STRINGSTRING
rac1A rac1A rac1B rac1B racB racB pakC pakC pakB pakB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rac1ARho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family. (194 aa)
rac1BRho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles. (194 aa)
racBRho-related protein racB; Belongs to the small GTPase superfamily. Rho family. (195 aa)
pakCSerine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. (477 aa)
pakBSerine/threonine-protein kinase pakB; Regulator of the myosin I component of the cytoskeleton: required for regulation of cytokinesis, phagocytosis and pinocytosis. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (852 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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