8 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	psmD12	26S proteasome non-ATPase regulatory subunit 12; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (447 aa)
	psmD8-1	Probable 26S proteasome non-ATPase regulatory subunit 8; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (263 aa)
	psmD3	26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (504 aa)
	DDB_G0287633	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family. (76 aa)
	psmD13	26S proteasome non-ATPase regulatory subunit 13; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (385 aa)
	psmD11	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family. (413 aa)
	adrm1-1	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation. (287 aa)
	psmD14	26S proteasome non-ATPase regulatory subunit 14; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily. (306 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB_G0287633	adrm1-1	Q54K21	Q556N5	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	0.941
DDB_G0287633	psmD11	Q54K21	Q54UB5	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	0.978
DDB_G0287633	psmD12	Q54K21	Q54UJ0	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	26S proteasome non-ATPase regulatory subunit 12; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.967
DDB_G0287633	psmD13	Q54K21	Q54NQ0	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	26S proteasome non-ATPase regulatory subunit 13; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.976
DDB_G0287633	psmD14	Q54K21	Q86IJ1	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	26S proteasome non-ATPase regulatory subunit 14; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily.	0.938
DDB_G0287633	psmD3	Q54K21	Q1ZXD3	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.996
DDB_G0287633	psmD8-1	Q54K21	P02889	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	Probable 26S proteasome non-ATPase regulatory subunit 8; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.984
adrm1-1	DDB_G0287633	Q556N5	Q54K21	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	0.941
adrm1-1	psmD11	Q556N5	Q54UB5	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	0.995
adrm1-1	psmD12	Q556N5	Q54UJ0	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	26S proteasome non-ATPase regulatory subunit 12; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.991
adrm1-1	psmD13	Q556N5	Q54NQ0	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	26S proteasome non-ATPase regulatory subunit 13; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.994
adrm1-1	psmD14	Q556N5	Q86IJ1	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	26S proteasome non-ATPase regulatory subunit 14; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily.	0.960
adrm1-1	psmD3	Q556N5	Q1ZXD3	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.995
adrm1-1	psmD8-1	Q556N5	P02889	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	Probable 26S proteasome non-ATPase regulatory subunit 8; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.992
psmD11	DDB_G0287633	Q54UB5	Q54K21	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	Probable 26S proteasome complex subunit sem1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family.	0.978
psmD11	adrm1-1	Q54UB5	Q556N5	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.	0.995
psmD11	psmD12	Q54UB5	Q54UJ0	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	26S proteasome non-ATPase regulatory subunit 12; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999
psmD11	psmD13	Q54UB5	Q54NQ0	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	26S proteasome non-ATPase regulatory subunit 13; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999
psmD11	psmD14	Q54UB5	Q86IJ1	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	26S proteasome non-ATPase regulatory subunit 14; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily.	0.997
psmD11	psmD3	Q54UB5	Q1ZXD3	26S proteasome non-ATPase regulatory subunit 11; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, psmD11 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.	26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999