(15 nodes) Protein-tyrosine phosphatase, catalytic network (Dictyostelium discoideum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ptpC	Tyrosine-protein phosphatase 3; Seems to dephosphorylate a protein of 130 kDa (p130). (990 aa)
	ptpA1-1	Tyrosine-protein phosphatase 1; May have a role in growth and in the early stages of development. Affects the timing of development; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (522 aa)
	DDB_G0292024	Probable protein tyrosine phosphatase type IVA A; Belongs to the protein-tyrosine phosphatase family. (166 aa)
	DDB_G0290005	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. (1324 aa)
	DDB_G0285967	LIM-type zinc finger-containing protein. (998 aa)
	DDB0186027	Myotubularin phosphatase domain-containing protein. (1028 aa)
	DDB0204242	Myotubularin phosphatase domain-containing protein. (1343 aa)
	mpl3	MAP kinase phosphatase with leucine-rich repeats protein 3; Probable phosphatase with dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (856 aa)
	DDB0205364	Myotubularin phosphatase domain-containing protein. (1002 aa)
	DDB0217695	Uncharacterized protein. (527 aa)
	DDB_G0273199	Probable rhodanese domain-containing dual specificity protein phosphatase; Has a dual specificity toward Ser/Thr and Tyr-containing proteins; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (476 aa)
	DDB_G0272662	Probable protein tyrosine phosphatase type IVA B; Belongs to the protein-tyrosine phosphatase family. (163 aa)
	DDB0191697	Uncharacterized protein. (453 aa)
	DDB_G0288731	GRAM domain-containing protein. (1227 aa)
	ptpB	Tyrosine-protein phosphatase 2. (377 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0186027	DDB0204242	Q54PL3	Q54TD5	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0186027	DDB0205364	Q54PL3	Q54YC2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.502
DDB0186027	DDB_G0288731	Q54PL3	Q1ZXD2	Myotubularin phosphatase domain-containing protein.	GRAM domain-containing protein.	0.497
DDB0186027	DDB_G0290005	Q54PL3	Q54GQ1	Myotubularin phosphatase domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.518
DDB0191697	DDB_G0285967	Q54CH3	Q54MG8	Uncharacterized protein.	LIM-type zinc finger-containing protein.	0.913
DDB0204242	DDB0186027	Q54TD5	Q54PL3	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.503
DDB0204242	DDB0205364	Q54TD5	Q54YC2	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.496
DDB0204242	DDB_G0288731	Q54TD5	Q1ZXD2	Myotubularin phosphatase domain-containing protein.	GRAM domain-containing protein.	0.508
DDB0204242	DDB_G0290005	Q54TD5	Q54GQ1	Myotubularin phosphatase domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.525
DDB0205364	DDB0186027	Q54YC2	Q54PL3	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.502
DDB0205364	DDB0204242	Q54YC2	Q54TD5	Myotubularin phosphatase domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.496
DDB0205364	DDB_G0288731	Q54YC2	Q1ZXD2	Myotubularin phosphatase domain-containing protein.	GRAM domain-containing protein.	0.502
DDB0205364	DDB_G0290005	Q54YC2	Q54GQ1	Myotubularin phosphatase domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.517
DDB0217695	DDB_G0285967	Q553B4	Q54MG8	Uncharacterized protein.	LIM-type zinc finger-containing protein.	0.838
DDB_G0285967	DDB0191697	Q54MG8	Q54CH3	LIM-type zinc finger-containing protein.	Uncharacterized protein.	0.913
DDB_G0285967	DDB0217695	Q54MG8	Q553B4	LIM-type zinc finger-containing protein.	Uncharacterized protein.	0.838
DDB_G0288731	DDB0186027	Q1ZXD2	Q54PL3	GRAM domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.497
DDB_G0288731	DDB0204242	Q1ZXD2	Q54TD5	GRAM domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.508
DDB_G0288731	DDB0205364	Q1ZXD2	Q54YC2	GRAM domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.502
DDB_G0288731	DDB_G0290005	Q1ZXD2	Q54GQ1	GRAM domain-containing protein.	Myotubularin-related protein DDB_G0290005; Phosphatase that acts on lipids with a phosphoinositol headgroup; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.	0.523