STRINGSTRING
rsmD rsmD dymB dymB fszB fszB racF2 racF2 racG racG racH racH racI racI racJ racJ racL racL dymA dymA DDB0167469 DDB0167469 gpaK gpaK rabJ rabJ rab32C rab32C rapB rapB DDB0217939 DDB0217939 rabR rabR rab5A rab5A DDB_G0294583 DDB_G0294583 rabH rabH erf3 erf3 rabW rabW srp54 srp54 DDB0169521 DDB0169521 cpras1 cpras1 Gfm2 Gfm2 gemA gemA rab24 rab24 rab6 rab6 dlpA dlpA rabQ rabQ DDB0202331 DDB0202331 gpaJ gpaJ rabT1 rabT1 rabT2 rabT2 gfm1 gfm1 rab32B rab32B rasW rasW rasV rasV rasX rasX rasY rasY rasU rasU rasZ rasZ gtpbp3 gtpbp3 rapC rapC DDB0191016 DDB0191016 DDB0202803 DDB0202803 dlpC dlpC arrC arrC DDB0216929 DDB0216929 arl5 arl5 rab2B rab2B sarA sarA DDB0217055 DDB0217055 rabF1-1 rabF1-1 rsmE rsmE arrB arrB ranB ranB rabX rabX DDB0202481 DDB0202481 rab1E rab1E DDB0229988 DDB0229988 rheb rheb rab11C rab11C srpra srpra racO racO Gtpbp5 Gtpbp5 fszA fszA racN racN arrL arrL DDB0204436 DDB0204436 rsmK rsmK rsmG rsmG DDB_G0278267 DDB_G0278267 tsr1 tsr1 rsmF rsmF rsmH rsmH DDB0205457 DDB0205457 rsmC rsmC sarB sarB eif5b eif5b eif2s3 eif2s3 rsmJ rsmJ drg2 drg2 Eftud1 Eftud1 DDB_0206311 DDB_0206311 gpaL gpaL DDB_G0280437 DDB_G0280437 arrE arrE arrJ arrJ arrK arrK gbqA gbqA arl2 arl2 rsmB rsmB DDB0204578 DDB0204578 gpn2 gpn2 comB comB rabY rabY arrA arrA rabS rabS DDB0204863 DDB0204863 DDB0204889 DDB0204889 rsmN rsmN DDB0230049 DDB0230049 rabV rabV rab5B rab5B Eftud2 Eftud2 gpaI gpaI arl8 arl8 rsmA rsmA arlD arlD rab32A rab32A HBS1 HBS1 RagC RagC DDB0186059 DDB0186059 rab32D rab32D rab1D rab1D gpn3 gpn3 Gnl1 Gnl1 RacP RacP nog1 nog1 dlpB dlpB DDB0218829 DDB0218829 DDB0187067 DDB0187067 DDB0187261 DDB0187261 gpaC gpaC rab11B rab11B rab7B rab7B cinC cinC Bms1l Bms1l Elp Elp arrH arrH arl1 arl1 ragA ragA arrD arrD racM racM drg1 drg1 arrF arrF tufm tufm rab18 rab18 rabO rabO rabG2 rabG2 rabM rabM rabL rabL rabN1 rabN1 rabK1 rabK1 rabN2 rabN2 rabP rabP rsmL rsmL rabU rabU rabG1 rabG1 rsmM rsmM rab4 rab4 Gtpbp1 Gtpbp1 gpn1 gpn1 cpras2 cpras2 DDB_G0293786 DDB_G0293786 DDB0230045 DDB0230045 racE racE phr phr DDB_G0294569 DDB_G0294569 DDB_G0276007 DDB_G0276007 racQ racQ DDB_G0294577 DDB_G0294577 rabZ rabZ DDB_G0287207 DDB_G0287207 DDB_G0290827 DDB_G0290827 rabK3 rabK3 DDB_G0294571 DDB_G0294571 rabK2 rabK2 DDB_G0292332 DDB_G0292332 rab11A rab11A rab7A rab7A rab14 rab14 rab2A rab2A racD racD racC racC racB racB racA racA rac1C rac1C rac1B rac1B rac1A rac1A rabC rabC rab21 rab21 rabA rabA rab1B rab1B rab1A rab1A gpaH gpaH gpaG gpaG gpaF gpaF gpaE gpaE gpaD gpaD ranA ranA rasS rasS rasC rasC rasB rasB rab8B rab8B rab8A rab8A rapA rapA gpaA gpaA gpaB gpaB efbA efbA rasG rasG eef1a2 eef1a2 eef1a1 eef1a1 rasD rasD racF1 racF1 Rab1C Rab1C spnA spnA arfA arfA guf1 guf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rsmDSmall GTPase. (227 aa)
dymBDynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (920 aa)
fszBMitochondrial division protein fszB; Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family. (366 aa)
racF2Rho-related protein racF2. (193 aa)
racGRho-related protein racG. (201 aa)
racHRho-related protein racH. (200 aa)
racIRho-related protein racI. (205 aa)
racJRho-related protein racJ. (205 aa)
racLRho-related protein racL. (196 aa)
dymADynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway. (853 aa)
DDB0167469Ubiquitin-like domain-containing protein. (684 aa)
gpaKGuanine nucleotide-binding protein-like alpha-11 subunit; Belongs to the G-alpha family. (359 aa)
rabJRas-related protein RabJ. (256 aa)
rab32CRas-related protein Rab-32C; Belongs to the small GTPase superfamily. Rab family. (224 aa)
rapBRas-related protein rapB. (205 aa)
DDB0217939Ubiquitin-like domain-containing protein. (798 aa)
rabRRas-related protein RabR. (307 aa)
rab5ARas-related protein Rab-5A; Required for the fusion of plasma membranes and early endosomes. (201 aa)
DDB_G0294583Ras GTPase. (234 aa)
rabHRas-related protein RabH. (198 aa)
erf3Eukaryotic peptide chain release factor GTP-binding subunit; Involved in translation termination. Stimulates the activity of erf1. Binds guanine nucleotides (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. ERF3 subfamily. (557 aa)
rabWRab GTPase. (218 aa)
srp54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein); Belongs to the GTP-binding SRP family. SRP54 subfamily. (542 aa)
DDB0169521Tr-type G domain-containing protein. (713 aa)
cpras1Circularly permutated Ras protein 1. (842 aa)
Gfm2Tr-type G domain-containing protein. (765 aa)
gemAProbable mitochondrial Rho GTPase gemA; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity). (658 aa)
rab24Ras-related protein Rab-24; May be involved in autophagy-related processes. Belongs to the small GTPase superfamily. Rab family. (202 aa)
rab6Ras-related protein Rab-6; Protein transport. Probably involved in vesicular traffic (By similarity). (208 aa)
dlpADynamin-like protein A; Involved in cytokinesis. May hydrolyze GTP. (880 aa)
rabQRas-related protein RabQ. (204 aa)
DDB0202331G domain-containing protein. (435 aa)
gpaJGuanine nucleotide-binding protein-like alpha-10 subunit; Belongs to the G-alpha family. (349 aa)
rabT1Ras-related protein RabT1. (222 aa)
rabT2Ras-related protein RabT2. (218 aa)
gfm1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (734 aa)
rab32BRas-related protein Rab-32B; Belongs to the small GTPase superfamily. Rab family. (260 aa)
rasWRas-like protein rasW; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa)
rasVRas-like protein rasV; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (229 aa)
rasXRas-like protein rasX; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (213 aa)
rasYRas-like protein rasY; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa)
rasURas-like protein rasU; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (213 aa)
rasZRas-like protein rasZ; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (214 aa)
gtpbp3tRNA modification GTPase gtpbp3, mitochondrial; GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (512 aa)
rapCRas-related protein rapC. (278 aa)
DDB0191016Tr-type G domain-containing protein. (572 aa)
DDB0202803Uncharacterized protein. (415 aa)
dlpCDynamin-like protein C; Involved in cytokinesis. May hydrolyze GTP. (904 aa)
arrCADP-ribosylation factor-related; Belongs to the small GTPase superfamily. Arf family. (200 aa)
DDB0216929Uncharacterized protein. (1603 aa)
arl5ADP-ribosylation factor-like protein 5; May bind and exchange GTP and GDP. (183 aa)
rab2BRas-related protein Rab-2B. (202 aa)
sarAGTP-binding protein Sar1A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (188 aa)
DDB0217055NOG1_N domain-containing protein. (514 aa)
rabF1-1Ras-related protein RabF1. (190 aa)
rsmESmall GTPase. (220 aa)
arrBADP-ribosylation factor-related. (179 aa)
ranBGTP-binding nuclear protein Ran. (754 aa)
rabXRas-related protein RabX. (444 aa)
DDB0202481Tr-type G domain-containing protein. (994 aa)
rab1ERab GTPase. (216 aa)
DDB0229988ADP-ribosylation factor-related. (837 aa)
rhebGTP-binding protein Rheb homolog; Binds GTP and exhibits intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rheb family. (185 aa)
rab11CRas-related protein Rab-11C. (224 aa)
srpraSignal recognition particle receptor subunit alpha; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). (615 aa)
racORho-related protein racO. (276 aa)
Gtpbp5OBG-type G domain-containing protein. (628 aa)
fszAMitochondrial division protein fszA; Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family. (517 aa)
racNRho-related protein racN. (219 aa)
arrLADP-ribosylation factor L; May be involved in trafficking events within the endosomal system. (195 aa)
DDB0204436Uncharacterized protein. (427 aa)
rsmKSmall GTPase. (195 aa)
rsmGSmall GTPase. (202 aa)
DDB_G0278267Uncharacterized protein. (876 aa)
tsr1Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily. (826 aa)
rsmFSmall GTPase. (208 aa)
rsmHSmall GTPase. (272 aa)
DDB0205457Uncharacterized protein. (541 aa)
rsmCSmall GTPase. (240 aa)
sarBGTP-binding protein Sar1B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (194 aa)
eif5bEukaryotic translation initiation factor 5B; Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes; Belongs to the TRAFAC class translation factor [...] (1045 aa)
eif2s3Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] (460 aa)
rsmJSmall GTPase. (192 aa)
drg2Developmentally-regulated GTP-binding protein 2 homolog; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (364 aa)
Eftud1Tr-type G domain-containing protein. (1164 aa)
DDB_0206311Protein SEY1 homolog; Probable GTP-binding protein that may be involved in cell development; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (894 aa)
gpaLGuanine nucleotide-binding protein alpha-12 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. (354 aa)
DDB_G0280437Ras GTPase. (298 aa)
arrEADP-ribosylation factor-related; Belongs to the small GTPase superfamily. Arf family. (197 aa)
arrJADP-ribosylation factor J; GTP-binding protein that may be involved in protein trafficking. May modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); Belongs to the small GTPase superfamily. Arf family. (188 aa)
arrKADP-ribosylation factor K; GTP-binding protein that may be involved in protein trafficking. May modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); Belongs to the small GTPase superfamily. Arf family. (188 aa)
gbqADevelopmental protein DG1120. (581 aa)
arl2ADP-ribosylation factor-like protein 2; May be involved in trafficking events within the endosomal system. (184 aa)
rsmBSmall GTPase. (260 aa)
DDB0204578GB1/RHD3-type G domain-containing protein. (796 aa)
gpn2GPN-loop GTPase 2 homolog; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (315 aa)
comBClu domain-containing protein. (2107 aa)
rabYRas-related protein RabY. (236 aa)
arrAADP-ribosylation factor-related; Belongs to the small GTPase superfamily. Arf family. (197 aa)
rabSRas-related protein RabS. (221 aa)
DDB0204863Uncharacterized protein. (552 aa)
DDB0204889Uncharacterized protein. (257 aa)
rsmNSmall GTPase. (219 aa)
DDB0230049Rab GTPase. (210 aa)
rabVRas-related protein RabV; Belongs to the small GTPase superfamily. Rab family. (233 aa)
rab5BPutative ras-related protein Rab-5B. (214 aa)
Eftud2Tr-type G domain-containing protein. (1018 aa)
gpaIGuanine nucleotide-binding protein alpha-9 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-9 antagonizes broad chemotactic response. It functions rapidly following receptor stimulation to negatively regulate PI3K/PTEN, adenylyl cyclase, and guanylyl cyclase pathways. (342 aa)
arl8ADP-ribosylation factor-like protein 8; Belongs to the small GTPase superfamily. Arf family. (185 aa)
rsmASmall GTPase. (219 aa)
arlDADP-ribosylation factor-like; Belongs to the small GTPase superfamily. Arf family. (216 aa)
rab32ARas-related protein Rab-32A. (219 aa)
HBS1Uncharacterized protein. (729 aa)
RagCUncharacterized protein. (360 aa)
DDB0186059GBP domain-containing protein. (495 aa)
rab32DRas-related protein Rab-32D; Belongs to the small GTPase superfamily. Rab family. (228 aa)
rab1DRas-related protein Rab-1D. (204 aa)
gpn3GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (285 aa)
Gnl1CP-type G domain-containing protein. (846 aa)
RacPRho GTPase. (376 aa)
nog1Probable nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (674 aa)
dlpBDynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP. (808 aa)
DDB0218829Uncharacterized protein. (560 aa)
DDB0187067Uncharacterized protein. (347 aa)
DDB0187261Uncharacterized protein. (1836 aa)
gpaCGuanine nucleotide-binding protein alpha-3 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-3 plays a role in development. G alpha-3 mutants fail to aggregate; Belongs to the G-alpha family. (570 aa)
rab11BRas-related protein Rab-11B. (220 aa)
rab7BRas-related protein Rab-7B; Protein transport. Probably involved in vesicular traffic (By similarity). (197 aa)
cinCElongation factor 2. (853 aa)
Bms1lBms1-type G domain-containing protein. (1205 aa)
ElpEFG_IV domain-containing protein. (839 aa)
arrHADP-ribosylation factor H; GTP-binding protein that may be involved in protein trafficking. May modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); Belongs to the small GTPase superfamily. Arf family. (189 aa)
arl1ARF-like protein; Belongs to the small GTPase superfamily. Arf family. (183 aa)
ragARas-related GTP-binding protein A; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the TOR signaling cascade; Belongs to the GTR/RAG GTP-binding protein family. (301 aa)
arrDADP-ribosylation factor D; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. (216 aa)
racMRho-related protein racM. (189 aa)
drg1Developmentally-regulated GTP-binding protein 1 homolog; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (370 aa)
arrFADP-ribosylation factor F; GTP-binding protein that may be involved in protein trafficking. May modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); Belongs to the small GTPase superfamily. Arf family. (190 aa)
tufmElongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (424 aa)
rab18Ras-related protein Rab-18; Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes (By similarity). (202 aa)
rabORas-related protein RabO. (218 aa)
rabG2Ras-related protein RabG2. (197 aa)
rabMRas-related protein RabM. (202 aa)
rabLRas-related protein RabL. (204 aa)
rabN1Ras-related protein RabN1. (216 aa)
rabK1Ras-related protein RabK1; Belongs to the small GTPase superfamily. Rab family. (213 aa)
rabN2Ras-related protein RabN2; Belongs to the small GTPase superfamily. Rab family. (184 aa)
rabPRas-related protein RabP. (232 aa)
rsmLRab GTPase. (203 aa)
rabURas-related protein RabU; Belongs to the small GTPase superfamily. Rab family. (194 aa)
rabG1Ras-related protein RabG1. (196 aa)
rsmMSmall GTPase. (214 aa)
rab4Ras-related protein Rab-4; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (205 aa)
Gtpbp1Tr-type G domain-containing protein. (677 aa)
gpn1GPN-loop GTPase 1; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (396 aa)
cpras2Circularly permutated Ras protein 2. (3933 aa)
DDB_G0293786Ras GTPase. (277 aa)
DDB0230045Unclassified GTPase. (674 aa)
racERho-related protein racE; Specifically required for cytokinesis; Belongs to the small GTPase superfamily. Rho family. (223 aa)
phrSca1 complex protein phr; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. (1019 aa)
DDB_G0294569Rab GTPase. (179 aa)
DDB_G0276007Rab GTPase. (212 aa)
racQRho GTPase. (185 aa)
DDB_G0294577Rab GTPase. (223 aa)
rabZRas-related protein RabZ. (229 aa)
DDB_G0287207Rab GTPase domain-containing protein. (1685 aa)
DDB_G0290827Rab GTPase domain-containing protein. (250 aa)
rabK3Ras-related protein RabK3; Belongs to the small GTPase superfamily. Rab family. (148 aa)
DDB_G0294571Rab GTPase. (203 aa)
rabK2Ras-related protein RabK2. (147 aa)
DDB_G0292332ADP-ribosylation factor-like protein DDB_G0292332; Binds and exchanges GTP and GDP. (186 aa)
rab11ARas-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. (214 aa)
rab7ARas-related protein Rab-7A; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Involved in lipophagy, a cytosolic lipase-independent autophagic pathway (By similarity); Belongs to the small GTPase superfamily. Rab family. (203 aa)
rab14Ras-related protein Rab-14; Regulates the fusion of phagosomes and lysosomes. Belongs to the small GTPase superfamily. Rab family. (206 aa)
rab2ARas-related protein Rab-2A. (207 aa)
racDRho-related protein racD; Belongs to the small GTPase superfamily. Rho family. (254 aa)
racCRho-related protein racC; Belongs to the small GTPase superfamily. Rho family. (192 aa)
racBRho-related protein racB; Belongs to the small GTPase superfamily. Rho family. (195 aa)
racARho-related protein racA. (598 aa)
rac1CRho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles. (193 aa)
rac1BRho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles. (194 aa)
rac1ARho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family. (194 aa)
rabCRas-related protein RabC. (196 aa)
rab21Ras-related protein Rab-21; Involved in the regulation of phagocytosis. (212 aa)
rabARas-related protein RabA. (201 aa)
rab1BRas-related protein Rab-1B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Rab1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which t [...] (206 aa)
rab1ARas-related protein Rab-1A. (202 aa)
gpaHGuanine nucleotide-binding protein alpha-8 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-8 is a potential analog for the G(s)-like G-proteins which stimulate adenylate cyclase in mammals. (403 aa)
gpaGGuanine nucleotide-binding protein alpha-7 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. (390 aa)
gpaFGuanine nucleotide-binding protein alpha-6 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-6 is involved in the folic acid chemotaxis signal transduction pathway. (347 aa)
gpaEGuanine nucleotide-binding protein alpha-5 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily. (347 aa)
gpaDGuanine nucleotide-binding protein alpha-4 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-4 plays a role in morphogenesis of the multicellular structure. (345 aa)
ranAGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). (212 aa)
rasSRas-like protein rasS; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (194 aa)
rasCRas-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
rasBRas-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (197 aa)
rab8BRas-related protein Rab-8B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (203 aa)
rab8ARas-related protein Rab-8A; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (208 aa)
rapARas-related protein rapA; G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis. May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions. Overexpressing cells generate alterations in cell shape and contractile responses. Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells. (186 aa)
gpaAGuanine nucleotide-binding protein alpha-1 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. (356 aa)
gpaBGuanine nucleotide-binding protein alpha-2 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-2 is required for the early aggregation process and most of the known cAMP receptor-mediated responses. Interacts with downstream effector gflB, a Rap guanine nucleotide exchange factor, to regulate the balance between Ras and Rap signaling at the leading edge of chemotaxing cells. Belongs to the G-alpha family. (357 aa)
efbAElongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (839 aa)
rasGRas-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
eef1a2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. It is also an abundant actin filament bundling protein. (453 aa)
eef1a1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. It is also an abundant actin filament bundling protein. (453 aa)
rasDRas-like protein rasD; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (187 aa)
racF1Rho-related protein racF1; Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes. (193 aa)
Rab1CRas-related protein Rab-1C. (201 aa)
spnAProbable guanine nucleotide-binding protein spalten; Involved in cell-type differentiation and morphogenesis. Dephosphorylates casein; in vitro. May also be involved as modulators or transducers in various transmembrane signaling systems. In the C-terminal section; belongs to the PP2C family. (975 aa)
arfAADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. (182 aa)
guf1Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (685 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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