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DDB_G0269404 DDB_G0269404 mpl2 mpl2 mpl1 mpl1 DDB_G0271350 DDB_G0271350 DDB_G0273199 DDB_G0273199 DDB0217695 DDB0217695 mpl3 mpl3 DDB_G0281963 DDB_G0281963 DDB_G0283417 DDB_G0283417 pteN pteN DDB_G0285967 DDB_G0285967 cnrN cnrN DDB_G0292024 DDB_G0292024 DDB0191697 DDB0191697 DG1060 DG1060 ptpC ptpC ptpB ptpB ptpA1-1 ptpA1-1 cdc25 cdc25 DDB_G0272662 DDB_G0272662 acp1 acp1 DDB0189698 DDB0189698
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDB_G0269404Probable dual specificity protein phosphatase DDB_G0269404; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (212 aa)
mpl2MAP kinase phosphatase with leucine-rich repeats protein 2; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (695 aa)
mpl1MAP kinase phosphatase with leucine-rich repeats protein 1; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins (By similarity). Dephosphorylates pNPP, in vitro. Essential for proper regulation of erkB (erk2) and optimal motility during development; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (834 aa)
DDB_G0271350Probable dual specificity protein phosphatase DDB_G0271350; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (275 aa)
DDB_G0273199Probable rhodanese domain-containing dual specificity protein phosphatase; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (476 aa)
DDB0217695Uncharacterized protein. (527 aa)
mpl3MAP kinase phosphatase with leucine-rich repeats protein 3; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (856 aa)
DDB_G0281963Probable dual specificity protein phosphatase DDB_G0281963; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
DDB_G0283417Probable dual specificity protein phosphatase DDB_G0283417; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (230 aa)
pteN3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] (533 aa)
DDB_G0285967LIM-type zinc finger-containing protein. (998 aa)
cnrNPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells. (639 aa)
DDB_G0292024Probable protein tyrosine phosphatase type IVA A; Belongs to the protein-tyrosine phosphatase family. (166 aa)
DDB0191697Uncharacterized protein. (453 aa)
DG1060Probable tyrosine-protein phosphatase DG1060; Belongs to the protein-tyrosine phosphatase family. (166 aa)
ptpCTyrosine-protein phosphatase 3; Seems to dephosphorylate a protein of 130 kDa (p130). (990 aa)
ptpBTyrosine-protein phosphatase 2. (377 aa)
ptpA1-1Tyrosine-protein phosphatase 1; May have a role in growth and in the early stages of development. Affects the timing of development; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (522 aa)
cdc25M-phase inducer phosphatase; Tyrosine protein phosphatase which may function as a dosage- dependent inducer in mitotic control; Belongs to the MPI phosphatase family. (1053 aa)
DDB_G0272662Probable protein tyrosine phosphatase type IVA B; Belongs to the protein-tyrosine phosphatase family. (163 aa)
acp1Low molecular weight phosphotyrosine protein phosphatase; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (179 aa)
DDB0189698TYR_PHOSPHATASE_2 domain-containing protein. (262 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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