STRINGSTRING
fam49 fam49 gefS gefS pirA pirA brk1 brk1 rac1A rac1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fam49Protein FAM49 homolog; Belongs to the FAM49 family. (315 aa)
gefSRas guanine nucleotide exchange factor S; Promotes the exchange of Ras-bound GDP by GTP. (1043 aa)
pirAProtein pirA; Involved in regulation of actin and microtubule organization. (1336 aa)
brk1Protein BRICK1; Involved in regulation of actin and microtubule organization. Belongs to the BRK1 family. (68 aa)
rac1ARho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family. (194 aa)
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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