11 items (Dictyostelium discoideum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ndkC-1	Nucleoside diphosphate kinase, cytosolic; Major role in the synthesis of nucleoside triphosphates other than ATP; Belongs to the NDK family. (155 aa)
	ndkM	Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (220 aa)
	tubA	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (457 aa)
	dymB	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (920 aa)
	fszB	Mitochondrial division protein fszB; Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family. (366 aa)
	dymA	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway. (853 aa)
	dlpA	Dynamin-like protein A; Involved in cytokinesis. May hydrolyze GTP. (880 aa)
	dlpC	Dynamin-like protein C; Involved in cytokinesis. May hydrolyze GTP. (904 aa)
	fszA	Mitochondrial division protein fszA; Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family. (517 aa)
	dlpB	Dynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP. (808 aa)
	DDB_G0292928	Probable nucleoside diphosphate kinase DDB_G0292928. (160 aa)

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB_G0292928	dymB	Q54CG9	Q9U1M9	Probable nucleoside diphosphate kinase DDB_G0292928.	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.448
DDB_G0292928	ndkC-1	Q54CG9	P22887	Probable nucleoside diphosphate kinase DDB_G0292928.	Nucleoside diphosphate kinase, cytosolic; Major role in the synthesis of nucleoside triphosphates other than ATP; Belongs to the NDK family.	0.921
DDB_G0292928	ndkM	Q54CG9	P34093	Probable nucleoside diphosphate kinase DDB_G0292928.	Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.968
DDB_G0292928	tubA	Q54CG9	P32255	Probable nucleoside diphosphate kinase DDB_G0292928.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family.	0.436
dlpA	dlpC	Q55F94	Q55AX0	Dynamin-like protein A; Involved in cytokinesis. May hydrolyze GTP.	Dynamin-like protein C; Involved in cytokinesis. May hydrolyze GTP.	0.443
dlpB	dymA	Q54MH8	Q94464	Dynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP.	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.	0.791
dlpB	dymB	Q54MH8	Q9U1M9	Dynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP.	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.787
dlpC	dlpA	Q55AX0	Q55F94	Dynamin-like protein C; Involved in cytokinesis. May hydrolyze GTP.	Dynamin-like protein A; Involved in cytokinesis. May hydrolyze GTP.	0.443
dymA	dlpB	Q94464	Q54MH8	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.	Dynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP.	0.791
dymA	fszA	Q94464	Q54Z54	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.	Mitochondrial division protein fszA; Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	0.719
dymA	fszB	Q94464	Q9GPZ7	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.	Mitochondrial division protein fszB; Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	0.725
dymB	DDB_G0292928	Q9U1M9	Q54CG9	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Probable nucleoside diphosphate kinase DDB_G0292928.	0.448
dymB	dlpB	Q9U1M9	Q54MH8	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin-like protein B; Involved in cytokinesis. May hydrolyze GTP.	0.787
dymB	fszA	Q9U1M9	Q54Z54	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitochondrial division protein fszA; Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	0.740
dymB	fszB	Q9U1M9	Q9GPZ7	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mitochondrial division protein fszB; Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	0.793
dymB	ndkC-1	Q9U1M9	P22887	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Nucleoside diphosphate kinase, cytosolic; Major role in the synthesis of nucleoside triphosphates other than ATP; Belongs to the NDK family.	0.412
dymB	ndkM	Q9U1M9	P34093	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Nucleoside diphosphate kinase, mitochondrial; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.414
fszA	dymA	Q54Z54	Q94464	Mitochondrial division protein fszA; Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.	0.719
fszA	dymB	Q54Z54	Q9U1M9	Mitochondrial division protein fszA; Probably involved in mitochondrion division process. When overexpressed, induces mitochondrial tubule formation. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	Dynamin-B; Enzyme hydrolyzing GTP; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.740
fszB	dymA	Q9GPZ7	Q94464	Mitochondrial division protein fszB; Probably involved in mitochondrion division process. Binds to and hydrolyzes GTP (By similarity); Belongs to the FtsZ family.	Dynamin-A; Function in membrane trafficking processes along the endo- lysosomal pathway.	0.725