STRINGSTRING
myoI myoI frmB frmB talA talA frmA frmA frmC frmC talB talB myoG myoG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
myoIMyosin-I heavy chain; Myosins are actin-based motor molecules with ATPase activity. Involved in the early steps of phagocytosis and adhesion. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2357 aa)
frmBFERM domain-containing protein B. (478 aa)
talATalin-A; Actin-binding protein that may be involved in the control of cell motility and chemotaxis. (1279 aa)
frmAFERM domain-containing protein A; Key regulator of adhesion dynamics, it acts as an anti- adhesive. Plays a critical role in the regulation of cell-cell adhesion, multi-cellular development and, in particular, the formation of the organising center known as the tip. Required for turnover of paxillin-adhesion sites during cell migration. Plays a major role in normal cell shape, cell-substrate adhesion and actin cytoskeleton organization. (1154 aa)
frmCFERM domain-containing protein C. (1489 aa)
talBTalin-B; Actin-binding protein required for multicellular morphogenesis. Substrate of pkgB and/or pkbA. (2614 aa)
myoGMyosin-G heavy chain; Myosins are actin-based motor molecules with ATPase activity. (3446 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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