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| | DDB0202825 | Uncharacterized protein. (1461 aa) |
| | DDB0216942 | Uncharacterized protein. (505 aa) |
| | DDB_G0272456 | Putative uncharacterized protein DDB_G0272456. (1521 aa) |
| | gefL | Ras guanine nucleotide exchange factor L; Promotes the exchange of Ras-bound GDP by GTP. (2356 aa) |
| | DDB_G0295775 | Armadillo-like helical domain-containing protein. (332 aa) |
| | DDB_G0284307 | Mo25-like family protein. (363 aa) |
| | DDB_G0286969 | Von Willebrand factor A domain-containing protein DDB_G0286969. (2079 aa) |
| | taf2 | Transcription initiation factor TFIID subunit. (2044 aa) |
| | darA | Darlin; Part of a signaling pathway that initiates the aggregation and leads to the formation of aggregation centers or streams. Not essential for cytokinesis, pinocytosis or phagocytosis. Not essential for development, except in starvation-induced aggregation. Belongs to the RAP1GDS1 family. (766 aa) |
| | piaA | Protein pianissimo A; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Required for chemoattractant receptor and G protein- mediated activation of the 12 transmembrane domain adenylyl cyclase. Functions as a part of protein complex TORC2. TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2, but not TORC1, negatively regulates phagocytosis. This protein and dagA protein CRAC, a cytosolic regulator, are both essential for activation of the enzyme adenylyl cyclase. This protein and CRAC do not function re [...] (1148 aa) |
| | chcA | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. (1694 aa) |
| | lkhA | Leucine aminopeptidase; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro). (606 aa) |
| | pikA | Phosphatidylinositol 3-kinase 1. (1571 aa) |
| | pikB | Phosphatidylinositol 3-kinase 2. (1857 aa) |
| | pikC | Phosphatidylinositol 3-kinase 3. (1697 aa) |
| | pikE | Phosphatidylinositol 3-kinase VPS34-like. (816 aa) |
| | pikD | Phosphatidylinositol 4-kinase; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate; Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. (1180 aa) |
| | forG | Formin-G; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1074 aa) |
| | mtaA | Centrosomal protein 224; Involved in regulation of microtubule dynamics. Regulates the interaction of microtubules tips with the centrosome and cell cortex. (2013 aa) |
| | copb | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). (912 aa) |
| | yelA | Yellow mounds protein A; Plays as essential role in regulating terminal differentiation. (909 aa) |
| | DDB0219915 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1403 aa) |
| | psmD2 | 26S proteasome non-ATPase regulatory subunit 2; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (893 aa) |
| | DDB0192052 | Uncharacterized protein. (991 aa) |
| | DG1098 | Developmental protein. (2043 aa) |
| | GxcY | Uncharacterized protein. (1076 aa) |
| | ipo13A | Importin-13 homolog A; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. (1064 aa) |
| | DDB0219821 | Uncharacterized protein. (1269 aa) |
| | ZizB | Uncharacterized protein; Belongs to the DOCK family. (2147 aa) |
| | xpo6 | Exportin-6; Probably mediates the nuclear export of actin and profilin- actin complexes; Belongs to the exportin family. (1047 aa) |
| | api5 | Apoptosis inhibitor 5 homolog; May be an antiapoptotic factor. (606 aa) |
| | Ctnnbl1 | DUF1716 domain-containing protein. (525 aa) |
| | DDB0184367 | Uncharacterized protein. (812 aa) |
| | PsmE4 | Uncharacterized protein. (1905 aa) |
| | DDB0184284 | Uncharacterized protein. (1825 aa) |
| | xpo7 | Exportin-7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity; Belongs to the exportin family. (1007 aa) |
| | DDB0184177 | Uncharacterized protein. (437 aa) |
| | xpo2 | Exportin-2; Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity); Belongs to the XPO2/CSE1 family. (951 aa) |
| | eif3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (246 aa) |
| | atr1 | Probable serine/threonine-protein kinase atr1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q (By similarity); Belongs to the PI3/PI4-kinase family. ATM subfamily. (3157 aa) |
| | forJ | Formin-J; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (2546 aa) |
| | xpo1 | Exportin-1; Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES). (1057 aa) |
| | DDB_G0291650 | Probable importin-5 homolog; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates (By similarity); Belongs to the importin beta family. Importin beta-3 subfamily. (1067 aa) |
| | DDB0183788 | PKD_channel domain-containing protein. (823 aa) |
| | raptor | Protein raptor homolog. (1509 aa) |
| | scy2 | Probable inactive serine/threonine-protein kinase scy2. (1125 aa) |
| | CLASP | CLIP-associating protein. (899 aa) |
| | Mon2 | Uncharacterized protein. (1874 aa) |
| | mroh1 | Maestro heat-like repeat-containing protein family member 1. (1647 aa) |
| | PikH | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1820 aa) |
| | thoc2 | Uncharacterized protein. (2110 aa) |
| | DDB0189122 | Uncharacterized protein. (339 aa) |
| | DDB0219603 | SEC7 domain-containing protein. (1748 aa) |
| | DDB0188941 | Uncharacterized protein. (237 aa) |
| | DDB0219543 | Uncharacterized protein. (946 aa) |
| | DDB0188671 | Uncharacterized protein. (1036 aa) |
| | DDB_G0289943 | Protein CLEC16A homolog; Regulator of mitophagy. (1550 aa) |
| | DDB0188563 | LisH domain-containing protein. (1169 aa) |
| | copG | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). (898 aa) |
| | DDB0188326 | Uncharacterized protein. (801 aa) |
| | smkA | Suppressor of Mek1; Suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects. Required for proper cytokinesis during vegetative growth, timely exit from the mound stage during development, and myosin II assembly. May be a regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) and may control localization of PP4 to the nucleus. Involved in the regulation of some ppp4c functions, such as developmental progression, chemotaxis, expression of stress response genes and cell movement; Belongs to the SMEK family. (1046 aa) |
| | aarA | Protein aardvark; Required to regulate pattern formation during multi-cellular stages of development and for the formation of adherens junctions. Plays a structural role during the regulation of stalk formation. Involved in cell signaling. Required for spore-cell differentiation. Overexpression increases number and size of cell junctions and reduces spore-cell formation; Belongs to the beta-catenin family. (757 aa) |
| | DDB0188128 | Uncharacterized protein. (1437 aa) |
| | DDB0187989 | PUM-HD domain-containing protein. (679 aa) |
| | TAF6 | TATA-binding protein-associated-factor. (542 aa) |
| | mms19 | MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins (By similarity). (1115 aa) |
| | DDB0187836 | Telomere_reg-2 domain-containing protein. (935 aa) |
| | DDB0187827 | IFRD domain-containing protein. (460 aa) |
| | DDB0187751 | Uncharacterized protein. (2950 aa) |
| | DDB0187732 | Vac14_Fab1_bd domain-containing protein. (1878 aa) |
| | psmD1 | 26S proteasome non-ATPase regulatory subunit 1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (975 aa) |
| | forC | Formin-C; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1158 aa) |
| | DDB0187369 | HECT domain-containing protein. (1898 aa) |
| | eif5 | Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]) (By similarity). (393 aa) |
| | ints4 | Integrator complex subunit 4 homolog; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing; Belongs to the Integrator subunit 4 family. (1233 aa) |
| | Dnajc13 | J domain-containing protein. (2592 aa) |
| | DDB0186863 | Uncharacterized protein. (2005 aa) |
| | DDB0186811 | Uncharacterized protein. (370 aa) |
| | heatr1 | HEAT repeat-containing protein 1 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I; Belongs to the HEATR1/UTP10 family. (2237 aa) |
| | forH | Formin-H; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. Important for cell migration and formation, elongation and maintenance of filopodia. Specifically controls filopodial dynamics by regulating actin turnover at the barbed ends of actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1087 aa) |
| | DDB0186522 | Uncharacterized protein. (523 aa) |
| | tstA | TSET complex member tstA. (1408 aa) |
| | grfA | DH domain-containing protein. (1215 aa) |
| | DDB0186216 | Rap-GAP domain-containing protein. (1640 aa) |
| | DDB0186116 | Fes1 domain-containing protein. (385 aa) |
| | DDB0186073 | MI domain-containing protein. (998 aa) |
| | ints7 | Integrator complex subunit 7 homolog; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing; Belongs to the Integrator subunit 7 family. (1024 aa) |
| | DDB0185982 | Uncharacterized protein. (802 aa) |
| | xpo5 | Exportin-5; Mediates the nuclear export of proteins bearing a double- stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). Belongs to the exportin family. (1135 aa) |
| | Sympk | Uncharacterized protein. (1493 aa) |
| | DDB0185626 | SCD domain-containing protein. (1339 aa) |
| | pppA | Protein phosphatase 2A scaffold subunit; Scaffolding molecule which may coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. (584 aa) |
| | DDB0218516 | Uncharacterized protein. (914 aa) |
| | DDB0218513 | Importin N-terminal domain-containing protein. (981 aa) |
| | ap4b1 | AP-4 complex subunit beta; Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. (838 aa) |
| | eif2b5 | Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. (707 aa) |
| | xpot | Exportin-T; Mediates the nuclear export of aminoacylated tRNAs. Belongs to the exportin family. (1088 aa) |
| | DDB0185354 | Sister chromatid cohesion protein. (2063 aa) |
| | vps15 | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (1966 aa) |
| | PikG | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1671 aa) |
| | DDB0204859 | Uncharacterized protein. (1069 aa) |
| | DDB0204229 | Uncharacterized protein. (1398 aa) |
| | forB | Formin-B; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1126 aa) |
| | tra1 | Probable transcription-associated protein 1; Belongs to the PI3/PI4-kinase family. TRA1 subfamily. (4582 aa) |
| | DDB0204282 | Uncharacterized protein. (611 aa) |
| | tstB | TSET complex member tstB. (877 aa) |
| | DDB0204665 | SIAH-type domain-containing protein. (407 aa) |
| | DDB0204566 | Uncharacterized protein. (1395 aa) |
| | ppr1 | Protein phosphatase 4 regulatory subunit 1. (726 aa) |
| | DDB0205569 | Uncharacterized protein. (1536 aa) |
| | DDB0204153 | Uncharacterized protein. (2167 aa) |
| | lvsC | BEACH domain-containing protein lvsC. (2491 aa) |
| | dnapkcs | DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Is recruited to DNA ends by the Ku70/Ku80 heterodimer and is involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (By similarity). This activity is only apparent when DNA damage is administered in G1 phase of the cell cycle. Required for efficient signaling of DNA double-stranded breaks via phosphorylation of H2AX during G1; Belongs to the PI3/PI4-kinase family. DNAPK subfamily. (4299 aa) |
| | xpo4 | Exportin-4; Mediates the nuclear export of proteins (cargos) with broad substrate specificity; Belongs to the exportin family. (1133 aa) |
| | DDB0218256 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1229 aa) |
| | DDB0204738 | ETS domain-containing protein. (1427 aa) |
| | DDB0218242 | Rap-GAP domain-containing protein. (2935 aa) |
| | DDB0205220 | Uncharacterized protein. (1828 aa) |
| | psrA | Serine/threonine-protein phosphatase 2A regulatory subunit psrA; Involved in developmental cell fate decision. Belongs to the phosphatase 2A regulatory subunit B56 family. (628 aa) |
| | ap4e1 | AP-4 complex subunit epsilon; Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. (1080 aa) |
| | DDB0206444 | Uncharacterized protein. (1589 aa) |
| | DDB0206443 | CLASP_N domain-containing protein. (285 aa) |
| | DDB_G0280205 | Uncharacterized protein DDB_G0280205. (835 aa) |
| | DDB_G0280131 | Probable inactive serine/threonine-protein kinase DDB_G0280131. (1192 aa) |
| | DDB0206317 | Uncharacterized protein. (547 aa) |
| | PufA | RNA binding protein. (785 aa) |
| | DDB0206011 | C2 NT-type domain-containing protein. (855 aa) |
| | DDB0205990 | Importin N-terminal domain-containing protein. (1025 aa) |
| | forA | Formin-A; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1218 aa) |
| | DDB0205845 | PUM-HD domain-containing protein. (782 aa) |
| | ap3d1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway. (1143 aa) |
| | gcn1 | eIF-2-alpha kinase activator GCN1; Acts as a positive activator of the gcn2 protein kinase activity in response to amino acid starvation. Forms a complex with eif2ak4/gcn2 on translating ribosomes; during this process, gcn1 seems to act as a chaperone to facilitate delivery of uncharged tRNAs that enter the A site of ribosomes to the tRNA-binding domain of eif2ak4/gcn2, and hence stimulating eif2ak4/gcn2 kinase activity. Participates in the repression of global protein synthesis and in gene- specific mRNA translation activation, such as the transcriptional activator atf4, by promoting [...] (2667 aa) |
| | ipo13B | Importin-13 homolog B; Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. (1119 aa) |
| | DDB0205723 | Cnd3 domain-containing protein. (1303 aa) |
| | cnrP | Putative countin receptor Cnr17. (1110 aa) |
| | DDB0205647 | CBF domain-containing protein. (1053 aa) |
| | ap1b1 | AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis. (942 aa) |
| | Utp20 | DRIM domain-containing protein. (3103 aa) |
| | DDB0215272 | Uncharacterized protein. (614 aa) |
| | DDB_G0278909 | Probable inactive serine/threonine-protein kinase DDB_G0278909. (1936 aa) |
| | DDB_G0278901 | Probable serine/threonine-protein kinase DDB_G0278901. (1495 aa) |
| | DDB0218111 | Cnd1 domain-containing protein. (1791 aa) |
| | DDB0218106 | Uncharacterized protein. (464 aa) |
| | DDB0205425 | Uncharacterized protein. (588 aa) |
| | vps11 | Vacuolar protein sorting-associated protein 11 homolog; May play a role in vesicle-mediated protein trafficking. Belongs to the VPS11 family. (952 aa) |
| | elmoA | ELMO domain-containing protein A; Functions as a negative regulator of actin polymerization. Modulates actin/myosin II at cortex actinomyosins to prevent excessive F-actin polymerization around the cell periphery, thereby maintaining proper cell shape during phagocytosis and chemotaxis. (977 aa) |
| | DDB0204354 | Importin subunit alpha; Belongs to the importin alpha family. (524 aa) |
| | DDB0218030 | Uncharacterized protein. (768 aa) |
| | DDB0217977 | Uncharacterized protein. (1657 aa) |
| | DDB_G0277537 | Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family. (2460 aa) |
| | DDB0217783 | DUF1741 domain-containing protein. (1003 aa) |
| | DDB0217770 | PUM-HD domain-containing protein. (841 aa) |
| | DDB0220591 | Uncharacterized protein. (316 aa) |
| | pds5 | Sister chromatid cohesion protein PDS5 homolog; May regulate sister chromatid cohesion during mitosis and couple it to DNA replication; Belongs to the PDS5 family. (1450 aa) |
| | DDB0202473 | Uncharacterized protein. (548 aa) |
| | smg1 | Probable serine/threonine-protein kinase smg1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating upf1 (By similarity). (2344 aa) |
| | DDB0217648 | DUF2428 domain-containing protein. (2176 aa) |
| | DDB0202550 | Uso1_p115_head domain-containing protein. (1048 aa) |
| | eif4g | Eukaryotic translation initiation factor 4 gamma; Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. (1377 aa) |
| | DDB0217656 | Uncharacterized protein; Belongs to the peptidase C19 family. (2991 aa) |
| | DDB0217636 | Uncharacterized protein. (2868 aa) |
| | DDB0220000 | Cell differentiation family, Rcd1-like protein. (941 aa) |
| | ZizC | Uncharacterized protein; Belongs to the DOCK family. (2621 aa) |
| | DDB0217579 | Uncharacterized protein. (806 aa) |
| | rnf160 | E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to cdcD/CDC48 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family. (1864 aa) |
| | dohh-1 | Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF- 5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. (315 aa) |
| | ap3b-1 | AP-3 complex subunit beta; Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway. (1108 aa) |
| | DDB0202999 | Uncharacterized protein. (87 aa) |
| | DDB0168059 | SEC7 domain-containing protein. (2048 aa) |
| | DDB_G0273149 | Probable importin subunit alpha-A; Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Binds specifically and directly to substrates containing either a simple or bipartite NLS motif (By similarity). (550 aa) |
| | DDB_G0272975 | BTB domain-containing protein. (692 aa) |
| | numA | Nucleomorphin. (756 aa) |
| | iplA | Inositol 1,4,5-trisphosphate receptor-like protein A; May be a receptor for inositol 1,4,5 trisphosphate which governs calcium fluxes from the endoplasmic reticulum stores into the cytosol. May be involved in autophagic cell death. (3177 aa) |
| | Utp5 | WD_REPEATS_REGION domain-containing protein. (569 aa) |
| | sepA | Serine/threonine-protein kinase sepA; Serine/threonine-protein kinase involved in the spatial and temporal control system organizing cortical activities in mitotic and postmitotic cells. (1167 aa) |
| | vatH | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). (445 aa) |
| | ap1g1 | AP-1 complex subunit gamma; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis. (895 aa) |
| | Wdr7 | Uncharacterized protein. (1342 aa) |
| | ap2a1-1 | AP-2 complex subunit alpha-2; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (989 aa) |
| | cand1 | Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (By similarity); Belongs to the CAND family. (1238 aa) |
| | lvsB | BEACH domain-containing protein lvsB; Involved in negative regulation of lysosome biogenesis, by limiting the heterotypic fusion of early endosomes and postlysosomal compartments. (4118 aa) |
| | Sf3b1 | TOG domain-containing protein. (1051 aa) |
| | ZizA | Uncharacterized protein; Belongs to the DOCK family. (2284 aa) |
| | DDB0167485 | Cnd3 domain-containing protein. (1326 aa) |
| | DDB0167042 | Uncharacterized protein. (716 aa) |
| | tor | Serine/threonine-protein kinase tor; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein [...] (2380 aa) |
| | DDB0168274 | Uncharacterized protein. (1041 aa) |
| | DDB_G0272318 | Importin subunit alpha-B; Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Binds specifically and directly to substrates containing either a simple or bipartite NLS motif (By similarity). (516 aa) |
| | htt | HD protein homolog; May play a role in microtubule-mediated transport or vesicle function; Belongs to the huntingtin family. (3095 aa) |
| | DDB0217054 | Uncharacterized protein. (559 aa) |
| | DDB_G0276861 | Protein HGH1 homolog; Belongs to the HGH1 family. (355 aa) |
| | DDB0168794 | Uncharacterized protein. (630 aa) |
| | forE | Formin-E; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1561 aa) |
| | forF | Formin-F; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1220 aa) |
| | forD | Formin-D; Formins play an important role in the nucleation of actin and the formation of linear actin filaments; Belongs to the formin homology family. Diaphanous subfamily. (1214 aa) |
| | scy1 | Probable inactive serine/threonine-protein kinase scy1. (813 aa) |
| | DDB0189451 | Uncharacterized protein. (661 aa) |
| | tbcd | Tubulin-specific chaperone D; Tubulin-folding protein; involved in the first step of the tubulin folding pathway; Belongs to the TBCD family. (1480 aa) |
| | DDB0189538 | Uncharacterized protein. (1426 aa) |
| | DDB0189551 | MI domain-containing protein. (925 aa) |
| | PikF | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1382 aa) |
| | tsuA | Probable serine/threonine-protein kinase tsuA; Plays a role in chemotaxis and seems to be involved in polarization. (2247 aa) |
| | DDB0202213 | FYVE-type domain-containing protein. (583 aa) |
| | lvsG | Probable inactive serine/threonine-protein kinase lvsG. (2179 aa) |
| | gefV | Ras guanine nucleotide exchange factor V; Promotes the exchange of Ras-bound GDP by GTP. (1982 aa) |
| | DDB_G0268924 | AAA domain-containing protein. (1772 aa) |
| | DDB_G0268876 | Probable serine/threonine-protein kinase DDB_G0268876; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. (1385 aa) |
| | atxn10 | Ataxin-10 homolog; Belongs to the ATXN10 family. (609 aa) |
| | AF037042_3 | Ipi1_N domain-containing protein. (959 aa) |
| | DDB0190400 | Uncharacterized protein. (839 aa) |
| | sdad1 | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (756 aa) |
| | armc8 | Armadillo repeat-containing protein. (702 aa) |
| | DDB0216421 | Cell differentiation family, Rcd1-like protein. (360 aa) |
| | ncbp1 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp1 does not bind directly capped RNAs (m7GpppG- capped RNA) but is required to stabilize the movement of the N-terminal loop of ncbp2 and lock the CBC into a high affinity cap-binding state with the cap [...] (772 aa) |
| | DDB_G0269860 | Probable importin-7 homolog; May function in nuclear protein import; Belongs to the importin beta family. (1065 aa) |
| | tnpo | Transportin; Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Mediates docking of the substrate-importin complex to distinct nucleoporins (By similarity). (931 aa) |
| | DDB0190705 | Uncharacterized protein. (299 aa) |
| | DDB0216762 | Uncharacterized protein. (220 aa) |
| | Ipo4 | Importin N-terminal domain-containing protein. (1103 aa) |
