-related protein 9; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1222 aa)
cofD-1Cofilin-3; Controls actin polymerization and depolymerization. Belongs to the actin-binding proteins ADF family. (138 aa)
DDB0202984Uncharacterized protein. (558 aa)
DDB0217102SH3 domain-containing protein. (447 aa)
abpE-1Drebrin-like protein; Actin-binding adapter protein. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G- actin. Controls pseudopodium number and motility in early stages of chemotactic aggregation. (481 aa)
DDB_G0272975BTB domain-containing protein. (692 aa)
DDB0216913Uncharacterized protein. (471 aa)
WipAWH2 domain-containing protein. (197 aa)
DDB_G0270322Leucine-rich repeat-containing protein. (720 aa)
FimDUncharacterized protein. (1714 aa)
DDB_G0270752Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. (184 aa)
DDB0190861PPM-type phosphatase domain-containing protein. (1359 aa)
act26Putative actin-26; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (375 aa)
DDB0190636SH3 domain-containing protein. (364 aa)
DDB0190592Calponin-homology (CH) domain-containing protein. (446 aa)
DDB0190549Uncharacterized protein. (1032 aa)
DDB0190490Uncharacterized protein. (305 aa)
Act32Uncharacterized protein; Belongs to the actin family. (392 aa)
abnBActobindin-B/C; Is able to bind two actin monomers at high concentrations of G-actin. Inhibits actin polymerization by sequestering G-actin and stabilizing actin dimers (By similarity). (90 aa)
DDB_G0269488Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (128 aa)
Act31Uncharacterized protein; Belongs to the actin family. (355 aa)
corBCoronin-B; Involved in phagocytosis and cell motility. Binds to actin filaments and protects them against depolymerization. Belongs to the WD repeat coronin family. (962 aa)
DDB0216649Rab-GAP TBC domain-containing protein. (831 aa)
ate1Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity); Belongs to the R-transferase family. (629 aa)
act23Putative actin-23; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity); Belongs to the actin family. (358 aa)
DDB0189883Uncharacterized protein. (529 aa)
DDB0189873Uncharacterized protein. (848 aa)
DDB0189757Uncharacterized protein. (477 aa)
DDB0189688Calponin-homology (CH) domain-containing protein. (954 aa)
DDB0189513Peptidase_S9 domain-containing protein. (777 aa)
forDFormin-D; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1214 aa)
DDB0169519N-acetyltransferase domain-containing protein. (204 aa)
DDB0168763Uncharacterized protein. (540 aa)
DDB_G0277615Uncharacterized protein. (522 aa)
nudELis-interacting protein. (398 aa)
DDB_G0272811WASP-related protein. (583 aa)
twfATwinfilin; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). (335 aa)
DDB0167169Uncharacterized protein. (799 aa)
dlcBDynein light chain, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex; Belongs to the dynein light chain family. (91 aa)
DDB0169084Uncharacterized protein. (1210 aa)
DDB0217812Uncharacterized protein. (664 aa)
cofFCofilin-5; Controls actin polymerization and depolymerization. Belongs to the actin-binding proteins ADF family. (122 aa)
DDB0167554Uncharacterized protein. (880 aa)
gacFRho GTPase-activating protein gacF; Rho GTPase-activating protein involved in the signal transduction pathway. (1140 aa)
kif5Kinesin-related protein 5; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end (By similarity). May connect microtubules to actin filaments. Associates with actin-based structures in cells and is likely involved in the organization of actin cytoskeletons in such structures; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily. (990 aa)
cofC-1Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Cofilin-2 may play a distinct role from that of cofilin-1 in destabilization of the actin cytoskeleton during Dictyostelium development. (143 aa)
wasAWiscott-Aldrich syndrome protein. (399 aa)
kif1Kinesin-related protein 1; Microtubule-associated force-producing protein that plays a role in organelle transport. Its motor activity is directed toward the microtubule's plus end. Transports cytoplasmic vesicles and particularly phosphatidylinositol 4,5-bisphosphate-containing liposomes along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily. (2205 aa)
dctDynacortin. (354 aa)
myoKMyosin-K heavy chain; Myosins are actin-based motor molecules with ATPase activity. Involved in phagocytosis and motility, and in the maintenance and dynamics of cell cortex; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (858 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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