(28 nodes) GDP binding network (Dictyostelium discoideum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rsmJ	Small GTPase. (192 aa)
	rasU	Ras-like protein rasU; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (213 aa)
	rasZ	Ras-like protein rasZ; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (214 aa)
	rapC	Ras-related protein rapC. (278 aa)
	rsmE	Small GTPase. (220 aa)
	rheb	GTP-binding protein Rheb homolog; Binds GTP and exhibits intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rheb family. (185 aa)
	rsmK	Small GTPase. (195 aa)
	rsmG	Small GTPase. (202 aa)
	rsmF	Small GTPase. (208 aa)
	rsmH	Small GTPase. (272 aa)
	DDB_G0280437	Ras GTPase. (298 aa)
	rsmB	Small GTPase. (260 aa)
	rsmA	Small GTPase. (219 aa)
	rasY	Ras-like protein rasY; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa)
	rasX	Ras-like protein rasX; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (213 aa)
	rasV	Ras-like protein rasV; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (229 aa)
	rasW	Ras-like protein rasW; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa)
	cpras1	Circularly permutated Ras protein 1. (842 aa)
	rapB	Ras-related protein rapB. (205 aa)
	rasD	Ras-like protein rasD; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (187 aa)
	rsmD	Small GTPase. (227 aa)
	DDB_G0293786	Ras GTPase. (277 aa)
	phr	Sca1 complex protein phr; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. (1019 aa)
	rasS	Ras-like protein rasS; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (194 aa)
	rasC	Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
	rasB	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (197 aa)
	rapA	Ras-related protein rapA; G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis. May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions. Overexpressing cells generate alterations in cell shape and contractile responses. Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells. (186 aa)
	rasG	Ras-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB_G0280437	rasB	Q54VD5	P32252	Ras GTPase.	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	0.421
DDB_G0280437	rasC	Q54VD5	P32253	Ras GTPase.	Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.419
DDB_G0280437	rasD	Q54VD5	P03967	Ras GTPase.	Ras-like protein rasD; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.421
DDB_G0280437	rasG	Q54VD5	P15064	Ras GTPase.	Ras-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.421
DDB_G0280437	rasS	Q54VD5	P32254	Ras GTPase.	Ras-like protein rasS; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.427
DDB_G0280437	rasU	Q54VD5	Q55CB0	Ras GTPase.	Ras-like protein rasU; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.439
DDB_G0280437	rasV	Q54VD5	Q55CB9	Ras GTPase.	Ras-like protein rasV; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.452
DDB_G0280437	rasW	Q54VD5	Q55CC0	Ras GTPase.	Ras-like protein rasW; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.435
DDB_G0280437	rasX	Q54VD5	Q55CB8	Ras GTPase.	Ras-like protein rasX; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.431
DDB_G0280437	rasY	Q54VD5	Q55CB7	Ras GTPase.	Ras-like protein rasY; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.433
DDB_G0280437	rasZ	Q54VD5	Q55CA9	Ras GTPase.	Ras-like protein rasZ; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.434
DDB_G0280437	rsmB	Q54VD5	Q54U62	Ras GTPase.	Small GTPase.	0.460
DDB_G0293786	rsmA	Q54BC3	Q54QY0	Ras GTPase.	Small GTPase.	0.400
rasB	DDB_G0280437	P32252	Q54VD5	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras GTPase.	0.421
rasB	rasC	P32252	P32253	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.441
rasB	rasD	P32252	P03967	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras-like protein rasD; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.424
rasB	rasG	P32252	P15064	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.423
rasB	rasS	P32252	P32254	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras-like protein rasS; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.438
rasB	rasU	P32252	Q55CB0	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras-like protein rasU; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.439
rasB	rasV	P32252	Q55CB9	Ras-like protein rasB; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.	Ras-like protein rasV; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.433