65 items (Histoplasma capsulatum G186AR) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCBG_00083	Uncharacterized protein. (487 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (490 aa)
	HCBG_00187	Ribosomal large subunit. (261 aa)
	HCBG_00614	Uncharacterized protein. (320 aa)
	HCBG_00616	Periodic tryptophan protein. (559 aa)
	HCBG_00771	Multiple RNA-binding domain-containing protein. (801 aa)
	HCBG_01043	Uncharacterized protein. (402 aa)
	HCBG_01071	ATP-dependent RNA helicase DBP9. (624 aa)
	HCBG_01098	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4866 aa)
	HCBG_01129	Ribosomal RNA-processing protein. (1334 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
	HCBG_02120	RNA processing factor. (433 aa)
	HCBG_01263	Nucleolar complex protein. (776 aa)
	HCBG_01501	ATP-dependent RNA helicase DRS1. (829 aa)
	HCBG_01507	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (753 aa)
	HCBG_01544	Ribosome assembly protein RRB1. (495 aa)
	HCBG_01589	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (243 aa)
	HCBG_01686	Uncharacterized protein. (363 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (779 aa)
	HCBG_01793	Nucleolar protein. (617 aa)
	HCBG_01839	Ribosome biogenesis protein RPF2. (338 aa)
	HCBG_02435	Ribosome biogenesis protein Rrp14-C. (553 aa)
	HCBG_02684	C2H2-type domain-containing protein. (115 aa)
	HCBG_02828	Protein MAK16; Belongs to the MAK16 family. (329 aa)
	HCBG_03012	ATP-dependent RNA helicase MAK5; Belongs to the DEAD box helicase family. (771 aa)
	HCBG_02238	RNA recognition domain-containing protein-containing protein. (740 aa)
	HCBG_02250	Ribosomal biogenesis protein Gar2. (530 aa)
	HCBG_02327	Dual specificity phosphatase. (363 aa)
	HCBG_03216	GTP-binding protein. (547 aa)
	HCBG_03226	Puf family RNA-binding protein. (688 aa)
	HCBG_03575	CCAAT-box-binding transcription factor. (1115 aa)
	HCBG_03609	Uncharacterized protein. (350 aa)
	HCBG_03724	rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (120 aa)
	HCBG_03794	RNA helicase. (638 aa)
	HCBG_03850	ATP-dependent RNA helicase MSS116; Belongs to the DEAD box helicase family. (680 aa)
	HCBG_04416	Uncharacterized protein. (243 aa)
	HCBG_04012	60S ribosomal protein L24B. (191 aa)
	HCBG_04209	RNA helicase. (631 aa)
	HCBG_04241	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (565 aa)
	HCBG_04280	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (666 aa)
	HCBG_04896	ATP-dependent RNA helicase DBP7; Belongs to the DEAD box helicase family. (786 aa)
	HCBG_04968	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (441 aa)
	HCBG_05108	ATP-dependent RNA helicase DBP10. (940 aa)
	HCBG_05685	Uncharacterized protein. (696 aa)
	HCBG_05729	WD domain-containing protein. (515 aa)
	HCBG_05291	ATP-dependent RNA helicase DBP3; Belongs to the DEAD box helicase family. (487 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (788 aa)
	HCBG_05458	Large subunit GTPase. (664 aa)
	HCBG_06022	Zinc finger protein. (491 aa)
	HCBG_06051	Uncharacterized protein. (1005 aa)
	HCBG_06546	DUF1665 domain-containing protein. (302 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (697 aa)
	HCBG_06802	Brix domain-containing protein c. (438 aa)
	HCBG_07380	Uncharacterized protein. (1288 aa)
	HCBG_07415	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (194 aa)
	HCBG_07416	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (685 aa)
	HCBG_07444	Curved DNA-binding protein. (414 aa)
	HCBG_07455	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (527 aa)
	HCBG_07617	Uncharacterized protein. (257 aa)
	HCBG_07629	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (230 aa)
	HCBG_08576	Uncharacterized protein. (227 aa)
	HCBG_08697	60S ribosomal subunit assembly/export protein LOC1. (194 aa)
	HCBG_08788	Ribosome biogenesis protein BRX1. (383 aa)
	HCBG_08803	F-box domain-containing protein. (380 aa)
	HCBG_09222	Nucleolar protein NOP2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (704 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	HCBG_00083	C0NQT5	C0NAD7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.781
ERB1	HCBG_00187	C0NQT5	C0NAP1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal large subunit.	0.989
ERB1	HCBG_00614	C0NQT5	C0NBW8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.504
ERB1	HCBG_00616	C0NQT5	C0NBX0	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Periodic tryptophan protein.	0.897
ERB1	HCBG_00771	C0NQT5	C0NCC5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Multiple RNA-binding domain-containing protein.	0.905
ERB1	HCBG_01043	C0NQT5	C0ND47	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.994
ERB1	HCBG_01071	C0NQT5	C0ND75	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP-dependent RNA helicase DBP9.	0.960
ERB1	HCBG_01098	C0NQT5	C0NDA2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	0.664
ERB1	HCBG_01129	C0NQT5	C0NDD3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal RNA-processing protein.	0.889
ERB1	HCBG_01263	C0NQT5	C0NEE7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar complex protein.	0.996
ERB1	HCBG_01501	C0NQT5	C0NF35	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP-dependent RNA helicase DRS1.	0.969
ERB1	HCBG_01507	C0NQT5	C0NF41	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.828
ERB1	HCBG_01544	C0NQT5	C0NF78	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly protein RRB1.	0.918
ERB1	HCBG_01589	C0NQT5	C0NFC3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.996
ERB1	HCBG_01686	C0NQT5	C0NFM0	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.997
ERB1	HCBG_01793	C0NQT5	C0NFX7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar protein.	0.928
ERB1	HCBG_01839	C0NQT5	C0NG23	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein RPF2.	0.992
ERB1	HCBG_02120	C0NQT5	C0NE27	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA processing factor.	0.981
ERB1	HCBG_02238	C0NQT5	C0NII1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA recognition domain-containing protein-containing protein.	0.942
ERB1	HCBG_02250	C0NQT5	C0NIJ3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal biogenesis protein Gar2.	0.984