STRINGSTRING
myoB myoB DDB0190636 DDB0190636 DDB0202870 DDB0202870 mlcB mlcB DDB0184538 DDB0184538 myoH myoH mlcR mlcR mlcE mlcE mhcA mhcA DDB_G0291396 DDB_G0291396 myoD myoD DDB0167176 DDB0167176 myoG myoG mlcD mlcD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
myoBMyosin IB heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Myosin IB may have a role in chemotaxis and aggregation; it could serve to stabilize and even retract cortical structures, such as pseudopods and lamellopods. Involved in the whole cell motility of aggregation-stages cells. Overexpression results in significant decrease in the rate of cellular translocation and fluid-phase pinocytosis and abnormalities in the normal rearrangement of the actin cytoskeleton. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myos [...] (1111 aa)
DDB0190636SH3 domain-containing protein. (364 aa)
DDB0202870Uncharacterized protein. (1505 aa)
mlcBMyosin-IB light chain; Functions as the light chain for myosin-B. Binds calcium with submicromolar affinity and may sense physiological calcium changes. (73 aa)
DDB0184538Uncharacterized protein. (879 aa)
myoHMyosin-H heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1771 aa)
mlcRMyosin regulatory light chain. (161 aa)
mlcEMyosin, essential light chain. (150 aa)
mhcAMyosin-2 heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa)
DDB_G0291396Dilute domain-containing protein. (968 aa)
myoDMyosin ID heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Myosin id may have a role in chemotaxis and aggregation; it could serve to stabilize and even retract cortical structures, such as pseudopods and lamellopods. Involved in the process of phagocytosis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1109 aa)
DDB0167176Uncharacterized protein. (1130 aa)
myoGMyosin-G heavy chain; Myosins are actin-based motor molecules with ATPase activity. (3446 aa)
mlcDMyosin-ID light chain; Functions as the light chain for myosin-D. Has low affinity for calcium. (147 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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