20 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	racA	Rho-related protein racA. (598 aa)
	racB	Rho-related protein racB; Belongs to the small GTPase superfamily. Rho family. (195 aa)
	racC	Rho-related protein racC; Belongs to the small GTPase superfamily. Rho family. (192 aa)
	racD	Rho-related protein racD; Belongs to the small GTPase superfamily. Rho family. (254 aa)
	racQ	Rho GTPase. (185 aa)
	racE	Rho-related protein racE; Specifically required for cytokinesis; Belongs to the small GTPase superfamily. Rho family. (223 aa)
	racM	Rho-related protein racM. (189 aa)
	RacP	Rho GTPase. (376 aa)
	racN	Rho-related protein racN. (219 aa)
	racO	Rho-related protein racO. (276 aa)
	racL	Rho-related protein racL. (196 aa)
	racF2	Rho-related protein racF2. (193 aa)
	racG	Rho-related protein racG. (201 aa)
	racH	Rho-related protein racH. (200 aa)
	racJ	Rho-related protein racJ. (205 aa)
	racI	Rho-related protein racI. (205 aa)
	racF1	Rho-related protein racF1; Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes. (193 aa)
	rac1A	Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family. (194 aa)
	rac1B	Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles. (194 aa)
	rac1C	Rho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles. (193 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RacP	rac1A	Q54N82	P34144	Rho GTPase.	Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.	0.524
RacP	rac1B	Q54N82	P34145	Rho GTPase.	Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles.	0.525
RacP	rac1C	Q54N82	P34146	Rho GTPase.	Rho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles.	0.524
RacP	racB	Q54N82	P34148	Rho GTPase.	Rho-related protein racB; Belongs to the small GTPase superfamily. Rho family.	0.525
RacP	racC	Q54N82	P34149	Rho GTPase.	Rho-related protein racC; Belongs to the small GTPase superfamily. Rho family.	0.531
RacP	racE	Q54N82	Q23862	Rho GTPase.	Rho-related protein racE; Specifically required for cytokinesis; Belongs to the small GTPase superfamily. Rho family.	0.545
RacP	racF1	Q54N82	O96390	Rho GTPase.	Rho-related protein racF1; Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes.	0.531
RacP	racF2	Q54N82	Q9GPS3	Rho GTPase.	Rho-related protein racF2.	0.531
RacP	racG	Q54N82	Q9GPS0	Rho GTPase.	Rho-related protein racG.	0.535
RacP	racH	Q54N82	Q9GPR7	Rho GTPase.	Rho-related protein racH.	0.547
RacP	racI	Q54N82	Q9GPR2	Rho GTPase.	Rho-related protein racI.	0.554
RacP	racL	Q54N82	Q9GPQ8	Rho GTPase.	Rho-related protein racL.	0.544
RacP	racM	Q54N82	Q54HZ7	Rho GTPase.	Rho-related protein racM.	0.540
RacP	racN	Q54N82	Q54YY4	Rho GTPase.	Rho-related protein racN.	0.554
RacP	racO	Q54N82	Q54Z85	Rho GTPase.	Rho-related protein racO.	0.553
RacP	racQ	Q54N82	Q1ZXJ6	Rho GTPase.	Rho GTPase.	0.562
rac1A	RacP	P34144	Q54N82	Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.	Rho GTPase.	0.524
rac1A	rac1B	P34144	P34145	Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.	Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles.	0.507
rac1A	rac1C	P34144	P34146	Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.	Rho-related protein rac1C; Overexpression promotes the formation of filopodia and membrane ruffles.	0.507
rac1A	racB	P34144	P34148	Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.	Rho-related protein racB; Belongs to the small GTPase superfamily. Rho family.	0.513