Your Input: | |
| | gapA | Ras GTPase-activating-like protein gapA; Part of signaling pathway that is required for completion of cytokinesis. gapA and rgaA control cortexillin localization to the cleavage furrow and hence may be involved in cleavage of the midbody in the final stage of cytokinesis by regulating the actin cytoskeleton. Forms a complex by linking activated rac1A to ctxA in the absence of rgaA. Assembly of this complex is necessary for the recruitment of cortexillin to the midzone of the dividing cell. (860 aa) |
| | gpaA | Guanine nucleotide-binding protein alpha-1 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. (356 aa) |
| | rac1A | Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family. (194 aa) |
| | rab7A | Ras-related protein Rab-7A; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Involved in lipophagy, a cytosolic lipase-independent autophagic pathway (By similarity); Belongs to the small GTPase superfamily. Rab family. (203 aa) |
| | gxcZ | RhoGEF domain-containing protein. (1028 aa) |
| | DDB_G0292160 | Uncharacterized protein DDB_G0292160. (174 aa) |
| | gacM | Rho GTPase-activating protein gacM; Rho GTPase-activating protein involved in the signal transduction pathway. (896 aa) |
| | gxcDD | Guanine exchange factor for Rac 30; GTPase-activating protein for Rac involved in streaming and development. (1632 aa) |
| | gacV | Rho GTPase-activating protein gacV; Rho GTPase-activating protein involved in the signal transduction pathway. (520 aa) |
| | GxcO | Uncharacterized protein. (829 aa) |
| | GxcKK | Uncharacterized protein. (667 aa) |
| | GxcY | Uncharacterized protein. (1076 aa) |
| | ZizB | Uncharacterized protein; Belongs to the DOCK family. (2147 aa) |
| | docA | Uncharacterized protein; Belongs to the DOCK family. (2221 aa) |
| | DocC | DHR-2 domain-containing protein; Belongs to the DOCK family. (1736 aa) |
| | racGAP | Uncharacterized protein. (1350 aa) |
| | GxcU | Uncharacterized protein. (986 aa) |
| | gacEE | Rho GTPase-activating protein gacEE; Rho GTPase-activating protein involved in the signal transduction pathway. (570 aa) |
| | noxC | Superoxide-generating NADPH oxidase heavy chain subunit C; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (1142 aa) |
| | GxcK | Uncharacterized protein. (963 aa) |
| | gacJJ | Rho GTPase-activating protein gacJJ; Rho GTPase-activating protein involved in the signal transduction pathway. (873 aa) |
| | GxcHH | Uncharacterized protein. (954 aa) |
| | DDB0188882 | Uncharacterized protein. (693 aa) |
| | sybB | Synaptobrevin-B; Involved in the targeting and/or fusion of transport vesicles to their target membrane; Belongs to the synaptobrevin family. (101 aa) |
| | GxcL | DH domain-containing protein. (805 aa) |
| | GefAA | Uncharacterized protein. (1371 aa) |
| | DDB0188240 | Uncharacterized protein. (271 aa) |
| | DDB0188227 | Uncharacterized protein. (1589 aa) |
| | gxcH | RhoGEF domain-containing protein gxcH; GTPase-activating protein. (928 aa) |
| | DDB0187665 | Uncharacterized protein. (1447 aa) |
| | rgaA | Ras GTPase-activating-like protein rgaA; Part of signaling pathway that is required for completion of cytokinesis. gapA and rgaA control cortexillin localization to the cleavage furrow and hence may be involved in cleavage of the midbody in the final stage of cytokinesis by regulating the actin cytoskeleton. Forms a complex by linking activated rac1A to ctxA. Assembly of this complex is necessary for the recruitment of cortexillin to the midzone of a dividing cell. Overexpression leads to the suppression of the formation of cellular projections containing F-actin and to a defect in cyt [...] (822 aa) |
| | DDB_G0286543 | RUN domain-containing protein. (1361 aa) |
| | GxcP | Uncharacterized protein. (971 aa) |
| | gacJ | Rho GTPase-activating protein gacJ; Rho GTPase-activating protein involved in the signal transduction pathway. (906 aa) |
| | scrA | Protein SCAR; Involved in regulation of actin and microtubule organization. Regulates phagocytosis and macropinocytosis. Belongs to the SCAR/WAVE family. (443 aa) |
| | GxcR | Uncharacterized protein. (550 aa) |
| | grfA | DH domain-containing protein. (1215 aa) |
| | GxcFF | DH domain-containing protein. (741 aa) |
| | DocD | Uncharacterized protein; Belongs to the DOCK family. (1924 aa) |
| | gacC | Rho GTPase-activating protein gacC; Rho GTPase-activating protein involved in the signal transduction pathway. (399 aa) |
| | DDB0218575 | Phospholipase D1-like protein (PLD1). (1129 aa) |
| | gacG | Rho GTPase-activating protein gacG; Rho GTPase-activating protein involved in the signal transduction pathway. (1312 aa) |
| | GxcAA | Uncharacterized protein. (1069 aa) |
| | GxcF | DH domain-containing protein. (932 aa) |
| | gacQ | Rho GTPase-activating protein gacQ; Rho GTPase-activating protein involved in the signal transduction pathway. (531 aa) |
| | GxcV | Uncharacterized protein. (481 aa) |
| | GxcG | DH domain-containing protein. (639 aa) |
| | gacY | Rho GTPase-activating protein gacY; Rho GTPase-activating protein involved in the signal transduction pathway. (721 aa) |
| | gefP | Ras guanine nucleotide exchange factor P; Promotes the exchange of Ras-bound GDP by GTP. (1502 aa) |
| | GxcEE | DH domain-containing protein. (651 aa) |
| | pldA | Phospholipase D A; Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. (1269 aa) |
| | GxcS | Uncharacterized protein. (1137 aa) |
| | GflD | Ras-GEF domain-containing protein. (1765 aa) |
| | pldB | Phospholipase D B; Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. Plays an important role in cell migration by localizing along the anterior cell membrane. Overexpression leads to the inability to aggregate even at higher cell density. Also known as a negative regulator of quorum sensing. (1216 aa) |
| | DDB0205744 | Uncharacterized protein. (1164 aa) |
| | brk1 | Protein BRICK1; Involved in regulation of actin and microtubule organization. Belongs to the BRK1 family. (68 aa) |
| | GxcCC | Uncharacterized protein. (1145 aa) |
| | gacP | Rho GTPase-activating protein gacP; Rho GTPase-activating protein involved in the signal transduction pathway. (576 aa) |
| | gxcII | DH domain-containing protein. (874 aa) |
| | culC-2 | Culmination specific protein 37D. (351 aa) |
| | GxcW | Uncharacterized protein. (1089 aa) |
| | racgef1 | Rac guanyl-nucleotide exchange factor. (1218 aa) |
| | pldC | Phospholipase D C; Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. (1640 aa) |
| | GxcN | Uncharacterized protein. (1094 aa) |
| | gefY | Ras guanine nucleotide exchange factor Y; Promotes the exchange of Ras-bound GDP by GTP. (1508 aa) |
| | gxcJJ | Rac guanine nucleotide exchange factor JJ; GTPase-activating protein. (1173 aa) |
| | ZizC | Uncharacterized protein; Belongs to the DOCK family. (2621 aa) |
| | DocB | Uncharacterized protein; Belongs to the DOCK family. (2176 aa) |
| | pakA | Serine/threonine-protein kinase pakA; Regulator of the myosin II component of the cytoskeleton: required for regulation of cytokinesis. Functions during chemotaxis, required for maintaining the direction of cell movement, suppressing lateral pseudopod extension, and proper retraction of the posterior of chemotaxing cells; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (1197 aa) |
| | pakD | Serine/threonine-protein kinase pakD. (1678 aa) |
| | GxcT | Uncharacterized protein. (1574 aa) |
| | ZizD | Uncharacterized protein; Belongs to the DOCK family. (2162 aa) |
| | gefV | Ras guanine nucleotide exchange factor V; Promotes the exchange of Ras-bound GDP by GTP. (1982 aa) |
| | abiA | Abl interactor homolog; Involved in regulation of actin and microtubule organization. Required for proper cytokinesis; Belongs to the ABI family. (332 aa) |
| | GxcD | Uncharacterized protein. (1063 aa) |
| | gxcGG | Uncharacterized protein. (796 aa) |
| | gefW | Ras guanine nucleotide exchange factor W; Promotes the exchange of Ras-bound GDP by GTP. (1172 aa) |
| | DDB0189391 | Uncharacterized protein. (461 aa) |
| | pakC | Serine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. (477 aa) |
| | sybA | Synaptobrevin-A; Involved in the targeting and/or fusion of transport vesicles to their target membrane. (95 aa) |
| | pirA | Protein pirA; Involved in regulation of actin and microtubule organization. (1336 aa) |
| | ncfA | NADPH oxidase activator; May function as an activator of NOX1, a superoxide-producing NADPH oxidase. (604 aa) |
| | cybA | Superoxide-generating NADPH oxidase light chain subunit; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. (118 aa) |
| | pakB | Serine/threonine-protein kinase pakB; Regulator of the myosin I component of the cytoskeleton: required for regulation of cytokinesis, phagocytosis and pinocytosis. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (852 aa) |
| | napA | Nck-associated protein 1 homolog; Involved in regulation of actin and microtubule organization. Involved in cell adhesion. (1160 aa) |
| | gefQ | Ras guanine nucleotide exchange factor Q; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Seems to play a role in chemotaxis. (1298 aa) |
| | noxB | Superoxide-generating NADPH oxidase heavy chain subunit B; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (698 aa) |
| | GxcX | Uncharacterized protein. (1165 aa) |
| | gacFF | Rho GTPase-activating protein gacFF; Rho GTPase-activating protein involved in the signal transduction pathway. (885 aa) |
| | ZizA | Uncharacterized protein; Belongs to the DOCK family. (2284 aa) |
| | gacH | Rho GTPase-activating protein gacH; Rho GTPase-activating protein involved in the signal transduction pathway. (566 aa) |
| | dst1 | Serine/threonine-protein kinase dst1. (737 aa) |
| | GxcBB | Uncharacterized protein. (1096 aa) |
| | gefE | Ras guanine nucleotide exchange factor E; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Seems to play a role in chemotaxis. (1037 aa) |
| | rdiB | Putative rho GDP-dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. (152 aa) |
| | rdiA | Putative rho GDP-dissociation inhibitor 1; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (By similarity). Regulates the Rac-dependent signaling pathways controlling cytokinesis, actin reorganization and the contractile vacuole. Required for efficient accumulation of cap at the cell cortex. (197 aa) |
| | noxA | Superoxide-generating NADPH oxidase heavy chain subunit A; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (517 aa) |
