(19 nodes) snoRNA binding network (Dictyostelium discoideum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nop10	H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (By similarity). (64 aa)
	Bms1l	Bms1-type G domain-containing protein. (1205 aa)
	Nop14	Uncharacterized protein. (984 aa)
	heatr1	HEAT repeat-containing protein 1 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I; Belongs to the HEATR1/UTP10 family. (2237 aa)
	nop56	Nucleolar protein 56; Required for 60S ribosomal subunit biogenesis; Belongs to the NOP5/NOP56 family. (540 aa)
	Utp15	WD_REPEATS_REGION domain-containing protein. (529 aa)
	wdr3	WD repeat-containing protein 3 homolog. (942 aa)
	utp6	U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family. (609 aa)
	imp4	U3 small nucleolar ribonucleoprotein protein. (286 aa)
	gar1	Probable H/ACA ribonucleoprotein complex subunit 1; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (230 aa)
	Imp3	S4 RNA-binding domain-containing protein. (177 aa)
	tsr1	Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily. (826 aa)
	DDB_G0269284	NKAP family protein; Belongs to the NKAP family. (510 aa)
	nop58	Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis; Belongs to the NOP5/NOP56 family. (638 aa)
	Utp13	WD_REPEATS_REGION domain-containing protein. (902 aa)
	DDB0219852	WD_REPEATS_REGION domain-containing protein. (669 aa)
	nola2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (144 aa)
	DDB0188327	Uncharacterized protein. (840 aa)
	bysl	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. (475 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bms1l	DDB0188327	Q54JS8	Q54HT2	Bms1-type G domain-containing protein.	Uncharacterized protein.	0.509
Bms1l	DDB0219852	Q54JS8	Q54BV0	Bms1-type G domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.996
Bms1l	Imp3	Q54JS8	Q54XG2	Bms1-type G domain-containing protein.	S4 RNA-binding domain-containing protein.	0.995
Bms1l	Nop14	Q54JS8	Q54K79	Bms1-type G domain-containing protein.	Uncharacterized protein.	0.999
Bms1l	Utp13	Q54JS8	Q7KWS8	Bms1-type G domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
Bms1l	Utp15	Q54JS8	Q54QV4	Bms1-type G domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.997
Bms1l	bysl	Q54JS8	Q54IS0	Bms1-type G domain-containing protein.	Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family.	0.998
Bms1l	heatr1	Q54JS8	Q54ML4	Bms1-type G domain-containing protein.	HEAT repeat-containing protein 1 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I; Belongs to the HEATR1/UTP10 family.	0.999
Bms1l	imp4	Q54JS8	C7G018	Bms1-type G domain-containing protein.	U3 small nucleolar ribonucleoprotein protein.	0.997
Bms1l	nola2	Q54JS8	Q54H53	Bms1-type G domain-containing protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.811
Bms1l	nop10	Q54JS8	Q54J26	Bms1-type G domain-containing protein.	H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (By similarity).	0.421
Bms1l	nop56	Q54JS8	Q54MT2	Bms1-type G domain-containing protein.	Nucleolar protein 56; Required for 60S ribosomal subunit biogenesis; Belongs to the NOP5/NOP56 family.	0.998
Bms1l	nop58	Q54JS8	Q55FI4	Bms1-type G domain-containing protein.	Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis; Belongs to the NOP5/NOP56 family.	0.997
Bms1l	tsr1	Q54JS8	Q54YA7	Bms1-type G domain-containing protein.	Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.	0.906
Bms1l	utp6	Q54JS8	Q54WN5	Bms1-type G domain-containing protein.	U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family.	0.998
Bms1l	wdr3	Q54JS8	Q54S79	Bms1-type G domain-containing protein.	WD repeat-containing protein 3 homolog.	0.999
DDB0188327	Bms1l	Q54HT2	Q54JS8	Uncharacterized protein.	Bms1-type G domain-containing protein.	0.509
DDB0188327	DDB0219852	Q54HT2	Q54BV0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.918
DDB0188327	Imp3	Q54HT2	Q54XG2	Uncharacterized protein.	S4 RNA-binding domain-containing protein.	0.872
DDB0188327	Nop14	Q54HT2	Q54K79	Uncharacterized protein.	Uncharacterized protein.	0.970