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| | alyD-1 | Lysozyme D; Has antibacterial activity; Belongs to the dictyostelium lysozyme family. (260 aa) |
| | DDB_G0272484 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog; Has deoxynucleoside triphosphate (dNTPase) activity. (514 aa) |
| | DDB_G0295679 | Helicase superfamily 1 and 2 domain-containing protein. (1123 aa) |
| | pip5k3 | 1-phosphatidylinositol 3-phosphate 5-kinase; Catalyzes the phosphorylation of phosphatidylinositol 3- phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. (2656 aa) |
| | DDB_G0294629 | SET domain-containing protein. (594 aa) |
| | DDB_G0295789 | Mrr_cat domain-containing protein. (159 aa) |
| | vacA | Vacuolin-A; Belongs to the vacuolin family. (598 aa) |
| | Rab1C | Ras-related protein Rab-1C. (201 aa) |
| | dscA-1 | Discoidin-1 subunit A; Galactose- and N-acetylgalactosamine-binding lectin. May play a role in cell-substratum adhesion rather than in cell-cell adhesion. May be necessary for the maintenance of normal elongate morphology during aggregation. (253 aa) |
| | rasD | Ras-like protein rasD; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (187 aa) |
| | eef1a1 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. It is also an abundant actin filament bundling protein. (453 aa) |
| | cofA | Cofilin-1A; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity); Belongs to the actin-binding proteins ADF family. (137 aa) |
| | cofB | Cofilin-1B; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity); Belongs to the actin-binding proteins ADF family. (137 aa) |
| | acpA | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa) |
| | acpB | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (281 aa) |
| | efbA | Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (839 aa) |
| | rab8B | Ras-related protein Rab-8B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (203 aa) |
| | myoA | Myosin IA heavy chain; Actin-based motor protein, possibly involved in a wide range of motile processes, such as cell movement across a surface, and extension and retraction of pseudopodia or lamellipodia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (994 aa) |
| | ndkC-1 | Nucleoside diphosphate kinase, cytosolic; Major role in the synthesis of nucleoside triphosphates other than ATP; Belongs to the NDK family. (155 aa) |
| | nxnA | Annexin A7; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. (462 aa) |
| | corA | Coronin-A; Required for normal motility. Participates in cytokinesis. (445 aa) |
| | cxeA | Cytochrome c oxidase subunit 5; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (120 aa) |
| | tubB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (455 aa) |
| | myoB | Myosin IB heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Myosin IB may have a role in chemotaxis and aggregation; it could serve to stabilize and even retract cortical structures, such as pseudopods and lamellopods. Involved in the whole cell motility of aggregation-stages cells. Overexpression results in significant decrease in the rate of cellular translocation and fluid-phase pinocytosis and abnormalities in the normal rearrangement of the actin cytoskeleton. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myos [...] (1111 aa) |
| | ndkM | Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (220 aa) |
| | mvpA | Major vault protein alpha; Unknown, though MVP-alpha is required for normal vault structure. (843 aa) |
| | coaA | Coactosin; Binds to F-actin in a calcium independent manner. Binds to the filaments along their length. (146 aa) |
| | rac1B | Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles. (194 aa) |
| | rac1C | Rho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles. (193 aa) |
| | racA | Rho-related protein racA. (598 aa) |
| | rab14 | Ras-related protein Rab-14; Regulates the fusion of phagosomes and lysosomes. Belongs to the small GTPase superfamily. Rab family. (206 aa) |
| | erkA | Extracellular signal-regulated kinase 1; Kinase involved in a signal transduction pathway. (529 aa) |
| | arpC | Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. The Arp2/3 complex is involved in organizing the actin system in cell motility and chemotaxis, in phagocytosis and macropinocytosis, at late steps of endosome processing, and in mitosis. In concert with a group of other proteins, the Arp2/3 complex plays a general role in [...] (418 aa) |
| | dscE | Discoidin-2; Galactose-binding lectin. May be necessary for the primary process of spore formation and may be involved in spore coat formation. (257 aa) |
| | fttB | 14-3-3-like protein; Belongs to the 14-3-3 family. (252 aa) |
| | vatA | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (618 aa) |
| | cadA | Calcium-dependent cell adhesion molecule 1; Mediates calcium-dependent cell-cell adhesion during the early stage of development. (213 aa) |
| | pikA | Phosphatidylinositol 3-kinase 1. (1571 aa) |
| | pikB | Phosphatidylinositol 3-kinase 2. (1857 aa) |
| | pikC | Phosphatidylinositol 3-kinase 3. (1697 aa) |
| | cdcD | Cell division cycle protein 48; Belongs to the AAA ATPase family. (793 aa) |
| | comA | Comitin; May have a role in cell motility. It has high affinity for both G-actin and F-actin. Binds to vesicle membranes via mannose residues and, by way of its interaction with actin, links these membranes to the cytoskeleton. (185 aa) |
| | ptsA | 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity); Belongs to the PTPS family. (135 aa) |
| | crtA | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). (424 aa) |
| | pkiA | Protein pkiA. (127 aa) |
| | DDB_G0293566 | Probable GH family 25 lysozyme 5; Belongs to the glycosyl hydrolase 25 family. (216 aa) |
| | DDB_G0293492 | Probable GH family 25 lysozyme 4; Belongs to the glycosyl hydrolase 25 family. (213 aa) |
| | sapA1 | Saposin A. (143 aa) |
| | abcG10 | ABC transporter G family member 10. (1466 aa) |
| | DDB_G0292878 | WAS protein family homolog DDB_G0292878; Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization. (472 aa) |
| | DDB0184284 | Uncharacterized protein. (1825 aa) |
| | pdi2 | Protein disulfide-isomerase 2; Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer. (513 aa) |
| | noxC | Superoxide-generating NADPH oxidase heavy chain subunit C; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (1142 aa) |
| | PikH | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1820 aa) |
| | mppA2 | Mitochondrial-processing peptidase subunit alpha-2; Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. (445 aa) |
| | DDB_G0290491 | Autophagy-related protein 8-like protein DDB_G0290491. (126 aa) |
| | agnB | Argonaut-like protein. (900 aa) |
| | sprA | Sepiapterin reductase; Catalyzes the production of D-threo-tetrahydrobiopterin (DH4), also known as dictyopterin, and in a much smaller amount that of it's stereoisomer L-erythro-tetrahydrobiopterin (BH4). Prefers 1-oxo-2- D-hydroxypropyl-tetrahydropterin to 6-pyruvoyltetrahydropterin as a substrate, thereby maintaining dominant production of DH4 over BH4 in sufficient supply of an aldose reductase-like enzyme. DH4 represents more than 95% of the total tetrahydrobiopterin production. It has a direct antioxidant function to protect mitochondria against oxidative stress. (267 aa) |
| | atg5 | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3- like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity). (398 aa) |
| | ctxA | Cortexillin-1; Actin-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1; Belongs to the cortexillin family. (444 aa) |
| | rmp | RNA polymerase II subunit 5-mediating protein homolog. (489 aa) |
| | tirA | Protein tirA; May regulate responses to pathogens. Required by to respond appropriately to bacteria during vegetative foraging. (1336 aa) |
| | litaf | Cell death-inducing p53-target protein 1 homolog; Belongs to the CDIP1/LITAF family. (181 aa) |
| | smt1 | Probable cycloartenol-C-24-methyltransferase 1; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of cycloartenol to form 24-methylene cycloartenol. (354 aa) |
| | hspA | 60 kDa heat shock protein, mitochondrial; Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity). (556 aa) |
| | vps13F | Putative vacuolar protein sorting-associated protein 13F; Required for sorting signal-dependent recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (4246 aa) |
| | alyL | Putative lysozyme-like protein; Belongs to the dictyostelium lysozyme family. (572 aa) |
| | DDB0186786 | RNA_lig_T4_1 domain-containing protein. (443 aa) |
| | atg9 | Autophagy-related protein 9; Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway; Belongs to the ATG9 family. (699 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase A. (317 aa) |
| | DDB0185999 | Fe2OG dioxygenase domain-containing protein. (252 aa) |
| | vps4 | Vacuolar protein sorting-associated protein 4; Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment. May be involved in the release of components of the bilayered coat from the endosomal membrane. The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex (By similarity); Belongs to the AAA ATPase family. (444 aa) |
| | rps12 | 40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (136 aa) |
| | sapA | Saposin A. (522 aa) |
| | Atp7a | Uncharacterized protein. (985 aa) |
| | erkB | Extracellular signal-regulated kinase 2; Implicated in the relay of the cAMP chemotactic signal and cell differentiation. Important for receptor-mediated activation of adenylyl cyclase. (369 aa) |
| | DDB_G0283629 | Probable zinc transporter protein DDB_G0283629; May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (543 aa) |
| | PikG | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1671 aa) |
| | DDB_G0282067 | Probable zinc transporter protein DDB_G0282067; May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces. (573 aa) |
| | DDB0204246 | Uncharacterized protein. (1630 aa) |
| | drkD | Probable serine/threonine-protein kinase drkD; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. (1288 aa) |
| | far1 | Metabotropic glutamate receptor-like protein L; In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily. (708 aa) |
| | udpB | Uridine phosphorylase. (289 aa) |
| | fumH | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. (485 aa) |
| | DDB0218187 | Uncharacterized protein. (381 aa) |
| | DDB0205997 | Uncharacterized protein. (217 aa) |
| | DDB0205958 | Uncharacterized protein. (1333 aa) |
| | glnA3 | Type-3 glutamine synthetase; Belongs to the glutamine synthetase family. Type 3 subfamily. (735 aa) |
| | vacB | Vacuolin-B; Negative regulator of late steps of the endocytic pathway. (592 aa) |
| | vacC | Vacuolin-C; Belongs to the vacuolin family. (586 aa) |
| | rpl21 | 60S ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family. (160 aa) |
| | DDB0218156 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1158 aa) |
| | DDB_G0278481 | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family. (508 aa) |
| | DDB0218082 | Uncharacterized protein. (333 aa) |
| | racO | Rho-related protein racO. (276 aa) |
| | nramp2 | Natural resistance-associated macrophage protein 2 homolog; Divalent transition metal (iron and manganese) transporter. Belongs to the NRAMP family. (629 aa) |
| | cnrD | Putative countin receptor Cnr4. (362 aa) |
| | eif3d | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (527 aa) |
| | DDB_G0274831 | Probable T4-type lysozyme 1. (170 aa) |
| | cf50-1 | Counting factor 50; Cell-counting factor that limits the maximum size of the multicellular structure during aggregation. Has a very low lysozyme activity. (303 aa) |
| | atg12 | Ubiquitin-like protein atg12; Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity); Belongs to the ATG12 family. (124 aa) |
| | atg8 | Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. Participates in membrane fusion events that take place in the secretory pathway (By similarity); Belongs to the ATG8 family. (122 aa) |
| | atg7 | Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. (707 aa) |
| | atg1 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. (668 aa) |
| | noxB | Superoxide-generating NADPH oxidase heavy chain subunit B; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (698 aa) |
| | cf45-1 | Counting factor 45-1; Cell-counting factor that limits the maximum size of the multicellular structure during aggregation. (297 aa) |
| | omt6 | Probable caffeoyl-CoA O-methyltransferase 2. (231 aa) |
| | DDB_G0274181 | Probable GH family 25 lysozyme 2; Belongs to the glycosyl hydrolase 25 family. (212 aa) |
| | Dd5P4 | Inositol 5-phosphatase 4. (787 aa) |
| | alyA | Lysozyme A; Has antibacterial activity against the Gram-positive bacteria B.subtilis, B.megaterium and M.luteus. No antibacterial activity detected against the Gram-positive bacterium S.aureus or against the Gram-negative bacterium E.coli. Lacks chitinase activity. (181 aa) |
| | alyC | Lysozyme C; Has antibacterial activity; Belongs to the dictyostelium lysozyme family. (181 aa) |
| | alyB | Lysozyme B; Has antibacterial activity; Belongs to the dictyostelium lysozyme family. (181 aa) |
| | DDB_G0276439 | Probable GH family 25 lysozyme 3; Belongs to the glycosyl hydrolase 25 family. (480 aa) |
| | vilA | Villidin; May function as a linker between membranes and the actin cytoskeleton. (1704 aa) |
| | dymA | Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway. (853 aa) |
| | gchA | GTP cyclohydrolase 1. (232 aa) |
| | rdiA | Putative rho GDP-dissociation inhibitor 1; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (By similarity). Regulates the Rac-dependent signaling pathways controlling cytokinesis, actin reorganization and the contractile vacuole. Required for efficient accumulation of cap at the cell cortex. (197 aa) |
| | pefA | Penta-EF hand domain-containing protein 1; Belongs to the Peflin/Sorcin family. (197 aa) |
| | racH | Rho-related protein racH. (200 aa) |
| | efa1B | Elongation factor 1-beta; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP; Belongs to the EF-1-beta/EF-1-delta family. (216 aa) |
| | dymB | Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (920 aa) |
| | atp1 | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (519 aa) |
| | noxA | Superoxide-generating NADPH oxidase heavy chain subunit A; Critical component of the membrane-bound oxidase that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity). (517 aa) |
| | lmpA | Lysosome membrane protein 2-A; May act as a lysosomal receptor (By similarity). May be involved in macropinocytosis and fluid phase exocytosis. Binds to the anionic phospholipid phosphoinositol 4,5-bisphosphate, but not to phosphatidylcholine and only weakly to phosphatidylserine. Belongs to the CD36 family. (779 aa) |
| | hspE-1 | Heat shock cognate 70 kDa protein 2; May function in protein folding and assembly, and disassembly of protein complexes. (632 aa) |
| | DDB_G0271242 | UPF0522 protein C. (503 aa) |
| | DDB0216762 | Uncharacterized protein. (220 aa) |
| | rpsA | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (245 aa) |
| | rasZ | Ras-like protein rasZ; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (214 aa) |
| | rasY | Ras-like protein rasY; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (216 aa) |
| | atg6A | Beclin-1-like protein A; Involved in autophagy. May be required to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the pre-autophagosomal structure (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. (1368 aa) |
| | DDB0190801 | Uncharacterized protein. (646 aa) |
| | DDB_G0269630 | TatD-related DNAse. (348 aa) |
| | DDB_G0269590 | P-type ATPase. (1386 aa) |
| | corB | Coronin-B; Involved in phagocytosis and cell motility. Binds to actin filaments and protects them against depolymerization. Belongs to the WD repeat coronin family. (962 aa) |
| | phg1a | Putative phagocytic receptor 1a; Involved in adhesion, phagocytosis of hydrophilic particles and intracellular killing of bacteria. Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface. Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (641 aa) |
| | PikF | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1382 aa) |
| | kil1 | Membrane-associated sulfotransferase kil1; Sulfotransferase involved in intracellular killing of bacteria; Belongs to the sulfotransferase 1 family. (471 aa) |
| | sodA | Superoxide dismutase [Cu-Zn] 1; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | cpiA | Cystatin-A1; Intracellular thiol proteinase inhibitor. Inhibits papain, but not cathepsin B. (94 aa) |
| | alrA | Aldose reductase A; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies (By similarity). Probably affects several metabolic pathways in addition to converting glucose to sorbitol. Affects group size; Belongs to the aldo/keto reductase family. (297 aa) |
| | poxA | Peroxinectin A; Belongs to the peroxidase family. (531 aa) |
| | aspS1 | Aspartate--tRNA ligase, cytoplasmic 1; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. (576 aa) |
| | vatB | V-type proton ATPase subunit B; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The B subunit is non- catalytic but combines with other subunits to form the catalytic complex. V-ATPase is responsible for energizing electrophoretic K(+)/2H(+) antiport by generating a transmembrane voltage of more than 200 mV (By similarity). (493 aa) |
| | p80 | Protein P80; Belongs to the SLC31A transporter family. (530 aa) |
| | cybA | Superoxide-generating NADPH oxidase light chain subunit; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. (118 aa) |
| | nramp1 | Metal transporter nramp1 homolog; Depletes iron from the phagolysosome in an ATP-dependent process. May rather act as a symporter of protons and metal cations in an ATP-dependent process. Nramp1 overexpression protected cells from L.pneumophila infection. (533 aa) |
| | DDB_G0274291 | Probable T4-type lysozyme 2. (170 aa) |
| | DDB0168980 | Saposin B-type domain-containing protein. (564 aa) |
