node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abpC | qkgA-1 | P13466 | Q8SSS9 | Gelation factor; F-actin cross-linking protein. | Probable serine/threonine-protein kinase qkgA; Involved in growth, and during development, in aggregation. | 0.534 |
arfA | mgp1 | O00909 | Q54GD0 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. | 0.449 |
arfA | qkgA-1 | O00909 | Q8SSS9 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | Probable serine/threonine-protein kinase qkgA; Involved in growth, and during development, in aggregation. | 0.622 |
forA | pteN | Q54WH2 | Q8T9S7 | Formin-A; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | 0.408 |
mgp1 | arfA | Q54GD0 | O00909 | Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | 0.449 |
mgp1 | qkgA-1 | Q54GD0 | Q8SSS9 | Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. | Probable serine/threonine-protein kinase qkgA; Involved in growth, and during development, in aggregation. | 0.634 |
mgp1 | rasC | Q54GD0 | P32253 | Mental retardation GTPase activating protein homolog 1; Rho GTPase-activating protein involved in the signal transduction pathway (By similarity). Regulator of the contractile vacuole network as well as involved in driving vacuole emptying. | Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.469 |
pakC | pakD | Q55GV3 | Q55DD4 | Serine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. | Serine/threonine-protein kinase pakD. | 0.426 |
pakC | pteN | Q55GV3 | Q8T9S7 | Serine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | 0.469 |
pakD | pakC | Q55DD4 | Q55GV3 | Serine/threonine-protein kinase pakD. | Serine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. | 0.426 |
pakD | rasC | Q55DD4 | P32253 | Serine/threonine-protein kinase pakD. | Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.501 |
phg2 | rasC | Q54QQ1 | P32253 | Serine/threonine-protein kinase phg2; Serine/threonine kinase regulating cell substrate adhesion, phagocytosis, motility, chemotaxis, and actin cytoskeleton organization. It is a downstream component of Rap1-regulated adhesion, and it is a regulator of myosin II phosphorylation. It is also a negative regulator of development initiation. | Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.490 |
pikA | pikB | P54673 | P54674 | Phosphatidylinositol 3-kinase 1. | Phosphatidylinositol 3-kinase 2. | 0.930 |
pikA | pteN | P54673 | Q8T9S7 | Phosphatidylinositol 3-kinase 1. | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | 0.950 |
pikA | rasC | P54673 | P32253 | Phosphatidylinositol 3-kinase 1. | Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.495 |
pikB | pikA | P54674 | P54673 | Phosphatidylinositol 3-kinase 2. | Phosphatidylinositol 3-kinase 1. | 0.930 |
pikB | pteN | P54674 | Q8T9S7 | Phosphatidylinositol 3-kinase 2. | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | 0.940 |
pteN | forA | Q8T9S7 | Q54WH2 | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | Formin-A; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. | 0.408 |
pteN | pakC | Q8T9S7 | Q55GV3 | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | Serine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. | 0.469 |
pteN | pikA | Q8T9S7 | P54673 | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | Phosphatidylinositol 3-kinase 1. | 0.950 |