STRINGSTRING
HCBG_06607 HCBG_06607 HCBG_01922 HCBG_01922 HCBG_01895 HCBG_01895 HCBG_01861 HCBG_01861 HCBG_07711 HCBG_07711 HCBG_01206 HCBG_01206 HCBG_00453 HCBG_00453 HCBG_00799 HCBG_00799 HCBG_00824 HCBG_00824 HCBG_00835 HCBG_00835 HCBG_00848 HCBG_00848 HCBG_00933 HCBG_00933 HCBG_00969 HCBG_00969 HCBG_01126 HCBG_01126 HCBG_01226 HCBG_01226 HCBG_01267 HCBG_01267 HCBG_01288 HCBG_01288 HCBG_01373 HCBG_01373 HCBG_01443 HCBG_01443 HCBG_08111 HCBG_08111 MED4 MED4 HCBG_07442 HCBG_07442 HCBG_07322 HCBG_07322 HCBG_07247 HCBG_07247 HCBG_06709 HCBG_06709 MED10 MED10 HCBG_06636 HCBG_06636 HCBG_06531 HCBG_06531 HCBG_06528 HCBG_06528 HCBG_06161 HCBG_06161 HCBG_06142 HCBG_06142 HCBG_06141 HCBG_06141 HCBG_05964 HCBG_05964 HCBG_05940 HCBG_05940 HCBG_05635 HCBG_05635 HCBG_05466 HCBG_05466 HCBG_05649 HCBG_05649 HCBG_05268 HCBG_05268 HCBG_05185 HCBG_05185 HCBG_04185 HCBG_04185 MED8 MED8 HCBG_04531 HCBG_04531 HCBG_04377 HCBG_04377 HCBG_04329 HCBG_04329 HCBG_03866 HCBG_03866 HCBG_03463 HCBG_03463 HCBG_03444 HCBG_03444 HCBG_03421 HCBG_03421 HCBG_03306 HCBG_03306 HCBG_03191 HCBG_03191 HCBG_02373 HCBG_02373 MED5 MED5 HCBG_02225 HCBG_02225 HCBG_02203 HCBG_02203 HCBG_03050 HCBG_03050 HCBG_02720 HCBG_02720 HCBG_02531 HCBG_02531 MED18 MED18 HCBG_09198 HCBG_09198 HCBG_09145 HCBG_09145 HCBG_08704 HCBG_08704 MED17 MED17 HCBG_08392 HCBG_08392 MED20 MED20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCBG_06607Clock-controlled protein 8. (503 aa)
HCBG_01922Transcriptional repressor Sin3p. (1633 aa)
HCBG_01895FAS1 domain-containing protein. (234 aa)
HCBG_01861Uncharacterized protein. (589 aa)
HCBG_07711COP9 signalosome complex subunit. (472 aa)
HCBG_01206DNA polymerase epsilon subunit Dpb3. (250 aa)
HCBG_00453SP-RING-type domain-containing protein. (1115 aa)
HCBG_00799Ada histone acetyltransferase complex component. (681 aa)
HCBG_00824Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1066 aa)
HCBG_00835Uncharacterized protein. (420 aa)
HCBG_00848JmjC domain-containing protein. (1502 aa)
HCBG_00933NUP214 domain-containing protein. (1472 aa)
HCBG_00969Uncharacterized protein. (742 aa)
HCBG_01126Transcriptional repressor. (876 aa)
HCBG_01226Uncharacterized protein. (268 aa)
HCBG_01267SET domain-containing protein. (487 aa)
HCBG_01288Uncharacterized protein. (993 aa)
HCBG_01373DUF1014 domain-containing protein. (238 aa)
HCBG_01443Transcription initiation factor TFIID subunit 9. (321 aa)
HCBG_08111Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (530 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (356 aa)
HCBG_07442Transcription factor Snf5p. (870 aa)
HCBG_07322RPEL repeat protein. (139 aa)
HCBG_07247Acyl_transf_3 domain-containing protein. (459 aa)
HCBG_06709Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (172 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (189 aa)
HCBG_06636Transcription factor SPT8. (626 aa)
HCBG_06531Transcription initiation factor TFIID complex 60 kDa subunit. (491 aa)
HCBG_06528Transcription factor TFIID complex subunit Taf11. (480 aa)
HCBG_06161Uncharacterized protein. (597 aa)
HCBG_06142Transcription termination factor 2. (1092 aa)
HCBG_06141Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (178 aa)
HCBG_05964Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1527 aa)
HCBG_05940Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (253 aa)
HCBG_05635C2HC5 zinc finger domain-containing protein. (518 aa)
HCBG_05466DNA repair and recombination protein RAD5B. (928 aa)
HCBG_05649SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (379 aa)
HCBG_05268Med12 domain-containing protein. (1601 aa)
HCBG_05185JmjC domain-containing protein. (461 aa)
HCBG_04185Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (753 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (256 aa)
HCBG_04531Uncharacterized protein. (117 aa)
HCBG_04377Uncharacterized protein. (156 aa)
HCBG_04329SAP30_Sin3_bdg domain-containing protein. (226 aa)
HCBG_03866Uncharacterized protein. (331 aa)
HCBG_03463Helicase C-terminal domain-containing protein. (1209 aa)
HCBG_03444Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1079 aa)
HCBG_03421Uncharacterized protein. (251 aa)
HCBG_03306Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1040 aa)
HCBG_03191TMF_TATA_bd domain-containing protein. (866 aa)
HCBG_02373DNA methyltransferase 1-associated protein DMAP1. (613 aa)
MED5Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1042 aa)
HCBG_02225Uncharacterized protein. (577 aa)
HCBG_02203PC4 domain-containing protein. (156 aa)
HCBG_03050Uncharacterized protein. (593 aa)
HCBG_02720WD domain-containing protein. (622 aa)
HCBG_02531Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (377 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (275 aa)
HCBG_09198SWIRM domain-containing protein. (371 aa)
HCBG_09145WD_REPEATS_REGION domain-containing protein. (573 aa)
HCBG_08704Uncharacterized protein. (395 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (694 aa)
HCBG_08392F-box domain-containing protein. (334 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (376 aa)
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
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