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| | DDB_G0295717 | RabGAP/TBC domain-containing protein. (821 aa) |
| | rasD | Ras-like protein rasD; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (187 aa) |
| | rasG | Ras-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | splA | Dual specificity protein kinase splA; Essential for spore differentiation; Belongs to the protein kinase superfamily. TKL Tyr protein kinase family. (2410 aa) |
| | splB | Dual specificity protein kinase splB. (1155 aa) |
| | rapA | Ras-related protein rapA; G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis. May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions. Overexpressing cells generate alterations in cell shape and contractile responses. Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells. (186 aa) |
| | pkgB | Protein kinase 2; Required for morphogenesis during multicellular development. Phosphorylates talB, gefN, gefS, PI4P 5-kinase and gacQ. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa) |
| | rasB | Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (197 aa) |
| | rasC | Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | rasS | Ras-like protein rasS; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (194 aa) |
| | erkA | Extracellular signal-regulated kinase 1; Kinase involved in a signal transduction pathway. (529 aa) |
| | DDB_G0267566 | Probable serine/threonine-protein kinase DDB_G0267566; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (844 aa) |
| | DDB_G0293786 | Ras GTPase. (277 aa) |
| | dyrk2 | Probable serine/threonine-protein kinase dyrk2. (915 aa) |
| | DDB0191864 | PH domain-containing protein. (652 aa) |
| | kxcB | Kinase and exchange factor for Rac B. (1125 aa) |
| | DDB_G0293184 | Probable inactive serine/threonine-protein kinase DDB_G0293184. (1186 aa) |
| | DDB0191668 | Uncharacterized protein. (610 aa) |
| | mrkA | Probable serine/threonine-protein kinase MARK-A; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. (1060 aa) |
| | DDB_G0291516 | Probable serine/threonine-protein kinase DDB_G0291516. (965 aa) |
| | DDB_G0291510 | GTPase-activating protein DDB_G0291510. (1031 aa) |
| | rsmL | Rab GTPase. (203 aa) |
| | DDB0188839 | Peptidase C50 domain-containing protein. (2444 aa) |
| | GefAA | Uncharacterized protein. (1371 aa) |
| | Nek4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (498 aa) |
| | DDB0188227 | Uncharacterized protein. (1589 aa) |
| | DDB_G0288147 | Probable serine/threonine-protein kinase DDB_G0288147; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. (1347 aa) |
| | DDB0187664 | Uncharacterized protein. (542 aa) |
| | DDB0187261 | Uncharacterized protein. (1836 aa) |
| | DDB_G0286627 | Probable serine/threonine-protein kinase DDB_G0286627; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. (671 aa) |
| | DDB0218808 | Phorbol-ester/DAG-type domain-containing protein. (1649 aa) |
| | DDB0186876 | Uncharacterized protein. (756 aa) |
| | DDB0186499 | Uncharacterized protein. (746 aa) |
| | DDB0218708 | Uncharacterized protein. (920 aa) |
| | gefA | Ras guanine nucleotide exchange factor A; Ras-bound GDP/GTP exchange factor required for normal activation of adenylyl cyclase. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. (605 aa) |
| | DDB0185880 | Ras-GAP domain-containing protein. (1056 aa) |
| | nrde2 | Nuclear exosome regulator NRDE2; Protein of the nuclear speckles that regulates RNA exosomal degradation; Belongs to the NRDE2 family. (1320 aa) |
| | phg2 | Serine/threonine-protein kinase phg2; Serine/threonine kinase regulating cell substrate adhesion, phagocytosis, motility, chemotaxis, and actin cytoskeleton organization. It is a downstream component of Rap1-regulated adhesion, and it is a regulator of myosin II phosphorylation. It is also a negative regulator of development initiation. (1387 aa) |
| | rsmA | Small GTPase. (219 aa) |
| | DDB_G0283417 | Probable dual specificity protein phosphatase DDB_G0283417; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (230 aa) |
| | DDB_G0283337 | Probable serine/threonine-protein kinase DDB_G0283337; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1128 aa) |
| | DDB0185273 | Ras-GAP domain-containing protein. (608 aa) |
| | gbpD | Cyclic GMP-binding protein D; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Induces the formation of substrate-attached pseudopodia, that leads to increased adhesion and thereby negatively influencing cell speed and polarity. (1312 aa) |
| | DDB_G0282777 | Probable serine/threonine-protein kinase DDB_G0282777; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (639 aa) |
| | DDB_G0282417 | Probable serine/threonine-protein kinase DDB_G0282417; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (528 aa) |
| | DDB0205121 | Uncharacterized protein. (464 aa) |
| | mrkC | Probable serine/threonine-protein kinase MARK-C; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. (773 aa) |
| | gefP | Ras guanine nucleotide exchange factor P; Promotes the exchange of Ras-bound GDP by GTP. (1502 aa) |
| | rsmB | Small GTPase. (260 aa) |
| | DDB0205208 | Uncharacterized protein. (147 aa) |
| | DDB_G0280437 | Ras GTPase. (298 aa) |
| | DDB0206508 | Uncharacterized protein. (1084 aa) |
| | GflD | Ras-GEF domain-containing protein. (1765 aa) |
| | gacN | Rho GTPase-activating protein gacN; Rho GTPase-activating protein involved in the signal transduction pathway. (611 aa) |
| | ngap | Probable Ras GTPase-activating-like protein ngap; May function as a Ras GTPase-activating protein. (877 aa) |
| | rsmC | Small GTPase. (240 aa) |
| | rsmK | Small GTPase. (195 aa) |
| | DDB_G0277071 | Probable serine/threonine-protein kinase DDB_G0277071. (2454 aa) |
| | DDB_G0276181 | Probable serine/threonine-protein kinase DDB_G0276181; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. (1555 aa) |
| | gefY | Ras guanine nucleotide exchange factor Y; Promotes the exchange of Ras-bound GDP by GTP. (1508 aa) |
| | fnkE | Probable serine/threonine-protein kinase fnkE. (1321 aa) |
| | DDB0202560 | Rab-GAP TBC domain-containing protein. (702 aa) |
| | ZizC | Uncharacterized protein; Belongs to the DOCK family. (2621 aa) |
| | DDB_G0273199 | Probable rhodanese domain-containing dual specificity protein phosphatase; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (476 aa) |
| | DDB_G0272254 | Probable serine/threonine-protein kinase DDB_G0272254. (1331 aa) |
| | DDB_G0271806 | PH and Rap-GAP domain-containing protein DDB_G0271806. (1167 aa) |
| | DDB_G0271350 | Probable dual specificity protein phosphatase DDB_G0271350; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (275 aa) |
| | DDB0190874 | Uncharacterized protein. (687 aa) |
| | rasZ | Ras-like protein rasZ; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (214 aa) |
| | rasU | Ras-like protein rasU; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (213 aa) |
| | rasY | Ras-like protein rasY; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa) |
| | rasX | Ras-like protein rasX; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (213 aa) |
| | rasV | Ras-like protein rasV; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (229 aa) |
| | rasW | Ras-like protein rasW; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa) |
| | DDB_G0269404 | Probable dual specificity protein phosphatase DDB_G0269404; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (212 aa) |
| | gefX | RasGEF domain-containing serine/threonine-protein kinase X; Promotes the exchange of Ras-bound GDP by GTP; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. (960 aa) |
| | DDB0190084 | Uncharacterized protein. (2673 aa) |
| | fnkB | Probable serine/threonine-protein kinase fnkB. (530 aa) |
| | GxcD | Uncharacterized protein. (1063 aa) |
| | roco7 | Probable serine/threonine-protein kinase roco7; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. (2615 aa) |
| | roco9 | Probable serine/threonine-protein kinase roco9; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. (3365 aa) |
| | rapgap1 | RapA guanosine triphosphatase-activating protein 1; Mediates the deactivation of rap1 and plays an important role in spatially and temporally regulating cell adhesion and chemotaxis by controlling attachment disassembly in the leading edge through the regulation of myosin II assembly and disassembly. Overexpression leads to defective chemotaxis. (1055 aa) |
| | dyrk1 | Probable serine/threonine-protein kinase dyrk1. (836 aa) |
| | fnkA | Probable serine/threonine-protein kinase fnkA. (793 aa) |
| | DDB0217806 | Rap-GAP domain-containing protein. (855 aa) |
| | gefQ | Ras guanine nucleotide exchange factor Q; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Seems to play a role in chemotaxis. (1298 aa) |
| | rapB | Ras-related protein rapB. (205 aa) |
| | gefJ | Ras guanine nucleotide exchange factor J; Promotes the exchange of Ras-bound GDP by GTP. (812 aa) |
| | gefE | Ras guanine nucleotide exchange factor E; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Seems to play a role in chemotaxis. (1037 aa) |
| | gefD | Ras guanine nucleotide exchange factor D; Promotes the exchange of Ras-bound GDP by GTP. (668 aa) |
| | gefC | Ras guanine nucleotide exchange factor C; Promotes the exchange of Ras-bound GDP by GTP. (1457 aa) |
| | gefB | Ras guanine nucleotide exchange factor B; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Involved in phagocytosis, fluid-phase endocytosis, regulation of macropinocytosis and control of cell movement. (1529 aa) |
| | gbpC | Cyclic GMP-binding protein C; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Required for cyclic GMP-mediated chemotaxis, polarity. Plays a key role in cyclic AMP-induced myosin II translocation to the cortex. Also involved in the phosphorylation of mlkA and mlcR, either directly or via an intermediate kinase. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. (2631 aa) |
| | gefR | Ras guanine nucleotide exchange factor R; Promotes the exchange of Ras-bound GDP by GTP. May also play a role in the activation of rasG. (1721 aa) |
| | gefM | Ras guanine nucleotide exchange factor M; Promotes the exchange of Ras-bound GDP by GTP. (929 aa) |
| | DDB0167574 | Ras-GAP domain-containing protein. (1728 aa) |
| | sepA | Serine/threonine-protein kinase sepA; Serine/threonine-protein kinase involved in the spatial and temporal control system organizing cortical activities in mitotic and postmitotic cells. (1167 aa) |
| | DDB0168530 | Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (560 aa) |
