25 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Dd5P4	Inositol 5-phosphatase 4. (787 aa)
	pteN	3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] (533 aa)
	DDB0185955	Uncharacterized protein. (1272 aa)
	DDB_G0288731	GRAM domain-containing protein. (1227 aa)
	DDB0191855	Myotubularin phosphatase domain-containing protein. (1192 aa)
	DDB0191697	Uncharacterized protein. (453 aa)
	Dd5P3	Inositol 5-phosphatase. (1379 aa)
	DDB0219574	Uncharacterized protein. (1717 aa)
	DDB_G0290005	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. (1324 aa)
	cnrN	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells. (639 aa)
	DDB_G0285967	LIM-type zinc finger-containing protein. (998 aa)
	DDB0186027	Myotubularin phosphatase domain-containing protein. (1028 aa)
	DDB0167752	Uncharacterized protein. (1438 aa)
	DDB0190143	Uncharacterized protein. (1214 aa)
	pats1	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton. (3184 aa)
	DDB0190271	Uncharacterized protein. (1292 aa)
	DDB0191072	Uncharacterized protein. (448 aa)
	DDB0216866	Myotubularin phosphatase domain-containing protein. (1738 aa)
	sac1	Phosphatidylinositide phosphatase SAC1; Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. (581 aa)
	DDB0217695	Uncharacterized protein. (527 aa)
	DDB0205364	Myotubularin phosphatase domain-containing protein. (1002 aa)
	Dd5P1	Inositol 5-phosphatase. (940 aa)
	DDB0205575	SAC domain-containing protein. (1391 aa)
	DDB0204242	Myotubularin phosphatase domain-containing protein. (1343 aa)
	Dd5P2	Inositol 5-phosphatase. (1800 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0186027	DDB0190143	Q54PL3	Q55EE1	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.472
DDB0186027	DDB0190271	Q54PL3	Q55E04	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.470
DDB0186027	DDB0191855	Q54PL3	Q54C52	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.523
DDB0186027	DDB0204242	Q54PL3	Q54TD5	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB0205364	Q54PL3	Q54YC2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.502
DDB0186027	DDB0216866	Q54PL3	Q55AZ2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB_G0288731	Q54PL3	Q1ZXD2	Myotubularin phosphatase domain-containing protein.	GRAM domain-containing protein.	0.497
DDB0186027	DDB_G0290005	Q54PL3	Q54GQ1	Myotubularin phosphatase domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.518
DDB0186027	Dd5P3	Q54PL3	Q54D97	Myotubularin phosphatase domain-containing protein.	Inositol 5-phosphatase.	0.434
DDB0186027	pats1	Q54PL3	Q55E58	Myotubularin phosphatase domain-containing protein.	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton.	0.400
DDB0190143	DDB0186027	Q55EE1	Q54PL3	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.472
DDB0190143	DDB0190271	Q55EE1	Q55E04	Uncharacterized protein.	Uncharacterized protein.	0.426
DDB0190143	DDB0191855	Q55EE1	Q54C52	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.471
DDB0190143	DDB0204242	Q55EE1	Q54TD5	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.487
DDB0190143	DDB0205364	Q55EE1	Q54YC2	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.461
DDB0190143	DDB0216866	Q55EE1	Q55AZ2	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.472
DDB0190143	DDB_G0288731	Q55EE1	Q1ZXD2	Uncharacterized protein.	GRAM domain-containing protein.	0.473
DDB0190143	DDB_G0290005	Q55EE1	Q54GQ1	Uncharacterized protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.484
DDB0190143	Dd5P3	Q55EE1	Q54D97	Uncharacterized protein.	Inositol 5-phosphatase.	0.440
DDB0190143	pats1	Q55EE1	Q55E58	Uncharacterized protein.	Probable serine/threonine-protein kinase pats1; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor (By similarity). Essential regulator of cytokinesis involved in the binding to actomyosin cytoskeleton.	0.400