STRINGSTRING
DDB0204632 DDB0204632 DDB0185712 DDB0185712 abnA abnA abnB abnB DDB0190490 DDB0190490 WipA WipA DDB_G0292878 DDB_G0292878 limD limD scrA scrA slob2 slob2 slob1 slob1 wasA wasA DDB_G0272811 DDB_G0272811 vasp vasp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDB0204632WH2 domain-containing protein. (459 aa)
DDB0185712Uncharacterized protein. (905 aa)
abnAActobindin-A; Is able to bind two actin monomers at high concentrations of G-actin. Inhibits actin polymerization by sequestering G-actin and stabilizing actin dimers (By similarity). (92 aa)
abnBActobindin-B/C; Is able to bind two actin monomers at high concentrations of G-actin. Inhibits actin polymerization by sequestering G-actin and stabilizing actin dimers (By similarity). (90 aa)
DDB0190490Uncharacterized protein. (305 aa)
WipAWH2 domain-containing protein. (197 aa)
DDB_G0292878WAS protein family homolog DDB_G0292878; Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization. (472 aa)
limDLIM domain protein. (700 aa)
scrAProtein SCAR; Involved in regulation of actin and microtubule organization. Regulates phagocytosis and macropinocytosis. Belongs to the SCAR/WAVE family. (443 aa)
slob2Probable inactive serine/threonine-protein kinase slob2; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (574 aa)
slob1Probable inactive serine/threonine-protein kinase slob1. (585 aa)
wasAWiscott-Aldrich syndrome protein. (399 aa)
DDB_G0272811WASP-related protein. (583 aa)
vaspProtein VASP homolog; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as lamellipodial and filopodial dynamics in migrating cells. Plays a crucial role in filopodia formation, cell-substratum adhesion, and proper chemotaxis. Nucleates and bundles actin filaments. When complexed with fotH in filopodial tips, may support formin- mediated filament elongation by bundling nascent actin filaments. Belongs to the Ena/VASP family. (380 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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