17 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pikA	Phosphatidylinositol 3-kinase 1. (1571 aa)
	pikB	Phosphatidylinositol 3-kinase 2. (1857 aa)
	pikC	Phosphatidylinositol 3-kinase 3. (1697 aa)
	pikE	Phosphatidylinositol 3-kinase VPS34-like. (816 aa)
	DDB_G0288731	GRAM domain-containing protein. (1227 aa)
	DDB0191855	Myotubularin phosphatase domain-containing protein. (1192 aa)
	DDB_G0290005	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. (1324 aa)
	DDB0186027	Myotubularin phosphatase domain-containing protein. (1028 aa)
	vps15	Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1966 aa)
	PikG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1671 aa)
	DDB0204242	Myotubularin phosphatase domain-containing protein. (1343 aa)
	DDB0205364	Myotubularin phosphatase domain-containing protein. (1002 aa)
	DDB0216866	Myotubularin phosphatase domain-containing protein. (1738 aa)
	DDB0190271	Uncharacterized protein. (1292 aa)
	pats1	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton. (3184 aa)
	DDB0190143	Uncharacterized protein. (1214 aa)
	PikF	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1382 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0186027	DDB0190143	Q54PL3	Q55EE1	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.472
DDB0186027	DDB0190271	Q54PL3	Q55E04	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.470
DDB0186027	DDB0191855	Q54PL3	Q54C52	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.523
DDB0186027	DDB0204242	Q54PL3	Q54TD5	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB0205364	Q54PL3	Q54YC2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.502
DDB0186027	DDB0216866	Q54PL3	Q55AZ2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB_G0288731	Q54PL3	Q1ZXD2	Myotubularin phosphatase domain-containing protein.	GRAM domain-containing protein.	0.497
DDB0186027	DDB_G0290005	Q54PL3	Q54GQ1	Myotubularin phosphatase domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.518
DDB0186027	pats1	Q54PL3	Q55E58	Myotubularin phosphatase domain-containing protein.	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton.	0.400
DDB0190143	DDB0186027	Q55EE1	Q54PL3	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.472
DDB0190143	DDB0190271	Q55EE1	Q55E04	Uncharacterized protein.	Uncharacterized protein.	0.426
DDB0190143	DDB0191855	Q55EE1	Q54C52	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.471
DDB0190143	DDB0204242	Q55EE1	Q54TD5	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.487
DDB0190143	DDB0205364	Q55EE1	Q54YC2	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.461
DDB0190143	DDB0216866	Q55EE1	Q55AZ2	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.472
DDB0190143	DDB_G0288731	Q55EE1	Q1ZXD2	Uncharacterized protein.	GRAM domain-containing protein.	0.473
DDB0190143	DDB_G0290005	Q55EE1	Q54GQ1	Uncharacterized protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.484
DDB0190143	pats1	Q55EE1	Q55E58	Uncharacterized protein.	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton.	0.400
DDB0190271	DDB0186027	Q55E04	Q54PL3	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.470
DDB0190271	DDB0190143	Q55E04	Q55EE1	Uncharacterized protein.	Uncharacterized protein.	0.426