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| | DDB_G0274695 | SH3 and F-BAR domain-containing protein DDB_G0274695. (389 aa) |
| | Dd5P4 | Inositol 5-phosphatase 4. (787 aa) |
| | chmp7 | Charged multivesicular body protein 7; Plays a role in the endosomal sorting pathway; Belongs to the SNF7 family. (477 aa) |
| | lvsB | BEACH domain-containing protein lvsB; Involved in negative regulation of lysosome biogenesis, by limiting the heterotypic fusion of early endosomes and postlysosomal compartments. (4118 aa) |
| | DDB_G0274775 | PH domain-containing protein DDB_G0274775. (458 aa) |
| | chmp4 | Charged multivesicular body protein 4; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins. (215 aa) |
| | vamp7B | Vesicle-associated membrane protein 7B; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion (By similarity); Belongs to the synaptobrevin family. (260 aa) |
| | Syn16B | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (335 aa) |
| | cpnA | Copine-A; Required for cytokinesis, contractile vacuole function and development; Belongs to the copine family. (600 aa) |
| | cnrF | RabGAP/TBC domain-containing protein. (986 aa) |
| | DDB_G0271676 | SH3 and F-BAR domain-containing protein DDB_G0271676. (533 aa) |
| | sybA | Synaptobrevin-A; Involved in the targeting and/or fusion of transport vesicles to their target membrane. (95 aa) |
| | vwkA | Alpha-protein kinase vwkA; Displays a modest preference for threonine over serine residues. Does not phosphorylate myosin II, however can phosphorylate MBP, in vitro. May be involved in the regulation of myosin II function during cytokinesis. Overexpression leads to impaired cell proliferation in suspension culture and fails to develop beyond the mound stage. Both overexpression and absence of the gene can result in defects in cytokinesis and alterations in myosin II abundance and assembly. (625 aa) |
| | DDB0202238 | Uncharacterized protein. (270 aa) |
| | rab32B | Ras-related protein Rab-32B; Belongs to the small GTPase superfamily. Rab family. (260 aa) |
| | Syn1B | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (334 aa) |
| | lvsA | BEACH domain-containing protein lvsA; Involved in myosin-independent cytokinesis and early steps of phagocytosis. Also involved in contractile vacuole-mediated osmoregulation. (3619 aa) |
| | sec31 | Protein transport protein SEC31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1355 aa) |
| | Vps18 | Pep3_Vps18 domain-containing protein. (1077 aa) |
| | DDB_G0269942 | Uncharacterized protein; Belongs to the synaptobrevin family. (214 aa) |
| | mgp2 | Mental retardation GTPase activating protein homolog 2; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. (877 aa) |
| | DDB0190801 | Uncharacterized protein. (646 aa) |
| | DDB0216749 | Uncharacterized protein. (782 aa) |
| | wimA | Protein transport protein sec16; Belongs to the SEC16 family. (1992 aa) |
| | DDB0202904 | Uncharacterized protein. (325 aa) |
| | lvsD | BEACH domain-containing protein lvsD. (2967 aa) |
| | DDB0216913 | Uncharacterized protein. (471 aa) |
| | sarA | GTP-binding protein Sar1A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (188 aa) |
| | DDB0202550 | Uso1_p115_head domain-containing protein. (1048 aa) |
| | DDB0202554 | PH domain-containing protein. (346 aa) |
| | syn8A | Syntaxin-8A; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for fusion of late endosomes with lysosomes and homotypic lysosomal fusion. (152 aa) |
| | DDB0202500 | t-SNARE coiled-coil homology domain-containing protein. (184 aa) |
| | DDB0229988 | ADP-ribosylation factor-related. (837 aa) |
| | DDB0203874 | Uncharacterized protein. (391 aa) |
| | Syn16A | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (314 aa) |
| | syn5 | t-SNARE family protein. (302 aa) |
| | DDB0218004 | CNH domain-containing protein. (1068 aa) |
| | sec24l | Uncharacterized protein. (1133 aa) |
| | vps11 | Vacuolar protein sorting-associated protein 11 homolog; May play a role in vesicle-mediated protein trafficking. Belongs to the VPS11 family. (952 aa) |
| | ClmA | ENTH domain-containing protein. (695 aa) |
| | sarB | GTP-binding protein Sar1B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (194 aa) |
| | syn7B | Probable syntaxin-7B. (286 aa) |
| | ap1b1 | AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis. (942 aa) |
| | DDB0218182 | t-SNARE coiled-coil homology domain-containing protein. (265 aa) |
| | DDB_G0280955 | RabGAP/TBC domain-containing protein. (733 aa) |
| | sec24 | Protein transport protein SEC24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1013 aa) |
| | drkC | Probable serine/threonine-protein kinase drkC. (749 aa) |
| | sec23 | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (750 aa) |
| | DDB0205268 | VWFA domain-containing protein. (698 aa) |
| | DDB0205282 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (568 aa) |
| | sodC | Extracellular superoxide dismutase [Cu-Zn] 3; Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxyde radicals into hydrogen peroxyde and oxygen. (407 aa) |
| | DDB_G0283011 | t-SNARE coiled-coil homology domain-containing protein. (119 aa) |
| | washc4 | WASH complex subunit 4. (1135 aa) |
| | Vti1B | Uncharacterized protein. (269 aa) |
| | yipf5 | Protein YIPF5 homolog; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. (212 aa) |
| | rab32A | Ras-related protein Rab-32A. (219 aa) |
| | gpr89 | Golgi pH regulator homolog. (547 aa) |
| | DDB0185711 | Uncharacterized protein. (351 aa) |
| | DDB0185714 | Uncharacterized protein. (256 aa) |
| | sir2A | NAD-dependent deacetylase sir2A; NAD-dependent deacetylase, which plays an important role in the regulation of transcriptional repression; Belongs to the sirtuin family. (512 aa) |
| | syn6 | t-SNARE coiled-coil homology domain-containing protein. (231 aa) |
| | Syn10 | t-SNARE coiled-coil homology domain-containing protein. (257 aa) |
| | vamp7A | Vesicle-associated membrane protein 7A; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis; Belongs to the synaptobrevin family. (216 aa) |
| | vmp1 | Vacuole membrane protein 1 homolog; Required for organelle biogenesis, protein secretion, and development. Required for maintaining integrity of the endoplasmic reticulum. May play a role in autophagy. (403 aa) |
| | DDB0186473 | t-SNARE coiled-coil homology domain-containing protein. (232 aa) |
| | DDB0186475 | Uncharacterized protein. (63 aa) |
| | Dnajc13 | J domain-containing protein. (2592 aa) |
| | Vps41 | RING-type domain-containing protein; Belongs to the VPS41 family. (1087 aa) |
| | chmp6 | Charged multivesicular body protein 6; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). (218 aa) |
| | rab11B | Ras-related protein Rab-11B. (220 aa) |
| | rab7B | Ras-related protein Rab-7B; Protein transport. Probably involved in vesicular traffic (By similarity). (197 aa) |
| | syn7A | Syntaxin-7A; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for fusion of late endosomes with lysosomes and homotypic lysosomal fusion. May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Belongs to the syntaxin family. (356 aa) |
| | chmp5 | Charged multivesicular body protein 5; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). (215 aa) |
| | DDB0219315 | Uncharacterized protein. (824 aa) |
| | syn8B | Probable syntaxin-8B. (250 aa) |
| | washc5 | WASH complex subunit 5. (1164 aa) |
| | DDB0188240 | Uncharacterized protein. (271 aa) |
| | apm1 | AP-1 complex subunit mu; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis. (428 aa) |
| | Syn1A | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (333 aa) |
| | mgp1 | Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. (920 aa) |
| | sybB | Synaptobrevin-B; Involved in the targeting and/or fusion of transport vesicles to their target membrane; Belongs to the synaptobrevin family. (101 aa) |
| | rabM | Ras-related protein RabM. (202 aa) |
| | rabL | Ras-related protein RabL. (204 aa) |
| | rabN1 | Ras-related protein RabN1. (216 aa) |
| | rabK1 | Ras-related protein RabK1; Belongs to the small GTPase superfamily. Rab family. (213 aa) |
| | rabN2 | Ras-related protein RabN2; Belongs to the small GTPase superfamily. Rab family. (184 aa) |
| | DDB0183788 | PKD_channel domain-containing protein. (823 aa) |
| | vacA2 | RING-type domain-containing protein. (1751 aa) |
| | racGAP | Uncharacterized protein. (1350 aa) |
| | sec13 | Protein SEC13 homolog; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 [...] (301 aa) |
| | DDB0184259 | Arf-GAP domain-containing protein. (522 aa) |
| | DDB0184357 | Uncharacterized protein. (1121 aa) |
| | vti1A | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Belongs to the VTI1 family. (217 aa) |
| | DDB_G0275795 | PH domain-containing protein DDB_G0275795. (808 aa) |
| | DDB_G0290827 | Rab GTPase domain-containing protein. (250 aa) |
| | rabK3 | Ras-related protein RabK3; Belongs to the small GTPase superfamily. Rab family. (148 aa) |
| | DDB_G0294571 | Rab GTPase. (203 aa) |
| | rabK2 | Ras-related protein RabK2. (147 aa) |
| | rtoA | Protein rtoA; May have dual functions, one in vegetative cells at starvation involving cell-type choice and a later function involving progression to the tipped mound stage. Involved in vesicle fusion in endo- and exocytosis. Involved in L.pneumophila intracellular growth. (367 aa) |
| | pikB | Phosphatidylinositol 3-kinase 2. (1857 aa) |
| | pikA | Phosphatidylinositol 3-kinase 1. (1571 aa) |
| | cap | Adenylyl cyclase-associated protein; May have a regulatory bifunctional role. Binds G-actin and PIP2. Involved in microfilament reorganization near the plasma membrane in a PIP2-regulated manner. (464 aa) |
| | rab11A | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. (214 aa) |
| | rab7A | Ras-related protein Rab-7A; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Involved in lipophagy, a cytosolic lipase-independent autophagic pathway (By similarity); Belongs to the small GTPase superfamily. Rab family. (203 aa) |
| | rab14 | Ras-related protein Rab-14; Regulates the fusion of phagosomes and lysosomes. Belongs to the small GTPase superfamily. Rab family. (206 aa) |
| | rab8A | Ras-related protein Rab-8A; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (208 aa) |
| | mhcA | Myosin-2 heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa) |
| | phgA | Drainin; May act as a GTPase-activating protein for Rab family protein(s) (By similarity). Required for osmotic regulation by the contractile vacuole in hypo-osmotic environments. Essential for periodic fusion of the contractile vacuole with the plasma membrane and consequent expulsion of water from the cell body. (438 aa) |
| | DDB_G0274805 | SH3 domain-containing protein. (357 aa) |
| | vps39 | Tetratricopeptide-like helical domain-containing protein. (851 aa) |
| | lmpA | Lysosome membrane protein 2-A; May act as a lysosomal receptor (By similarity). May be involved in macropinocytosis and fluid phase exocytosis. Binds to the anionic phospholipid phosphoinositol 4,5-bisphosphate, but not to phosphatidylcholine and only weakly to phosphatidylserine. Belongs to the CD36 family. (779 aa) |
| | abcG2 | ABC transporter G family member 2; Required for endocytosis and endosomal pH regulation. Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (1328 aa) |
| | racH | Rho-related protein racH. (200 aa) |
| | pcp | Paracaspase; Not required for DIF-induced autophagic cell death and necrotic cell death; Belongs to the peptidase C14B family. (406 aa) |
| | apm3 | AP-3 complex subunit mu; Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway. (421 aa) |
| | dymA | Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway. (853 aa) |
| | abcG18 | ABC transporter G family member 18; Required for endocytosis and endosomal pH regulation. (1476 aa) |
| | rab32C | Ras-related protein Rab-32C; Belongs to the small GTPase superfamily. Rab family. (224 aa) |
