STRINGSTRING
RagC RagC DDB0186216 DDB0186216 DDB0186279 DDB0186279 DDB0186499 DDB0186499 DDB_G0285967 DDB_G0285967 gflB gflB DDB_G0286931 DDB_G0286931 secG secG wdr24 wdr24 cnrN cnrN p2xE p2xE dst4 dst4 p2xD p2xD ragA ragA DDB0216036 DDB0216036 DDB0188195 DDB0188195 gefA gefA pdkB pdkB DDB0219551 DDB0219551 DDB0219603 DDB0219603 mapbpip mapbpip dst3 dst3 DDB_G0291510 DDB_G0291510 DDB_G0291948 DDB_G0291948 racGAP racGAP DDB0184177 DDB0184177 sec13 sec13 DDB_G0292056 DDB_G0292056 DDB_G0292252 DDB_G0292252 lst8 lst8 DDB0191697 DDB0191697 DDB0191741 DDB0191741 racE racE DDB_G0292160 DDB_G0292160 pikB pikB pikA pikA pkbA pkbA gskA gskA gpbA gpbA carC carC gpaD gpaD rasC rasC pkgB pkgB rapA rapA gpaB gpaB rasG rasG carA-1 carA-1 pkaR pkaR piaA piaA krsA krsA ripA ripA myoM myoM rdiA rdiA rdiB rdiB pteN pteN DDB0168530 DDB0168530 gefM gefM gbpC gbpC pdeD pdeD gefB gefB gefH gefH DDB0168842 DDB0168842 DDB0169145 DDB0169145 p2xA p2xA DDB_G0274833 DDB_G0274833 dst1 dst1 ctnA ctnA DDB0217806 DDB0217806 pakB pakB rapgap1 rapgap1 pakC pakC DDB_G0267588 DDB_G0267588 DDB0189538 DDB0189538 krsB krsB DDB_G0269450 DDB_G0269450 DDB0190465 DDB0190465 pakD pakD pakA pakA mpl2 mpl2 mpl1 mpl1 DDB_G0271288 DDB_G0271288 nfaA nfaA DDB_G0271806 DDB_G0271806 DDB_G0273199 DDB_G0273199 bip1-1 bip1-1 DDB0168059 DDB0168059 pakH-1 pakH-1 p2xB p2xB p2xC p2xC DDB0217695 DDB0217695 med26 med26 GxcN GxcN rheb rheb DDB_G0277071 DDB_G0277071 racgef1 racgef1 gacII gacII mpl3 mpl3 DDB0205477 DDB0205477 ngap ngap scaA scaA DDB_G0279099 DDB_G0279099 DDB0205671 DDB0205671 gacN gacN DDB_G0279427 DDB_G0279427 yju2 yju2 STK19 STK19 DDB0206467 DDB0206467 DDB0218242 DDB0218242 DDB_G0280947 DDB_G0280947 DDB_G0280955 DDB_G0280955 DDB0204021 DDB0204021 far1 far1 pdkA pdkA DDB_G0281809 DDB_G0281809 DDB0205121 DDB0205121 rapgapB rapgapB DDB0204990 DDB0204990 pakG pakG DDB0185275 DDB0185275 DDB0218425 DDB0218425 dhkL dhkL gpaI gpaI DDB_G0283567 DDB_G0283567 gacG gacG DDB0185814 DDB0185814 dhkG dhkG
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
RagCUncharacterized protein. (360 aa)
DDB0186216Rap-GAP domain-containing protein. (1640 aa)
DDB0186279Uncharacterized protein. (759 aa)
DDB0186499Uncharacterized protein. (746 aa)
DDB_G0285967LIM-type zinc finger-containing protein. (998 aa)
gflBRas guanine nucleotide exchange factor glfB; GpaB-activated, rapA-specific guanine nucleotide exchange factor, involved in the regulation of the balance between Ras and Rap signaling at the leading edge of chemotaxing cells. Spatially localized activation of Rap and Ras induces F-actin polymerization at the leading edge of chemotaxing cells through the Rac, PI3K, and TORC2 pathways. Acts also as a key regulator of actin-driven membrane protrusions during processes such as phagocytosis and cytokinesis, possibly by modulating rapA signaling pathways. (1601 aa)
DDB_G0286931Uncharacterized protein. (5222 aa)
secGAnkyrin repeat, PH and SEC7 domain containing protein secG. (986 aa)
wdr24GATOR complex protein WDR24; As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway. (1023 aa)
cnrNPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells. (639 aa)
p2xEP2X receptor E; P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Not essential for osmoregulation. Inward currents evoked by intracellular ATP. ATP analog beta, gamma-imido-ATP is a weak partial agonist of p2xE. Exclusively selective for ATP over other nucleotides. Insensitive to copper and P2 receptor antagonists PPADS and suramin but strongly inhibited by sodium ions. More permeable to ammonium than either sodium or potassium ions and less permeable to choline. Permeabl [...] (388 aa)
dst4Serine/threonine-protein kinase dst4. (485 aa)
p2xDP2X receptor D; P2X receptors are ligand-gated ion channels that play a role in intracellular calcium signaling. ATP does not evoke inward currents in p2xD. Not essential for osmoregulation. (407 aa)
ragARas-related GTP-binding protein A; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the TOR signaling cascade; Belongs to the GTR/RAG GTP-binding protein family. (301 aa)
DDB0216036Rab-GAP TBC domain-containing protein. (463 aa)
DDB0188195Ras-GAP domain-containing protein. (817 aa)
gefARas guanine nucleotide exchange factor A; Ras-bound GDP/GTP exchange factor required for normal activation of adenylyl cyclase. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. (605 aa)
pdkB3-phosphoinositide-dependent protein kinase B. (908 aa)
DDB0219551SEC7 domain-containing protein. (1886 aa)
DDB0219603SEC7 domain-containing protein. (1748 aa)
mapbpipRobl_LC7 domain-containing protein. (123 aa)
dst3Serine/threonine-protein kinase dst3. (562 aa)
DDB_G0291510GTPase-activating protein DDB_G0291510. (1031 aa)
DDB_G0291948Ragulator complex protein LAMTOR4 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). (87 aa)
racGAPUncharacterized protein. (1350 aa)
DDB0184177Uncharacterized protein. (437 aa)
sec13Protein SEC13 homolog; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 [...] (301 aa)
DDB_G0292056WD repeat-containing protein DDB_G0292056. (1823 aa)
DDB_G0292252Putative protein DDB_G0292252. (1256 aa)
lst8Protein LST8 homolog; Plays a role in regulation of adenylate cyclase and protein kinase B (PKB) activation during aggregation. Involved in both chemotaxis and signal relay; Belongs to the WD repeat LST8 family. (304 aa)
DDB0191697Uncharacterized protein. (453 aa)
DDB0191741Uncharacterized protein. (716 aa)
racERho-related protein racE; Specifically required for cytokinesis; Belongs to the small GTPase superfamily. Rho family. (223 aa)
DDB_G0292160Uncharacterized protein DDB_G0292160. (174 aa)
pikBPhosphatidylinositol 3-kinase 2. (1857 aa)
pikAPhosphatidylinositol 3-kinase 1. (1571 aa)
pkbARAC family serine/threonine-protein kinase homolog; Predominantly involved during the aggregation to control cell polarity and chemotaxis. Phosphorylates talB, gefN, gefS, PI4P 5-kinase and gacQ. (444 aa)
gskAGlycogen synthase kinase-3; During cellular differentiation, may mediate an extracellular cyclic AMP stimulated signal transduction pathway that regulates prespore and prestalk B-cell proportions through inhibition of stalk cell formation and induction of prespore cell differentiation. The cAMP receptor carC appears to activate gskA via the tyrosine kinases zakA and zak2, to stimulate prespore differentiation, while carD appears to negatively regulate gskA, to promote prestalk formation. (467 aa)
gpbAGuanine nucleotide-binding protein subunit beta; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). Required for normal chemotaxis in response to cAMP and for aggregation during scorocarp development. (347 aa)
carCCyclic AMP receptor 3; Receptor for cAMP. Coordinates the aggregation of individual cells into a multicellular organism and regulates the expression of a large number of developmentally regulated genes. The activity of this receptor is mediated by G proteins; Belongs to the G-protein coupled receptor 5 family. (490 aa)
gpaDGuanine nucleotide-binding protein alpha-4 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-4 plays a role in morphogenesis of the multicellular structure. (345 aa)
rasCRas-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
pkgBProtein kinase 2; Required for morphogenesis during multicellular development. Phosphorylates talB, gefN, gefS, PI4P 5-kinase and gacQ. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (479 aa)
rapARas-related protein rapA; G protein of the Ras family that positively regulates phagocytosis and negatively regulates macropinocytosis. May be involved in the activation of guanylyl cyclase during the response to hyperosmotic conditions. Overexpressing cells generate alterations in cell shape and contractile responses. Involved in chemotaxis via regulation of the balance of Ras and Rap signaling at the leading edge of chemotaxing cells. (186 aa)
gpaBGuanine nucleotide-binding protein alpha-2 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-2 is required for the early aggregation process and most of the known cAMP receptor-mediated responses. Interacts with downstream effector gflB, a Rap guanine nucleotide exchange factor, to regulate the balance between Ras and Rap signaling at the leading edge of chemotaxing cells. Belongs to the G-alpha family. (357 aa)
rasGRas-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
carA-1Cyclic AMP receptor 1; Receptor for cAMP. Coordinates the aggregation of individual cells into a multicellular organism and regulates the expression of a large number of developmentally regulated genes. The activity of this receptor is mediated by G proteins. (392 aa)
pkaRcAMP-dependent protein kinase regulatory subunit. (327 aa)
piaAProtein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] (1148 aa)
krsASerine/threonine-protein kinase 4 homolog A; Regulates both cAMP signaling during early development and the stress response. Functions as an activator of adenylylcyclase. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (461 aa)
ripARas-interacting protein RIP3; Component of a Ras-regulated pathway involved in integrating chemotaxis and signal relay pathways that are essential for aggregation. (838 aa)
myoMMyosin-M heavy chain; Myosins are actin-based motor molecules with ATPase activity. Involved in macropinocytosis and remodeling of actin cytoskeleton. (1737 aa)
rdiAPutative rho GDP-dissociation inhibitor 1; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (By similarity). Regulates the Rac-dependent signaling pathways controlling cytokinesis, actin reorganization and the contractile vacuole. Required for efficient accumulation of cap at the cell cortex. (197 aa)
rdiBPutative rho GDP-dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. (152 aa)
pteN3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] (533 aa)
DDB0168530Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (560 aa)
gefMRas guanine nucleotide exchange factor M; Promotes the exchange of Ras-bound GDP by GTP. (929 aa)
gbpCCyclic GMP-binding protein C; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Required for cyclic GMP-mediated chemotaxis, polarity. Plays a key role in cyclic AMP-induced myosin II translocation to the cortex. Also involved in the phosphorylation of mlkA and mlcR, either directly or via an intermediate kinase. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. (2631 aa)
pdeDcGMP-dependent 3',5'-cGMP phosphodiesterase A; Phosphodiesterase specific for cGMP, which is activated by cGMP but not by cAMP. Involved in the degradation of intracellular cGMP. (867 aa)
gefBRas guanine nucleotide exchange factor B; Promotes the exchange of Ras-bound GDP by GTP (By similarity). Involved in phagocytosis, fluid-phase endocytosis, regulation of macropinocytosis and control of cell movement. (1529 aa)
gefHRas guanine nucleotide exchange factor H; Promotes the exchange of Ras-bound GDP by GTP. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. (604 aa)
DDB0168842Uncharacterized protein. (931 aa)
DDB0169145Uncharacterized protein; Belongs to the WD repeat SEC13 family. (467 aa)
p2xAP2X receptor A; P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Inward currents evoked by intracellular ATP and ATP analogs. Exclusively selective for ATP over other nucleotides. Insensitive to P2 receptor antagonists PPADS, suramin and 2',3'-O-(2,4,6-trinitrophenyl)-ATP but inhibited by nanomolar concentrations of copper and sodium ion. More permeable to ammonium than either sodium or potassium ions and less permeable to choline. It has been reported that p2xA is not es [...] (378 aa)
DDB_G0274833Ragulator complex protein LAMTOR3 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. May activate the TOR signaling cascade in response to amino acids (By similarity); Belongs to the LAMTOR3 family. (132 aa)
dst1Serine/threonine-protein kinase dst1. (737 aa)
ctnACountin-1; Cell-counting factor that limits the maximum size of the multicellular structure. May down-regulate the expression of gp24, which mediates cell adhesion. (258 aa)
DDB0217806Rap-GAP domain-containing protein. (855 aa)
pakBSerine/threonine-protein kinase pakB; Regulator of the myosin I component of the cytoskeleton: required for regulation of cytokinesis, phagocytosis and pinocytosis. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (852 aa)
rapgap1RapA guanosine triphosphatase-activating protein 1; Mediates the deactivation of rap1 and plays an important role in spatially and temporally regulating cell adhesion and chemotaxis by controlling attachment disassembly in the leading edge through the regulation of myosin II assembly and disassembly. Overexpression leads to defective chemotaxis. (1055 aa)
pakCSerine/threonine-protein kinase pakC; Has role in the regulation of chemotaxis. (477 aa)
DDB_G0267588Probable phosphatidylinositol phosphate kinase DDB_G0267588; May be involved in signaling events that underlie chemotaxis via the chemoattractant-mediated pkgB phosphorylation. (719 aa)
DDB0189538Uncharacterized protein. (1426 aa)
krsBSerine/threonine-protein kinase 4 homolog B; Probable serine/threonine-protein kinase; In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (1105 aa)
DDB_G0269450AKAP7_NLS domain-containing protein. (206 aa)
DDB0190465Uncharacterized protein. (925 aa)
pakDSerine/threonine-protein kinase pakD. (1678 aa)
pakASerine/threonine-protein kinase pakA; Regulator of the myosin II component of the cytoskeleton: required for regulation of cytokinesis. Functions during chemotaxis, required for maintaining the direction of cell movement, suppressing lateral pseudopod extension, and proper retraction of the posterior of chemotaxing cells; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (1197 aa)
mpl2MAP kinase phosphatase with leucine-rich repeats protein 2; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (695 aa)
mpl1MAP kinase phosphatase with leucine-rich repeats protein 1; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins (By similarity). Dephosphorylates pNPP, in vitro. Essential for proper regulation of erkB (erk2) and optimal motility during development; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (834 aa)
DDB_G0271288NPR2 family protein. (392 aa)
nfaANeurofibromin-A; Regulator of the GTPase activity of Ras, mainly RasG and RasB. (920 aa)
DDB_G0271806PH and Rap-GAP domain-containing protein DDB_G0271806. (1167 aa)
DDB_G0273199Probable rhodanese domain-containing dual specificity protein phosphatase; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (476 aa)
bip1-1Luminal-binding protein 1; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER; Belongs to the heat shock protein 70 family. (926 aa)
DDB0168059SEC7 domain-containing protein. (2048 aa)
pakH-1Serine/threonine-protein kinase pakH; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (513 aa)
p2xBP2X receptor B; P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Not essential for osmoregulation. Inward currents are evoked by intracellular ATP and ATP analogs. Insensitive to the P2 receptor antagonists PPADS and suramin, and also copper ions. Inhibited by sodium ions. Permeable to chloride ions. (369 aa)
p2xCP2X receptor C; P2X receptors are ligand-gated ion channels that play a role in intracellular calcium signaling. ATP does not evoke inward currents in p2xC. Not essential for osmoregulation. (368 aa)
DDB0217695Uncharacterized protein. (527 aa)
med26Putative mediator of RNA polymerase II transcription subunit 26; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (2073 aa)
GxcNUncharacterized protein. (1094 aa)
rhebGTP-binding protein Rheb homolog; Binds GTP and exhibits intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rheb family. (185 aa)
DDB_G0277071Probable serine/threonine-protein kinase DDB_G0277071. (2454 aa)
racgef1Rac guanyl-nucleotide exchange factor. (1218 aa)
gacIIRho GTPase-activating protein gacII; Rho GTPase-activating protein involved in the signal transduction pathway. (817 aa)
mpl3MAP kinase phosphatase with leucine-rich repeats protein 3; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (856 aa)
DDB0205477Uncharacterized protein. (601 aa)
ngapProbable Ras GTPase-activating-like protein ngap; May function as a Ras GTPase-activating protein. (877 aa)
scaASca1 complex scaffold protein scaA; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. ScaA acts as a molecular scaffold, bringing together gefA, gefH and phr with PP2A. (1582 aa)
DDB_G0279099DEP domain-containing protein DDB_G0279099; In the N-terminal section; belongs to the IML1 family. (2242 aa)
DDB0205671Uncharacterized protein. (919 aa)
gacNRho GTPase-activating protein gacN; Rho GTPase-activating protein involved in the signal transduction pathway. (611 aa)
DDB_G0279427Sestrin homolog; May function as a negative feedback regulator of TOR function; Belongs to the sestrin family. (601 aa)
yju2Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. (324 aa)
STK19Serine/threonine-protein kinase 19 homolog; Serine/threonine-protein kinase. (391 aa)
DDB0206467Uncharacterized protein. (298 aa)
DDB0218242Rap-GAP domain-containing protein. (2935 aa)
DDB_G0280947UPF0171 family protein. (718 aa)
DDB_G0280955RabGAP/TBC domain-containing protein. (733 aa)
DDB0204021UDENN FLCN/SMCR8-type domain-containing protein. (656 aa)
far1Metabotropic glutamate receptor-like protein L; In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily. (708 aa)
pdkAProbable serine/threonine-protein kinase pdkA. (686 aa)
DDB_G0281809Rap-GAP domain-containing protein DDB_G0281809. (1619 aa)
DDB0205121Uncharacterized protein. (464 aa)
rapgapBRapA guanosine triphosphatase-activating protein B; Mediates the deactivation of rap1 during multicellular development and is required for normal morphogenesis. Also required for the correct patterning of specific subtypes of prestalk cells. (418 aa)
DDB0204990Cnn_1N domain-containing protein. (1381 aa)
pakGSerine/threonine-protein kinase pakG. (1179 aa)
DDB0185275Rap-GAP domain-containing protein. (1069 aa)
DDB0218425Rap-GAP domain-containing protein. (1049 aa)
dhkLHybrid signal transduction histidine kinase L; Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity). (1709 aa)
gpaIGuanine nucleotide-binding protein alpha-9 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-9 antagonizes broad chemotactic response. It functions rapidly following receptor stimulation to negatively regulate PI3K/PTEN, adenylyl cyclase, and guanylyl cyclase pathways. (342 aa)
DDB_G0283567Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). (89 aa)
gacGRho GTPase-activating protein gacG; Rho GTPase-activating protein involved in the signal transduction pathway. (1312 aa)
DDB0185814Rap-GAP domain-containing protein. (366 aa)
dhkGHybrid signal transduction histidine kinase G; Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity). (3432 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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