29 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pikA	Phosphatidylinositol 3-kinase 1. (1571 aa)
	pikB	Phosphatidylinositol 3-kinase 2. (1857 aa)
	pikC	Phosphatidylinositol 3-kinase 3. (1697 aa)
	DDB_G0288731	GRAM domain-containing protein. (1227 aa)
	DDB0191855	Myotubularin phosphatase domain-containing protein. (1192 aa)
	Dd5P3	Inositol 5-phosphatase. (1379 aa)
	DDB_G0292252	Putative protein DDB_G0292252. (1256 aa)
	DDB0219722	PIPK domain-containing protein. (944 aa)
	DDB_G0290005	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. (1324 aa)
	DDB0219484	Uncharacterized protein. (922 aa)
	DDB_G0286115	Phosphatidylinositol-4-phosphate 5-kinase family protein. (1271 aa)
	DDB0186027	Myotubularin phosphatase domain-containing protein. (1028 aa)
	Dd5P2	Inositol 5-phosphatase. (1800 aa)
	PikG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1671 aa)
	DDB0204242	Myotubularin phosphatase domain-containing protein. (1343 aa)
	DDB_G0280377	Uncharacterized protein. (784 aa)
	DDB0205364	Myotubularin phosphatase domain-containing protein. (1002 aa)
	DDB0203449	Uncharacterized protein. (822 aa)
	DDB_G0272638	Phosphatidylinositol-4-phosphate 5-kinase family protein. (1079 aa)
	DDB0216866	Myotubularin phosphatase domain-containing protein. (1738 aa)
	DDB0190271	Uncharacterized protein. (1292 aa)
	pats1	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton. (3184 aa)
	DDB0190143	Uncharacterized protein. (1214 aa)
	PikF	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1382 aa)
	DDB_G0267588	Probable phosphatidylinositol phosphate kinase DDB_G0267588; May be involved in signaling events that underlie chemotaxis via the chemoattractant-mediated pkgB phosphorylation. (719 aa)
	PIPkinA	Uncharacterized protein. (1589 aa)
	rpkA	RpkA. (828 aa)
	Dd5P4	Inositol 5-phosphatase 4. (787 aa)
	pteN	3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] (533 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0186027	DDB0190143	Q54PL3	Q55EE1	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.472
DDB0186027	DDB0190271	Q54PL3	Q55E04	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.470
DDB0186027	DDB0191855	Q54PL3	Q54C52	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.523
DDB0186027	DDB0204242	Q54PL3	Q54TD5	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB0205364	Q54PL3	Q54YC2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.502
DDB0186027	DDB0216866	Q54PL3	Q55AZ2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB0219484	Q54PL3	Q54H00	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.400
DDB0186027	DDB_G0288731	Q54PL3	Q1ZXD2	Myotubularin phosphatase domain-containing protein.	GRAM domain-containing protein.	0.497
DDB0186027	DDB_G0290005	Q54PL3	Q54GQ1	Myotubularin phosphatase domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.518
DDB0186027	Dd5P3	Q54PL3	Q54D97	Myotubularin phosphatase domain-containing protein.	Inositol 5-phosphatase.	0.434
DDB0186027	pats1	Q54PL3	Q55E58	Myotubularin phosphatase domain-containing protein.	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton.	0.400
DDB0190143	DDB0186027	Q55EE1	Q54PL3	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.472
DDB0190143	DDB0190271	Q55EE1	Q55E04	Uncharacterized protein.	Uncharacterized protein.	0.426
DDB0190143	DDB0191855	Q55EE1	Q54C52	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.471
DDB0190143	DDB0204242	Q55EE1	Q54TD5	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.487
DDB0190143	DDB0205364	Q55EE1	Q54YC2	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.461
DDB0190143	DDB0216866	Q55EE1	Q55AZ2	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.472
DDB0190143	DDB0219484	Q55EE1	Q54H00	Uncharacterized protein.	Uncharacterized protein.	0.405
DDB0190143	DDB_G0288731	Q55EE1	Q1ZXD2	Uncharacterized protein.	GRAM domain-containing protein.	0.473
DDB0190143	DDB_G0290005	Q55EE1	Q54GQ1	Uncharacterized protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.484