(16 nodes) 90S preribosome network (Dictyostelium discoideum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDB0217650	CBF domain-containing protein. (712 aa)
	Wdr36	Uncharacterized protein. (1026 aa)
	DDB_G0278251	Uncharacterized protein. (131 aa)
	DDB0190597	RRP7 domain-containing protein. (496 aa)
	Utp18	Uncharacterized protein. (520 aa)
	Imp3	S4 RNA-binding domain-containing protein. (177 aa)
	Mpp10	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (765 aa)
	utp6	U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family. (609 aa)
	DDB_G0281839	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (833 aa)
	wdr3	WD repeat-containing protein 3 homolog. (942 aa)
	DDB0185982	Uncharacterized protein. (802 aa)
	pwp2	Periodic tryptophan protein 2 homolog. (922 aa)
	Nop14	Uncharacterized protein. (984 aa)
	DDB_G0289415	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (678 aa)
	Nol6	Uncharacterized protein. (1278 aa)
	imp4	U3 small nucleolar ribonucleoprotein protein. (286 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0185982	DDB0190597	Q54PQ6	Q55D06	Uncharacterized protein.	RRP7 domain-containing protein.	0.797
DDB0185982	DDB0217650	Q54PQ6	Q553S0	Uncharacterized protein.	CBF domain-containing protein.	0.919
DDB0185982	DDB_G0278251	Q54PQ6	Q54YG1	Uncharacterized protein.	Uncharacterized protein.	0.985
DDB0185982	DDB_G0281839	Q54PQ6	Q54TD8	Uncharacterized protein.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.985
DDB0185982	DDB_G0289415	Q54PQ6	Q54HJ2	Uncharacterized protein.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.997
DDB0185982	Imp3	Q54PQ6	Q54XG2	Uncharacterized protein.	S4 RNA-binding domain-containing protein.	0.795
DDB0185982	Mpp10	Q54PQ6	Q54X28	Uncharacterized protein.	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family.	0.890
DDB0185982	Nol6	Q54PQ6	Q54EN2	Uncharacterized protein.	Uncharacterized protein.	0.971
DDB0185982	Nop14	Q54PQ6	Q54K79	Uncharacterized protein.	Uncharacterized protein.	0.949
DDB0185982	Utp18	Q54PQ6	Q55BA1	Uncharacterized protein.	Uncharacterized protein.	0.897
DDB0185982	Wdr36	Q54PQ6	Q550V0	Uncharacterized protein.	Uncharacterized protein.	0.953
DDB0185982	imp4	Q54PQ6	C7G018	Uncharacterized protein.	U3 small nucleolar ribonucleoprotein protein.	0.905
DDB0185982	pwp2	Q54PQ6	Q54PE0	Uncharacterized protein.	Periodic tryptophan protein 2 homolog.	0.960
DDB0185982	utp6	Q54PQ6	Q54WN5	Uncharacterized protein.	U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family.	0.880
DDB0185982	wdr3	Q54PQ6	Q54S79	Uncharacterized protein.	WD repeat-containing protein 3 homolog.	0.943
DDB0190597	DDB0185982	Q55D06	Q54PQ6	RRP7 domain-containing protein.	Uncharacterized protein.	0.797
DDB0190597	DDB0217650	Q55D06	Q553S0	RRP7 domain-containing protein.	CBF domain-containing protein.	0.990
DDB0190597	DDB_G0278251	Q55D06	Q54YG1	RRP7 domain-containing protein.	Uncharacterized protein.	0.707
DDB0190597	DDB_G0281839	Q55D06	Q54TD8	RRP7 domain-containing protein.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.700
DDB0190597	DDB_G0289415	Q55D06	Q54HJ2	RRP7 domain-containing protein.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.715