13 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pikA	Phosphatidylinositol 3-kinase 1. (1571 aa)
	pikB	Phosphatidylinositol 3-kinase 2. (1857 aa)
	pikC	Phosphatidylinositol 3-kinase 3. (1697 aa)
	pikE	Phosphatidylinositol 3-kinase VPS34-like. (816 aa)
	DDB_G0292252	Putative protein DDB_G0292252. (1256 aa)
	PikH	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1820 aa)
	DDB0188326	Uncharacterized protein. (801 aa)
	atg6B	Beclin-1-like protein B; Involved in autophagy. May be required to recruit the atg8- phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre- autophagosomal structure (By similarity); Belongs to the beclin family. (855 aa)
	vps15	Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1966 aa)
	PikG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1671 aa)
	DDB0218256	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1229 aa)
	atg6A	Beclin-1-like protein A; Involved in autophagy. May be required to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. (1368 aa)
	PikF	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1382 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0188326	DDB0218256	Q54HT3	Q54UU9	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.540
DDB0188326	DDB_G0292252	Q54HT3	Q54DK0	Uncharacterized protein.	Putative protein DDB_G0292252.	0.542
DDB0188326	PikF	Q54HT3	Q55FX5	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.540
DDB0188326	PikG	Q54HT3	Q54S78	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.551
DDB0188326	PikH	Q54HT3	Q54F55	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.544
DDB0188326	atg6A	Q54HT3	Q55CC5	Uncharacterized protein.	Beclin-1-like protein A; Involved in autophagy. May be required to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium.	0.564
DDB0188326	atg6B	Q54HT3	Q54JI9	Uncharacterized protein.	Beclin-1-like protein B; Involved in autophagy. May be required to recruit the atg8- phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre- autophagosomal structure (By similarity); Belongs to the beclin family.	0.561
DDB0188326	pikA	Q54HT3	P54673	Uncharacterized protein.	Phosphatidylinositol 3-kinase 1.	0.540
DDB0188326	pikB	Q54HT3	P54674	Uncharacterized protein.	Phosphatidylinositol 3-kinase 2.	0.540
DDB0188326	pikC	Q54HT3	P54675	Uncharacterized protein.	Phosphatidylinositol 3-kinase 3.	0.540
DDB0188326	pikE	Q54HT3	P54676	Uncharacterized protein.	Phosphatidylinositol 3-kinase VPS34-like.	0.701
DDB0188326	vps15	Q54HT3	Q54S77	Uncharacterized protein.	Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.	0.566
DDB0218256	DDB0188326	Q54UU9	Q54HT3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.540
DDB0218256	DDB_G0292252	Q54UU9	Q54DK0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Putative protein DDB_G0292252.	0.540
DDB0218256	PikF	Q54UU9	Q55FX5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.540
DDB0218256	PikG	Q54UU9	Q54S78	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.540
DDB0218256	PikH	Q54UU9	Q54F55	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.540
DDB0218256	atg6A	Q54UU9	Q55CC5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Beclin-1-like protein A; Involved in autophagy. May be required to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium.	0.540
DDB0218256	atg6B	Q54UU9	Q54JI9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Beclin-1-like protein B; Involved in autophagy. May be required to recruit the atg8- phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre- autophagosomal structure (By similarity); Belongs to the beclin family.	0.540
DDB0218256	pikA	Q54UU9	P54673	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 3-kinase 1.	0.540