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| | cdc26 | Anaphase-promoting complex subunit cdc26; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the CDC26 family. (69 aa) |
| | culD | Cullin-4; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). (802 aa) |
| | anapc7 | Anaphase-promoting complex subunit 7; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC7 family. (580 aa) |
| | DDB0184379 | BTB domain-containing protein. (400 aa) |
| | DDB0184244 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1569 aa) |
| | DDB0184243 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (388 aa) |
| | Wdr23 | WD_REPEATS_REGION domain-containing protein. (661 aa) |
| | DDB0184076 | Uncharacterized protein. (956 aa) |
| | DDB0191588 | Uncharacterized protein. (502 aa) |
| | DDB0183778 | Uncharacterized protein. (543 aa) |
| | DDB0189261 | Uncharacterized protein. (938 aa) |
| | DDB0189211 | Uncharacterized protein. (382 aa) |
| | DDB0189206 | Uncharacterized protein. (865 aa) |
| | DDB0189195 | F-box domain-containing protein. (789 aa) |
| | ascc3 | Activating signal cointegrator 1 complex subunit 3. (2195 aa) |
| | nploc4 | Nuclear protein localization protein 4 homolog; May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. Belongs to the NPL4 family. (576 aa) |
| | atg5 | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3- like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity). (398 aa) |
| | DDB0188474 | Uncharacterized protein. (1268 aa) |
| | derl1 | Probable derlin-1 homolog; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. May also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation. Belongs to the derlin family. (242 aa) |
| | DDB0219346 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2023 aa) |
| | DDB0219336 | Uncharacterized protein. (970 aa) |
| | anapc3 | Anaphase-promoting complex subunit 3; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC3/CDC27 family. (970 aa) |
| | DDB0187780 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa) |
| | DDB0187732 | Vac14_Fab1_bd domain-containing protein. (1878 aa) |
| | psmD1 | 26S proteasome non-ATPase regulatory subunit 1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (975 aa) |
| | DDB0187644 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1814 aa) |
| | DDB0215923 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1580 aa) |
| | DDB0187476 | Uncharacterized protein. (1012 aa) |
| | cdh1 | Anaphase-promoting complex subunit cdh1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (754 aa) |
| | DDB0187369 | HECT domain-containing protein. (1898 aa) |
| | anapc11 | Anaphase-promoting complex subunit 11; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the RING-box family. (87 aa) |
| | ube2j2 | Ubiquitin-conjugating enzyme E2 J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum; Belongs to the ubiquitin-conjugating enzyme family. (241 aa) |
| | rcbA | UV excision repair protein RAD23 homolog; May play a role both in proteasomal degradation of misfolded proteins and DNA repair; Belongs to the RAD23 family. (342 aa) |
| | DDB0186757 | Uncharacterized protein. (906 aa) |
| | DDB0186668 | RING-CH-type domain-containing protein. (1088 aa) |
| | cdc20 | Anaphase-promoting complex subunit cdc20; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the WD repeat CDC20/Fizzy family. (499 aa) |
| | atg9 | Autophagy-related protein 9; Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway; Belongs to the ATG9 family. (699 aa) |
| | anapc1 | Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC1 family. (2269 aa) |
| | anapc4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC4 family. (837 aa) |
| | DDB0186377 | Uncharacterized protein. (473 aa) |
| | derl2 | Probable derlin-2 homolog; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation. Belongs to the derlin family. (254 aa) |
| | DDB0186240 | Skp1 domain-containing protein. (404 aa) |
| | DDB0218617 | Uncharacterized protein. (982 aa) |
| | psmC6 | 26S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (393 aa) |
| | maea | Uncharacterized protein. (423 aa) |
| | psmC3 | 26S proteasome regulatory subunit 6A homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (421 aa) |
| | DDB0218572 | Uncharacterized protein. (232 aa) |
| | DDB0218563 | PlsC domain-containing protein. (310 aa) |
| | DDB0185786 | Ubiquitin-like domain-containing protein. (836 aa) |
| | DDB0218548 | HECT domain-containing protein. (1120 aa) |
| | DDB0185644 | Uncharacterized protein. (1071 aa) |
| | DDB0185543 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2375 aa) |
| | migA | Uncharacterized protein. (863 aa) |
| | DDB0185326 | WD_REPEATS_REGION domain-containing protein. (891 aa) |
| | DDB0204986 | J domain-containing protein. (407 aa) |
| | PsmF1 | Uncharacterized protein. (326 aa) |
| | DDB_G0282185 | RING zinc finger-containing protein. (790 aa) |
| | DDB0204663 | J domain-containing protein. (445 aa) |
| | DDB0218298 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (401 aa) |
| | DDB_G0280895 | WD40 repeat-containing protein. (1501 aa) |
| | ascc2 | Activating signal cointegrator 1 complex subunit 2 homolog; Enhances NF-kappa-B, SRF and AP1 transactivation. Belongs to the ASCC2 family. (941 aa) |
| | DDB0205191 | UBX domain-containing protein. (362 aa) |
| | sgt | Small glutamine-rich tetratricopeptide repeat-containing protein; May act as a co-chaperone and regulate the ATPase activity of heat shock proteins. (334 aa) |
| | anapc5 | Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC5 family. (1017 aa) |
| | psmD7 | 26S proteasome non-ATPase regulatory subunit 7; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (325 aa) |
| | DDB0205758 | BTB domain-containing protein. (1238 aa) |
| | DDB_G0279421 | Ubiquitin-like domain-containing protein. (271 aa) |
| | DDB_G0279265 | Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation; Belongs to the GID8 family. (228 aa) |
| | culE | Cullin-5; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). (750 aa) |
| | DDB0215276 | RING-type domain-containing protein. (355 aa) |
| | ube2c | Probable ubiquitin-conjugating enzyme E2 C; Catalyzes the covalent attachment of ubiquitin to other proteins. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. (153 aa) |
| | DDB0205456 | Uncharacterized protein. (353 aa) |
| | DDB_G0278327 | TPR_REGION domain-containing protein. (558 aa) |
| | DDB_G0278075 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (232 aa) |
| | DDB0218023 | Uncharacterized protein. (586 aa) |
| | DDB0217882 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (632 aa) |
| | Ercc8 | Uncharacterized protein. (513 aa) |
| | anapc2 | Anaphase-promoting complex subunit 2; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the cullin family. (907 aa) |
| | psmD4 | 26S proteasome non-ATPase regulatory subunit 4; Binds and presumably selects ubiquitin-conjugates for destruction; Belongs to the proteasome subunit S5A family. (349 aa) |
| | ubc2 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. (151 aa) |
| | DDB0217570 | DUSP domain-containing protein. (404 aa) |
| | rnf160 | E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to cdcD/CDC48 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family. (1864 aa) |
| | DDB0217500 | CTLH domain-containing protein. (414 aa) |
| | DDB0190543 | UBX domain-containing protein. (264 aa) |
| | psmD6 | 26S proteasome non-ATPase regulatory subunit 6; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (382 aa) |
| | DDB0190877 | Uncharacterized protein. (1154 aa) |
| | psmC1 | 26S proteasome regulatory subunit 4 homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). Plays an important role in regulating both growth and multicellular development. (439 aa) |
| | ubxd7 | UBX domain-containing protein 7 homolog. (503 aa) |
| | ufd1 | Ubiquitin fusion degradation protein 1 homolog; Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway; Belongs to the UFD1 family. (330 aa) |
| | yod1 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. (325 aa) |
| | Usp14 | Ubiquitin carboxyl-terminal hydrolase. (512 aa) |
| | cnxA | Uncharacterized protein. (536 aa) |
| | DDB_G0272975 | BTB domain-containing protein. (692 aa) |
| | DDB0217070 | Uncharacterized protein. (572 aa) |
| | fpaB-1 | SCF ubiquitin ligase complex protein SKP1b(4-162). (162 aa) |
| | psmB3 | Proteasome subunit beta type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family. (205 aa) |
| | armc8 | Armadillo repeat-containing protein. (702 aa) |
| | DDB0201756 | ANK_REP_REGION domain-containing protein. (787 aa) |
| | bzpE | Probable basic-leucine zipper transcription factor E; Probable transcriptional regulator; Belongs to the bZIP family. (418 aa) |
| | DDB0202360 | BTB domain-containing protein. (346 aa) |
| | anapc10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC10 family. (188 aa) |
| | DDB0190003 | UBX domain-containing protein. (409 aa) |
| | ube2w | Probable ubiquitin-conjugating enzyme E2 W; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family. (149 aa) |
| | psmA5 | Proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family. (241 aa) |
| | DDB0216561 | F-box domain-containing protein. (676 aa) |
| | DDB0189563 | Uncharacterized protein. (665 aa) |
| | psmB6 | Proteasome subunit beta type-6; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (214 aa) |
| | DDB0168503 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (171 aa) |
| | DDB0169450 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2230 aa) |
| | DDB_G0288313 | Uncharacterized protein. (1040 aa) |
| | repE | DNA damage-binding protein 1; Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair (By similarity). (1181 aa) |
| | DDB_G0285063 | Uncharacterized protein. (3792 aa) |
| | tipD | Protein tipD; Not known; disruption of the gene for tipD results in morphological defects. (612 aa) |
| | nosA | NOSA. (1089 aa) |
| | culA | Cullin-1; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). Required at several stages during development. CulA and fbxA regulate multicellular development by targeting regA for degradation via a pathway that requires erkB function, leading to an increase in cAMP and PKA activity. (770 aa) |
| | psmD8-1 | Probable 26S proteasome non-ATPase regulatory subunit 8; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (263 aa) |
| | DDB_G0295729 | J domain-containing protein DDB_G0295729. (1346 aa) |
| | DDB_G0349043 | WD repeat-containing protein DDB_G0349043. (588 aa) |
| | psmC4 | 26S proteasome regulatory subunit 6B homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (403 aa) |
| | psmC5 | 26S proteasome regulatory subunit 8; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (403 aa) |
| | fpaA | SCF ubiquitin ligase complex protein SKP1a(4-162); Belongs to the SKP1 family. (162 aa) |
| | cdcD | Cell division cycle protein 48; Belongs to the AAA ATPase family. (793 aa) |
| | anapc6 | Anaphase-promoting complex subunit 6; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC6/CDC16 family. (865 aa) |
| | crtA | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). (424 aa) |
| | DDB_G0294380 | Ubiquitin-conjugating enzyme E2 J2-like; Catalyzes the covalent attachment of ubiquitin to other proteins. (170 aa) |
| | psmD2 | 26S proteasome non-ATPase regulatory subunit 2; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (893 aa) |
| | psmB5 | Proteasome subunit beta type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family. (272 aa) |
| | nsfl1c | NSFL1 cofactor p47 homolog; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER) (By similarity). (415 aa) |
| | DDB0168784 | Uncharacterized protein. (538 aa) |
| | DDB0168794 | Uncharacterized protein. (630 aa) |
| | DDB0167344 | Ubiquitin-like domain-containing protein. (184 aa) |
| | DDB0167912 | UBX domain-containing protein. (662 aa) |
| | anapc8 | Anaphase-promoting complex subunit 8; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle; Belongs to the APC8/CDC23 family. (592 aa) |
| | atg12 | Ubiquitin-like protein atg12; Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity); Belongs to the ATG12 family. (124 aa) |
| | DDB0217687 | PRKCSH domain-containing protein. (318 aa) |
| | psmD14 | 26S proteasome non-ATPase regulatory subunit 14; Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily. (306 aa) |
| | psmC2 | 26S proteasome regulatory subunit 7; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (428 aa) |
| | bip2 | Luminal-binding protein 2; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER; Belongs to the heat shock protein 70 family. (658 aa) |
| | grp94 | Endoplasmin homolog; May play a role in late differentiation as well as in starvation response. When overexpressed, suppresses the ability to form normal fruiting bodies and impairs prespore differentiation as well as maturation into spores; Belongs to the heat shock protein 90 family. (768 aa) |
| | culB | Cullin-2; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). Appears to ensure that the proper number of prestalk cells differentiate at the appropriate time in development. May govern prestalk cell differentiation. (771 aa) |
