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| | ppox | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (532 aa) |
| | mcfP | Mitochondrial substrate carrier family protein P; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Required for the accumulation of coenzyme A in the mitochondrial matrix (By similarity). (297 aa) |
| | taz | Putative lysophosphatidylcholine acyltransferase; Acyltransferase which mediates the conversion of 1-acyl-sn- glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Required for normal phospholipid content of mitochondrial membranes. Involved in the remodeling of the acyl groups of cardiolipin in the mitochondrial inner membrane, which affects the assembly and stability of respiratory chain complex IV and its supercomplex forms (By similarity). Belongs to the taffazin family. (285 aa) |
| | bcsl1b | Probable mitochondrial chaperone BCS1-B; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III; Belongs to the AAA ATPase family. BCS1 subfamily. (458 aa) |
| | DDB0184120 | Uncharacterized protein. (286 aa) |
| | DDB_G0291852 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages; Belongs to the NDUFAF6 family. (356 aa) |
| | coq6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6; Belongs to the UbiH/COQ6 family. (495 aa) |
| | mcfA | Mitochondrial substrate carrier family protein A; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity). (327 aa) |
| | ndufv2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (247 aa) |
| | ndufa6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (124 aa) |
| | ccs | Probable copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutases. In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. (316 aa) |
| | mcfS | Mitochondrial substrate carrier family protein S; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway (By similarity). (285 aa) |
| | mybO | Myb-like protein O. (1327 aa) |
| | mcfW | Mitochondrial substrate carrier family protein W; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (329 aa) |
| | DDB0188774 | Uncharacterized protein. (654 aa) |
| | phbA | Prohibitin-1, mitochondrial; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. (271 aa) |
| | DDB0188622 | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (977 aa) |
| | DDB0188621 | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (1059 aa) |
| | DDB0188433 | Uncharacterized protein. (831 aa) |
| | cox11 | Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. (312 aa) |
| | DDB0188368 | Peptidase_M48 domain-containing protein. (687 aa) |
| | DDB0188339 | Amino_oxidase domain-containing protein. (464 aa) |
| | DDB0188305 | Uncharacterized protein. (147 aa) |
| | bcs1la | Probable mitochondrial chaperone BCS1-A; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III; Belongs to the AAA ATPase family. BCS1 subfamily. (421 aa) |
| | DDB0219398 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (146 aa) |
| | ndufv1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (479 aa) |
| | hemH | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (423 aa) |
| | abkA | Probable serine/threonine-protein kinase abkA; Belongs to the protein kinase superfamily. ADCK protein kinase family. (565 aa) |
| | hspA | 60 kDa heat shock protein, mitochondrial; Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity). (556 aa) |
| | DDB0187661 | Uncharacterized protein. (461 aa) |
| | timm17 | Mitochondrial import inner membrane translocase subunit tim17; May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family. (183 aa) |
| | yme2 | Mitochondrial escape protein 2 homolog; Plays a role in maintaining the mitochondrial genome. May have a dispensable role in early maturation of pre-rRNA (By similarity); Belongs to the YME2 family. (878 aa) |
| | DDB0187526 | Uncharacterized protein. (455 aa) |
| | fdxr | Probable NADPH:adrenodoxin oxidoreductase, mitochondrial. (515 aa) |
| | DDB0229898 | AAA ATPase domain-containing protein. (574 aa) |
| | DDB0187087 | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (1098 aa) |
| | DDB_G0286541 | Uncharacterized protein. (164 aa) |
| | DDB0186972 | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. (275 aa) |
| | DDB0218794 | Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (921 aa) |
| | Uqcrb | Probable cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] (109 aa) |
| | romo1 | Reactive oxygen species modulator 1 homolog. (128 aa) |
| | ndufa12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (138 aa) |
| | mcfB | Mitochondrial substrate carrier family protein B; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity). (434 aa) |
| | ndufs7 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (178 aa) |
| | sfxn | Sideroflexin; Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria; Belongs to the sideroflexin family. (329 aa) |
| | ndufb9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (106 aa) |
| | ucr | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (214 aa) |
| | timm10 | Mitochondrial import inner membrane translocase subunit Tim10; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity). (88 aa) |
| | abkD | Probable serine/threonine-protein kinase abkD. (695 aa) |
| | OxaA | Uncharacterized protein. (396 aa) |
| | ndufa8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (104 aa) |
| | DDB_G0284693 | Probable cytochrome c oxidase subunit 6B; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane trans [...] (78 aa) |
| | DDB0229917 | AAA ATPase domain-containing protein. (764 aa) |
| | ucpC | Probable mitochondrial 2-oxoglutarate/malate carrier protein; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity). (318 aa) |
| | phbB | Prohibitin-2; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. (293 aa) |
| | grpE | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). (213 aa) |
| | DDB0218541 | Uncharacterized protein. (148 aa) |
| | mcfR | Mitochondrial substrate carrier family protein R; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May be involved in the accumulation of coenzyme A in the mitochondrial matrix (By similarity). (326 aa) |
| | timm22 | Mitochondrial import inner membrane translocase subunit tim22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (179 aa) |
| | atp1 | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (519 aa) |
| | sdhA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (626 aa) |
| | abcB5 | ABC transporter B family member 5. (697 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (192 aa) |
| | ndufs4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (190 aa) |
| | DDB0168999 | LETM1 domain-containing protein. (417 aa) |
| | trap1 | TNF receptor-associated protein 1 homolog, mitochondrial; Chaperone that expresses an ATPase activity. (711 aa) |
| | Ndufs8 | Uncharacterized protein. (210 aa) |
| | ndufa13 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (113 aa) |
| | mcfI | Mitochondrial substrate carrier family protein I; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports folate across the inner membranes of mitochondria (By similarity). (338 aa) |
| | coq9 | Probable ubiquinone biosynthesis protein coq9, mitochondrial; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (307 aa) |
| | mcfF | Mitoferrin; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly (By similarity). (308 aa) |
| | mcfE | Mitochondrial substrate carrier family protein E; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (303 aa) |
| | mcfD | Mitochondrial substrate carrier family protein D; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity). (344 aa) |
| | atp5f1d | ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (170 aa) |
| | DDB_G0268360 | Uncharacterized protein. (94 aa) |
| | mcfT | Probable mitochondrial 2-oxodicarboxylate carrier; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria (By similarity). (300 aa) |
| | DDB0189366 | zf-CHCC domain-containing protein. (99 aa) |
| | DDB_G0268478 | Probable mitochondrial pyruvate carrier 2; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (133 aa) |
| | DDB_G0267508 | Probable mitochondrial pyruvate carrier 1; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (97 aa) |
| | DDB0189322 | AAA domain-containing protein. (720 aa) |
| | atp5f1e | ATP synthase subunit epsilon, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of th [...] (74 aa) |
| | rcaA | AAA domain-containing protein. (844 aa) |
| | mcfX | Mitochondrial substrate carrier family protein X; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (301 aa) |
| | mcfY | Mitochondrial substrate carrier family protein Y; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (436 aa) |
| | dnajc19 | Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). (113 aa) |
| | mcfM | Mitochondrial substrate carrier family protein M; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports folate across the inner membranes of mitochondria (By similarity). (306 aa) |
| | DDB_G0283669 | Probable cytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] (66 aa) |
| | atp5po | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (296 aa) |
| | mcfO | Calcium-binding mitochondrial carrier protein; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. (772 aa) |
| | DDB0215647 | Peptidase_S24 domain-containing protein. (323 aa) |
| | mcfU | Mitochondrial substrate carrier family protein U; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (390 aa) |
| | timm16 | Mitochondrial import inner membrane translocase subunit tim16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. (113 aa) |
| | abkB | Probable serine/threonine-protein kinase abkB; Belongs to the protein kinase superfamily. ADCK protein kinase family. (668 aa) |
| | coq2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB. (463 aa) |
| | oxaB | Uncharacterized protein. (418 aa) |
| | DDB0203965 | Uncharacterized protein. (56 aa) |
| | dgk | Deoxyguanosine kinase; Purine-specific deoxyribonucleoside kinase that phosphorylates preferentially deoxyguanosine, as part of the deoxyribonucleotide salvage pathway; Belongs to the DCK/DGK family. (285 aa) |
| | ndufb7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (112 aa) |
| | Uqcrq | Probable cytochrome b-c1 complex subunit 8; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] (73 aa) |
| | coq7 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides; Belongs to the COQ7 family. (217 aa) |
| | coq5 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (314 aa) |
| | mcfK | Probable mitochondrial thiamine pyrophosphate carrier; Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) |
| | mcfJ | Mitochondrial substrate carrier family protein J; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (345 aa) |
| | mcfL | Mitochondrial substrate carrier family protein L; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (285 aa) |
| | DDB_G0279939 | Uncharacterized protein. (54 aa) |
| | coq3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. (321 aa) |
| | etfdh | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone. Belongs to the ETF-QO/FixC family. (606 aa) |
| | DDB0205475 | Letm1 RBD domain-containing protein. (527 aa) |
| | sdhD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (179 aa) |
| | DDB_G0277049 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (427 aa) |
| | mcfV | Mitochondrial substrate carrier family protein V; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (527 aa) |
| | mcfH | Mitochondrial substrate carrier family protein H; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (366 aa) |
| | cchl | Probable cytochrome c-type heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (211 aa) |
| | DDB0217667 | Uncharacterized protein. (747 aa) |
| | DDB0202593 | Uncharacterized protein. (312 aa) |
| | surf1-1 | SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (270 aa) |
| | coq10-1 | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity). (205 aa) |
| | DDB0168168 | Uncharacterized protein. (260 aa) |
| | DDB0217077 | Uncharacterized protein. (1212 aa) |
| | timm9 | Mitochondrial import inner membrane translocase subunit Tim9; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity). (84 aa) |
| | ndufa9 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (356 aa) |
| | ndufa5 | Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (117 aa) |
| | ucpA | Mitochondrial substrate carrier family protein ucpA; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports oxaloacetate and sulfate (By similarity). (306 aa) |
| | DDB0191062 | NADH-u_ox-rdase domain-containing protein. (114 aa) |
| | DDB0191041 | Uncharacterized protein; Belongs to the MICOS complex subunit Mic60 family. (660 aa) |
| | timm50 | Mitochondrial import inner membrane translocase subunit tim50; Component of the mitochondrial import inner membrane translocase that mediates the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. (374 aa) |
| | DDB_G0270738 | Mitochondrial inner membrane protease ATP23 homolog; Belongs to the peptidase M76 family. (242 aa) |
| | sdhB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (287 aa) |
| | atp5f1b | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (651 aa) |
| | AF310893_3 | Uncharacterized protein. (107 aa) |
| | ucpB | Mitochondrial substrate carrier family protein ucpB; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (294 aa) |
| | mcfC | Mitochondrial substrate carrier family protein C; Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (By similarity). (472 aa) |
| | guf1 | Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (685 aa) |
| | DDB_G0295753 | Mitochondrial substrate carrier family protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa) |
| | cox1/2 | Cytochrome c oxidase subunit 1+2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and [...] (764 aa) |
| | nad2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (488 aa) |
| | cox3 | Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (435 aa) |
| | coxA | Cytochrome c oxidase assembly protein. (482 aa) |
| | ancA | Mitochondrial substrate carrier family protein ancA; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. (309 aa) |
| | cxgE | Cytochrome c oxidase subunit 7e; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (53 aa) |
| | cxgS | Cytochrome c oxidase subunit 7s; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (55 aa) |
| | nad9 | NADH-ubiquinone oxidoreductase subunit 9; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (209 aa) |
| | cxfA | Cytochrome c oxidase polypeptide 6, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembr [...] (93 aa) |
| | cxeA | Cytochrome c oxidase subunit 5; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (120 aa) |
| | cxdA | Cytochrome c oxidase subunit 4, mitochondrial; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (148 aa) |
| | DDB_G0272476 | L51_S25_CI-B8 domain-containing protein. (124 aa) |
| | uqcrh | Probable cytochrome b-c1 complex subunit 6; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] (69 aa) |
| | nad7 | NADH-ubiquinone oxidoreductase 49 kDa subunit; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (406 aa) |
| | atp6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (244 aa) |
| | nad11 | NADH-ubiquinone oxidoreductase 75 kDa subunit; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity). (688 aa) |
| | nad5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (670 aa) |
| | cytB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (389 aa) |
| | nad1 | NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (317 aa) |
| | atp9 | ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (88 aa) |
| | mppB | Mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2 (By similarity). Plays an essential role in mitochondrial biogenesis. (469 aa) |
| | mcfZ | Mitochondrial substrate carrier family protein Z; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. (301 aa) |
| | DDB0219905 | RNA12 domain-containing protein. (760 aa) |
| | mcfN | Mitochondrial substrate carrier family protein N; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Transports phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+) (By similarity). (298 aa) |
| | mcfG | Mitochondrial substrate carrier family protein G; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway (By similarity). (300 aa) |
| | DDB_G0293480 | Uncharacterized protein. (87 aa) |
| | DDB_G0293388 | ATP-dependent metalloprotease. (767 aa) |
| | coq4 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. (286 aa) |
| | DDB0219765 | Uncharacterized protein. (284 aa) |
| | cyc1 | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] (275 aa) |
| | DDB0184385 | Rhomboid domain-containing protein. (440 aa) |
| | atp5f1c | ATP synthase subunit gamma, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (306 aa) |
