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| | rabif | Mss4-like family protein. (163 aa) |
| | arfA | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. (182 aa) |
| | darA | Darlin; Part of a signaling pathway that initiates the aggregation and leads to the formation of aggregation centers or streams. Not essential for cytokinesis, pinocytosis or phagocytosis. Not essential for development, except in starvation-induced aggregation. Belongs to the RAP1GDS1 family. (766 aa) |
| | racF1 | Rho-related protein racF1; Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes. (193 aa) |
| | cofA | Cofilin-1A; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity); Belongs to the actin-binding proteins ADF family. (137 aa) |
| | sevA | Severin; Severin blocks the ends of F-actin and causes the fragmentation and depolymerization of actin filaments in a Ca(2+) dependent manner; Belongs to the villin/gelsolin family. (362 aa) |
| | proA | Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. (126 aa) |
| | proB | Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. (124 aa) |
| | rac1A | Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family. (194 aa) |
| | rac1B | Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles. (194 aa) |
| | rac1C | Rho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles. (193 aa) |
| | racA | Rho-related protein racA. (598 aa) |
| | racB | Rho-related protein racB; Belongs to the small GTPase superfamily. Rho family. (195 aa) |
| | racC | Rho-related protein racC; Belongs to the small GTPase superfamily. Rho family. (192 aa) |
| | racD | Rho-related protein racD; Belongs to the small GTPase superfamily. Rho family. (254 aa) |
| | racQ | Rho GTPase. (185 aa) |
| | racE | Rho-related protein racE; Specifically required for cytokinesis; Belongs to the small GTPase superfamily. Rho family. (223 aa) |
| | lrrA | Leucine-rich repeat protein lrrA; Involved in cytoskeleton remodeling, which is needed for normal chemotactic aggregation and efficient cell sorting during multicellular morphogenesis. (510 aa) |
| | ZizB | Uncharacterized protein; Belongs to the DOCK family. (2147 aa) |
| | forJ | Formin-J; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (2546 aa) |
| | noxC | Superoxide-generating NADPH oxidase heavy chain subunit C; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (1142 aa) |
| | gefK | Ras guanine nucleotide exchange factor K; Promotes the exchange of Ras-bound GDP by GTP. (1557 aa) |
| | racM | Rho-related protein racM. (189 aa) |
| | DDB0187665 | Uncharacterized protein. (1447 aa) |
| | talB | Talin-B; Actin-binding protein required for multicellular morphogenesis. Substrate of pkgB and/or pkbA. (2614 aa) |
| | forC | Formin-C; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1158 aa) |
| | DDB_G0286543 | RUN domain-containing protein. (1361 aa) |
| | ctnnA | Probable vinculin; Involved in cell adhesion. Thought to play an important role in cytokinesis B, probably by providing substrate adhesion and traction forces. Required to organize and polarize the tip epithelium during cytokinesis. Required for the normal distribution of myosin in the tip epithelium. Involved in the localization of ctxA, ctxB, dcsA, exoc6 and rgaA. Thought to form a complex with ctxA, ctxB, and rgaA which regulates myosin accumulation to the apical plasma membrane. Belongs to the vinculin/alpha-catenin family. (842 aa) |
| | forH | Formin-H; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. Important for cell migration and formation, elongation and maintenance of filopodia. Specifically controls filopodial dynamics by regulating actin turnover at the barbed ends of actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1087 aa) |
| | RacP | Rho GTPase. (376 aa) |
| | scrA | Protein SCAR; Involved in regulation of actin and microtubule organization. Regulates phagocytosis and macropinocytosis. Belongs to the SCAR/WAVE family. (443 aa) |
| | forI | Formin-I; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (935 aa) |
| | VilD | HP domain-containing protein. (1775 aa) |
| | GxcF | DH domain-containing protein. (932 aa) |
| | forB | Formin-B; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1126 aa) |
| | forA | Formin-A; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1218 aa) |
| | brk1 | Protein BRICK1; Involved in regulation of actin and microtubule organization. Belongs to the BRK1 family. (68 aa) |
| | culC-2 | Culmination specific protein 37D. (351 aa) |
| | racN | Rho-related protein racN. (219 aa) |
| | racO | Rho-related protein racO. (276 aa) |
| | DDB_G0271356 | LIM domain-containing protein DDB_G0271356. (186 aa) |
| | ZizD | Uncharacterized protein; Belongs to the DOCK family. (2162 aa) |
| | gefV | Ras guanine nucleotide exchange factor V; Promotes the exchange of Ras-bound GDP by GTP. (1982 aa) |
| | abiA | Abl interactor homolog; Involved in regulation of actin and microtubule organization. Required for proper cytokinesis; Belongs to the ABI family. (332 aa) |
| | pakC | Serine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. (477 aa) |
| | forF | Formin-F; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1220 aa) |
| | forE | Formin-E; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1561 aa) |
| | vasp | Protein VASP homolog; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as lamellipodial and filopodial dynamics in migrating cells. Plays a crucial role in filopodia formation, cell-substratum adhesion, and proper chemotaxis. Nucleates and bundles actin filaments. When complexed with fotH in filopodial tips, may support formin- mediated filament elongation by bundling nascent actin filaments. Belongs to the Ena/VASP family. (380 aa) |
| | poxA | Peroxinectin A; Belongs to the peroxidase family. (531 aa) |
| | pirA | Protein pirA; Involved in regulation of actin and microtubule organization. (1336 aa) |
| | EnlA | Fimbrin. (1503 aa) |
| | ncfA | NADPH oxidase activator; May function as an activator of NOX1, a superoxide-producing NADPH oxidase. (604 aa) |
| | cybA | Superoxide-generating NADPH oxidase light chain subunit; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. (118 aa) |
| | pakB | Serine/threonine-protein kinase pakB; Regulator of the myosin I component of the cytoskeleton: required for regulation of cytokinesis, phagocytosis and pinocytosis. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (852 aa) |
| | napA | Nck-associated protein 1 homolog; Involved in regulation of actin and microtubule organization. Involved in cell adhesion. (1160 aa) |
| | noxB | Superoxide-generating NADPH oxidase heavy chain subunit B; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (698 aa) |
| | ZizA | Uncharacterized protein; Belongs to the DOCK family. (2284 aa) |
| | dst1 | Serine/threonine-protein kinase dst1. (737 aa) |
| | paxB | Paxillin-B; Required for cell-substrate adhesion, cell sorting, slug migration, and cell differentiation. May function upstream of limB. (569 aa) |
| | gefS | Ras guanine nucleotide exchange factor S; Promotes the exchange of Ras-bound GDP by GTP. (1043 aa) |
| | proC | Profilin-3; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity). (126 aa) |
| | rdiB | Putative rho GDP-dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. (152 aa) |
| | rdiA | Putative rho GDP-dissociation inhibitor 1; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (By similarity). Regulates the Rac-dependent signaling pathways controlling cytokinesis, actin reorganization and the contractile vacuole. Required for efficient accumulation of cap at the cell cortex. (197 aa) |
| | racL | Rho-related protein racL. (196 aa) |
| | racJ | Rho-related protein racJ. (205 aa) |
| | racI | Rho-related protein racI. (205 aa) |
| | racH | Rho-related protein racH. (200 aa) |
| | racG | Rho-related protein racG. (201 aa) |
| | racF2 | Rho-related protein racF2. (193 aa) |
| | noxA | Superoxide-generating NADPH oxidase heavy chain subunit A; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (517 aa) |
