node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dd5P3 | pikA | Q54D97 | P54673 | Inositol 5-phosphatase. | Phosphatidylinositol 3-kinase 1. | 0.902 |
Dd5P3 | pteN | Q54D97 | Q8T9S7 | Inositol 5-phosphatase. | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | 0.922 |
arfA | rab11A | O00909 | P36412 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. | 0.608 |
arfA | rabS | O00909 | Q54SD0 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | Ras-related protein RabS. | 0.699 |
pikA | Dd5P3 | P54673 | Q54D97 | Phosphatidylinositol 3-kinase 1. | Inositol 5-phosphatase. | 0.902 |
pikA | pteN | P54673 | Q8T9S7 | Phosphatidylinositol 3-kinase 1. | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | 0.950 |
pikA | rab11A | P54673 | P36412 | Phosphatidylinositol 3-kinase 1. | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. | 0.471 |
pikA | vps15 | P54673 | Q54S77 | Phosphatidylinositol 3-kinase 1. | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.690 |
pteN | Dd5P3 | Q8T9S7 | Q54D97 | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | Inositol 5-phosphatase. | 0.922 |
pteN | pikA | Q8T9S7 | P54673 | 3-phosphatidylinositol 3-phosphatase; Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5- trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity). Negative regulator of PI3K chemotaxis pathways. Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotax [...] | Phosphatidylinositol 3-kinase 1. | 0.950 |
rab11A | arfA | P36412 | O00909 | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | 0.608 |
rab11A | pikA | P36412 | P54673 | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. | Phosphatidylinositol 3-kinase 1. | 0.471 |
rab11A | rabS | P36412 | Q54SD0 | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. | Ras-related protein RabS. | 0.519 |
rabS | arfA | Q54SD0 | O00909 | Ras-related protein RabS. | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. | 0.699 |
rabS | rab11A | Q54SD0 | P36412 | Ras-related protein RabS. | Ras-related protein Rab-11A; Required for normal contractile vacuole structure and function. Cells expressing a dominant negative rab11A exhibit a more extensive contractile vacuole network and enlarged contractile vacuole bladders. These cells exhibit a functional defect in osmotic regulation where cells immersed in water become rounded and detach from the surface, and contain swollen contractile vacuoles. Belongs to the small GTPase superfamily. Rab family. | 0.519 |
vps15 | pikA | Q54S77 | P54673 | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Phosphatidylinositol 3-kinase 1. | 0.690 |