STRINGSTRING
tsuA tsuA pakC pakC DDB_G0286065 DDB_G0286065 mgp1 mgp1 DDB_G0293920 DDB_G0293920 pikB pikB pikA pikA rasC rasC abpC abpC arfA arfA pteN pteN sepA sepA qkgA-1 qkgA-1 forA forA DDB0205958 DDB0205958 mgp2 mgp2 pakD pakD phg2 phg2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tsuAProbable serine/threonine-protein kinase tsuA; Plays a role in chemotaxis and seems to be involved in polarization. (2247 aa)
pakCSerine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. (477 aa)
DDB_G0286065Uncharacterized ENTR1 family protein; Belongs to the ENTR1 family. (517 aa)
mgp1Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. (920 aa)
DDB_G0293920Uncharacterized protein. (861 aa)
pikBPhosphatidylinositol 3-kinase 2. (1857 aa)
pikAPhosphatidylinositol 3-kinase 1. (1571 aa)
rasCRas-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
abpCGelation factor; F-actin cross-linking protein. (857 aa)
arfAADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. (182 aa)
pteN3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] (533 aa)
sepASerine/threonine-protein kinase sepA; Serine/threonine-protein kinase involved in the spatial and temporal control system organizing cortical activities in mitotic and postmitotic cells. (1167 aa)
qkgA-1Probable serine/threonine-protein kinase qkgA; Involved in growth, and during development, in aggregation. (1553 aa)
forAFormin-A; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1218 aa)
DDB0205958Uncharacterized protein. (1333 aa)
mgp2Mental retardation GTPase activating protein homolog 2; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. (877 aa)
pakDSerine/threonine-protein kinase pakD. (1678 aa)
phg2Serine/threonine-protein kinase phg2; Serine/threonine kinase regulating cell substrate adhesion, phagocytosis, motility, chemotaxis, and actin cytoskeleton organization. It is a downstream component of Rap1-regulated adhesion, and it is a regulator of myosin II phosphorylation. It is also a negative regulator of development initiation. (1387 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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