68 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDB0167842	C2 domain-containing protein. (320 aa)
	DDB0206452	Uncharacterized protein. (2176 aa)
	DG1113	Developmental protein. (1157 aa)
	dwwA	WW domain-containing protein A; Involved in regulation of actin cytoskeleton organization and cytokinesis. (568 aa)
	DDB0205121	Uncharacterized protein. (464 aa)
	PSD2	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (563 aa)
	PikG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1671 aa)
	DDB0185556	C2 domain-containing protein. (138 aa)
	DDB0186020	C2 domain-containing protein. (623 aa)
	DocD	Uncharacterized protein; Belongs to the DOCK family. (1924 aa)
	cpnC	Copine-C. (539 aa)
	DDB0186671	PX domain-containing protein. (329 aa)
	DDB_G0285967	LIM-type zinc finger-containing protein. (998 aa)
	DDB0186819	J domain-containing protein. (814 aa)
	DDB_G0288795	Probable serine/threonine-protein kinase DDB_G0288795. (641 aa)
	DDB0219504	Uncharacterized protein. (904 aa)
	ascc3	Activating signal cointegrator 1 complex subunit 3. (2195 aa)
	cpnE	Copine-E. (579 aa)
	DDB0188984	C2 domain-containing protein. (496 aa)
	DDB_G0290753	C2 domain-containing protein DDB_G0290753. (195 aa)
	DDB0189065	C2 domain-containing protein. (181 aa)
	DDB0189193	Uncharacterized protein. (1335 aa)
	ZizC	Uncharacterized protein; Belongs to the DOCK family. (2621 aa)
	DDB_G0272092	Probable serine/threonine-protein kinase DDB_G0272092; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. (986 aa)
	DocB	Uncharacterized protein; Belongs to the DOCK family. (2176 aa)
	DDB0190778	Uncharacterized protein. (1495 aa)
	adcC	Arrestin domain-containing protein C; Belongs to the arrestin family. (654 aa)
	ascc3l	Activating signal cointegrator 1 complex subunit 3-like; Belongs to the helicase family. (2237 aa)
	DDB0190600	C2 domain-containing protein. (261 aa)
	DDB0190455	Uncharacterized protein. (568 aa)
	DDB0190346	C2 domain-containing protein. (1546 aa)
	DDB0190183	C2 domain-containing protein. (319 aa)
	ZizD	Uncharacterized protein; Belongs to the DOCK family. (2162 aa)
	DDB0189950	Uncharacterized protein. (1414 aa)
	PikF	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1382 aa)
	DDB0202179	Uncharacterized protein. (961 aa)
	cpnD	Copine-D. (530 aa)
	DDB_G0272734	C2 domain-containing protein. (163 aa)
	cpnA	Copine-A; Required for cytokinesis, contractile vacuole function and development; Belongs to the copine family. (600 aa)
	DDB0216964	C2 domain-containing protein; Belongs to the complex I LYR family. (637 aa)
	ZizA	Uncharacterized protein; Belongs to the DOCK family. (2284 aa)
	egeA	C2 domain-containing protein. (254 aa)
	cpnB-1	Copine-B. (530 aa)
	adcB	Arrestin domain-containing protein B; Belongs to the arrestin family. (617 aa)
	DDB_G0272752	C2 domain-containing protein. (178 aa)
	cplA	Putative processed calpain-like cysteine protease A; Has a weak caseinolytic activity. Belongs to the peptidase C2 family. (649 aa)
	pteN	3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] (533 aa)
	DDB0217625	Uncharacterized protein. (2107 aa)
	DDB0217695	Uncharacterized protein. (527 aa)
	cnrO	C2 domain-containing protein. (132 aa)
	ngap	Probable Ras GTPase-activating-like protein ngap; May function as a Ras GTPase-activating protein. (877 aa)
	forA	Formin-A; Formins play an important role in the nucleation of actin and the formation of linear actin filaments. (1218 aa)
	DDB0205870	C2 domain-containing protein. (170 aa)
	DDB0205932	Uncharacterized protein. (1010 aa)
	PikH	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1820 aa)
	gacEE	Rho GTPase-activating protein gacEE; Rho GTPase-activating protein involved in the signal transduction pathway. (570 aa)
	docA	Uncharacterized protein; Belongs to the DOCK family. (2221 aa)
	DDB0191697	Uncharacterized protein. (453 aa)
	ZizB	Uncharacterized protein; Belongs to the DOCK family. (2147 aa)
	DDB_G0293992	C2 domain-containing protein. (158 aa)
	cpnF	Copine-F. (550 aa)
	plc	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (801 aa)
	pikE	Phosphatidylinositol 3-kinase VPS34-like. (816 aa)
	pikC	Phosphatidylinositol 3-kinase 3. (1697 aa)
	pikB	Phosphatidylinositol 3-kinase 2. (1857 aa)
	pikA	Phosphatidylinositol 3-kinase 1. (1571 aa)
	R2005	C2 domain-containing protein. (425 aa)
	DDB_G0294603	C2 domain-containing protein. (174 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0186819	ascc3	Q54M91	Q54G57	J domain-containing protein.	Activating signal cointegrator 1 complex subunit 3.	0.701
DDB0186819	ascc3l	Q54M91	Q55CI8	J domain-containing protein.	Activating signal cointegrator 1 complex subunit 3-like; Belongs to the helicase family.	0.701
DDB0189950	DDB0190455	Q55F06	Q55DG0	Uncharacterized protein.	Uncharacterized protein.	0.997
DDB0189950	DDB0190600	Q55F06	Q55D03	Uncharacterized protein.	C2 domain-containing protein.	0.406
DDB0190455	DDB0189950	Q55DG0	Q55F06	Uncharacterized protein.	Uncharacterized protein.	0.997
DDB0190455	DDB_G0290753	Q55DG0	Q54FM6	Uncharacterized protein.	C2 domain-containing protein DDB_G0290753.	0.702
DDB0190600	DDB0189950	Q55D03	Q55F06	C2 domain-containing protein.	Uncharacterized protein.	0.406
DDB0190600	DDB_G0294603	Q55D03	B0G179	C2 domain-containing protein.	C2 domain-containing protein.	0.487
DDB0191697	DDB_G0285967	Q54CH3	Q54MG8	Uncharacterized protein.	LIM-type zinc finger-containing protein.	0.913
DDB0191697	DDB_G0288795	Q54CH3	Q54IF2	Uncharacterized protein.	Probable serine/threonine-protein kinase DDB_G0288795.	0.439
DDB0191697	PikF	Q54CH3	Q55FX5	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.900
DDB0191697	PikG	Q54CH3	Q54S78	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.900
DDB0191697	PikH	Q54CH3	Q54F55	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.900
DDB0191697	pikA	Q54CH3	P54673	Uncharacterized protein.	Phosphatidylinositol 3-kinase 1.	0.923
DDB0191697	pikB	Q54CH3	P54674	Uncharacterized protein.	Phosphatidylinositol 3-kinase 2.	0.923
DDB0191697	pikC	Q54CH3	P54675	Uncharacterized protein.	Phosphatidylinositol 3-kinase 3.	0.900
DDB0191697	pikE	Q54CH3	P54676	Uncharacterized protein.	Phosphatidylinositol 3-kinase VPS34-like.	0.921
DDB0191697	plc	Q54CH3	Q02158	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.908
DDB0191697	pteN	Q54CH3	Q8T9S7	Uncharacterized protein.	3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...]	0.916
DDB0205121	ngap	Q54T13	Q54Y08	Uncharacterized protein.	Probable Ras GTPase-activating-like protein ngap; May function as a Ras GTPase-activating protein.	0.416