STRINGSTRING
mhcA mhcA myoA myoA myoB myoB myoD myoD myoC myoC myoF myoF myoH myoH myoJ myoJ myoE myoE myoG myoG myoM myoM myoI myoI myoK myoK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mhcAMyosin-2 heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa)
myoAMyosin IA heavy chain; Actin-based motor protein, possibly involved in a wide range of motile processes, such as cell movement across a surface, and extension and retraction of pseudopodia or lamellipodia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (994 aa)
myoBMyosin IB heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Myosin IB may have a role in chemotaxis and aggregation; it could serve to stabilize and even retract cortical structures, such as pseudopods and lamellopods. Involved in the whole cell motility of aggregation-stages cells. Overexpression results in significant decrease in the rate of cellular translocation and fluid-phase pinocytosis and abnormalities in the normal rearrangement of the actin cytoskeleton. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myos [...] (1111 aa)
myoDMyosin ID heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Myosin id may have a role in chemotaxis and aggregation; it could serve to stabilize and even retract cortical structures, such as pseudopods and lamellopods. Involved in the process of phagocytosis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1109 aa)
myoCMyosin IC heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. Involved in the process of phagocytosis and appears to support streaming behavior. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1182 aa)
myoFMyosin IF heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1071 aa)
myoHMyosin-H heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1771 aa)
myoJMyosin-J heavy chain; Processive motor protein that can move over long distances along F-actin without disassociating; processiveness depends on high physiological Mg(2+) concentrations. Presents a high actin affinity in the presence of ADP, fast ATP hydrolysis, and a high steady-state ATPase activity in the presence of actin that is rate limited by ADP release. Physiological decrease of free Mg(2+) ions leads to an increased rate of ADP release and shortening of the fraction of time it spends in the strong acting binding states. (2245 aa)
myoEMyosin IE heavy chain; Myosin is a protein that binds to actin and has ATPase activity that is activated by actin. May play a role in moving membranes relative to actin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1005 aa)
myoGMyosin-G heavy chain; Myosins are actin-based motor molecules with ATPase activity. (3446 aa)
myoMMyosin-M heavy chain; Myosins are actin-based motor molecules with ATPase activity. Involved in macropinocytosis and remodeling of actin cytoskeleton. (1737 aa)
myoIMyosin-I heavy chain; Myosins are actin-based motor molecules with ATPase activity. Involved in the early steps of phagocytosis and adhesion. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2357 aa)
myoKMyosin-K heavy chain; Myosins are actin-based motor molecules with ATPase activity. Involved in phagocytosis and motility, and in the maintenance and dynamics of cell cortex; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (858 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.