16 items (Histoplasma capsulatum G186AR) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	HCBG_00120	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (488 aa)
	HCBG_00414	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1160 aa)
	HCBG_02195	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (428 aa)
	HCBG_02341	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (406 aa)
	HCBG_03424	Dehydrodolichyl diphosphate synthetase. (412 aa)
	HCBG_03737	Uncharacterized protein. (387 aa)
	HCBG_04208	DUF2236 domain-containing protein. (361 aa)
	HCBG_04904	Uncharacterized protein. (523 aa)
	HCBG_04940	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (542 aa)
	HCBG_05097	Isopentenyl-diphosphate delta-isomerase. (272 aa)
	HCBG_05534	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (403 aa)
	HCBG_06331	Uncharacterized protein. (144 aa)
	HCBG_06384	Farnesyl-pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (347 aa)
	HCBG_06726	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (475 aa)
	HCBG_07254	Uncharacterized protein. (493 aa)
	HCBG_07716	Decaprenyl-diphosphate synthase subunit 1. (521 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCBG_00120	HCBG_00414	C0NAH4	C0NBB8	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.973
HCBG_00120	HCBG_02195	C0NAH4	C0NID8	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.544
HCBG_00120	HCBG_02341	C0NAH4	C0NIT4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.991
HCBG_00120	HCBG_04904	C0NAH4	C0NP24	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Uncharacterized protein.	0.471
HCBG_00120	HCBG_04940	C0NAH4	C0NP60	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.960
HCBG_00120	HCBG_05097	C0NAH4	C0NPL7	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Isopentenyl-diphosphate delta-isomerase.	0.769
HCBG_00120	HCBG_05534	C0NAH4	C0NRA4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.592
HCBG_00120	HCBG_06384	C0NAH4	C0NTA4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Farnesyl-pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.612
HCBG_00120	HCBG_06726	C0NAH4	C0NUW2	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.912
HCBG_00120	HCBG_07254	C0NAH4	C0NVS4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Uncharacterized protein.	0.565
HCBG_00414	HCBG_00120	C0NBB8	C0NAH4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.973
HCBG_00414	HCBG_02195	C0NBB8	C0NID8	3-hydroxy-3-methylglutaryl coenzyme A reductase.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.575
HCBG_00414	HCBG_02341	C0NBB8	C0NIT4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.891
HCBG_00414	HCBG_04904	C0NBB8	C0NP24	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein.	0.645
HCBG_00414	HCBG_04940	C0NBB8	C0NP60	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.724
HCBG_00414	HCBG_05097	C0NBB8	C0NPL7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Isopentenyl-diphosphate delta-isomerase.	0.758
HCBG_00414	HCBG_05534	C0NBB8	C0NRA4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.689
HCBG_00414	HCBG_06384	C0NBB8	C0NTA4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Farnesyl-pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.716
HCBG_00414	HCBG_06726	C0NBB8	C0NUW2	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.997
HCBG_00414	HCBG_07716	C0NBB8	C0NXS2	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Decaprenyl-diphosphate synthase subunit 1.	0.653