Probable serine/threonine-protein kinase DDB_G0288147; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

Extracellular signal-regulated kinase 1; Kinase involved in a signal transduction pathway.

Probable serine/threonine-protein kinase DDB_G0288147; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.

Probable serine/threonine-protein kinase DDB_G0288147; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

Ras-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.

PNPLA domain-containing protein.

Serine/threonine-protein kinase pakD.

PNPLA domain-containing protein.

Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...]

Counting factor associated protein D; Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Counting factor associated protein D; Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.

Guanine nucleotide-binding protein alpha-8 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-8 is a potential analog for the G(s)-like G-proteins which stimulate adenylate cyclase in mammals.

Counting factor associated protein D; Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.

Metabotropic glutamate receptor-like protein H; In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.

Counting factor associated protein D; Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.

Serine/threonine-protein kinase pakD.

Counting factor associated protein D; Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.

Retinoblastoma-like protein A; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin- modifying enzymes to promoters (By similarity). Plays a dual role, regulating cell-cycle progression and transcriptional events leading to terminal differentiation. In the absence of a G1 phase, functions in late G2 contro [...]

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Counting factor associated protein D; Inhibitor that slows proliferation of secreting cells (also known as chalone). Requires aprA for activity.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Guanine nucleotide-binding protein alpha-8 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G alpha-8 is a potential analog for the G(s)-like G-proteins which stimulate adenylate cyclase in mammals.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Metabotropic glutamate receptor-like protein H; In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Serine/threonine-protein kinase pakD.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

RAC family serine/threonine-protein kinase homolog; Predominantly involved during the aggregation to control cell polarity and chemotaxis. Phosphorylates talB, gefN, gefS, PI4P 5-kinase and gacQ.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Ras-like protein rasC; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Ras-like protein rasG; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN; Protein phosphatase that negatively regulates PI3K-dependent pathways. Regulates cAMP signal transduction to control territory size. During development, a lawn of Dictyostelium cells breaks up into territories where cells aggregate in dendritic streams to form groups of 20'000 cells.

Retinoblastoma-like protein A; Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin- modifying enzymes to promoters (By similarity). Plays a dual role, regulating cell-cycle progression and transcriptional events leading to terminal differentiation. In the absence of a G1 phase, functions in late G2 contro [...]

Extracellular signal-regulated kinase 1; Kinase involved in a signal transduction pathway.

Probable serine/threonine-protein kinase DDB_G0288147; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

Extracellular signal-regulated kinase 1; Kinase involved in a signal transduction pathway.

Guanine nucleotide-binding protein subunit beta; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). Required for normal chemotaxis in response to cAMP and for aggregation during scorocarp development.