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| rapA | Ras-related protein rapA; G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis. May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions. Overexpressing cells generate alterations in cell shape and contractile responses. Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells. (186 aa) | ||||
| rasS | Ras-like protein rasS; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (194 aa) | ||||
| arpin | Arpin; Regulates actin polymerization by inhibiting the actin- nucleating activity of the Arp2/3 complex (By similarity). Involved in steering cell migration by controlling its directional persistence. Belongs to the Arpin family. (224 aa) | ||||
| gefB | Ras guanine nucleotide exchange factor B; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Involved in phagocytosis, fluid-phase endocytosis, regulation of macropinocytosis and control of cell movement. (1529 aa) | ||||