STRINGSTRING
HCBG_05961 HCBG_05961 HCBG_06075 HCBG_06075 HCBG_06160 HCBG_06160 HCBG_06164 HCBG_06164 HCBG_06195 HCBG_06195 HCBG_06376 HCBG_06376 HCBG_06452 HCBG_06452 HCBG_06458 HCBG_06458 HCBG_06465 HCBG_06465 HCBG_06545 HCBG_06545 HCBG_06600 HCBG_06600 HCBG_06858 HCBG_06858 HCBG_06969 HCBG_06969 HCBG_07031 HCBG_07031 MEF1 MEF1 HCBG_07132 HCBG_07132 HCBG_07351 HCBG_07351 HCBG_07532 HCBG_07532 HCBG_07713 HCBG_07713 HCBG_07893 HCBG_07893 HCBG_07958 HCBG_07958 HCBG_08335 HCBG_08335 HCBG_08344 HCBG_08344 HCBG_08459 HCBG_08459 GUF1 GUF1 HCBG_08635 HCBG_08635 HCBG_08793 HCBG_08793 HCBG_08802 HCBG_08802 HCBG_08848 HCBG_08848 HCBG_08876 HCBG_08876 HCBG_08903 HCBG_08903 HCBG_08942 HCBG_08942 HCBG_08959 HCBG_08959 HCBG_09002 HCBG_09002 TEF TEF HCBG_05944 HCBG_05944 HCBG_05916 HCBG_05916 HCBG_05844 HCBG_05844 HCBG_05586 HCBG_05586 HCBG_05579 HCBG_05579 HCBG_05553 HCBG_05553 HCBG_05480 HCBG_05480 HCBG_05458 HCBG_05458 HCBG_05319 HCBG_05319 HCBG_05282 HCBG_05282 HCBG_05133 HCBG_05133 HCBG_05078 HCBG_05078 HCBG_05054 HCBG_05054 HCBG_04869 HCBG_04869 HCBG_04793 HCBG_04793 HCBG_04280 HCBG_04280 HCBG_04241 HCBG_04241 HCBG_04692 HCBG_04692 HCBG_04667 HCBG_04667 HCBG_04646 HCBG_04646 HCBG_04573 HCBG_04573 HCBG_04522 HCBG_04522 HCBG_04516 HCBG_04516 HCBG_04510 HCBG_04510 HCBG_04454 HCBG_04454 HCBG_03848 HCBG_03848 HCBG_03842 HCBG_03842 HCBG_03712 HCBG_03712 HCBG_03659 HCBG_03659 HCBG_03593 HCBG_03593 HCBG_03398 HCBG_03398 HCBG_03372 HCBG_03372 HCBG_03301 HCBG_03301 HCBG_03216 HCBG_03216 HCBG_03203 HCBG_03203 SEY1 SEY1 HCBG_03184 HCBG_03184 HCBG_03167 HCBG_03167 HCBG_03133 HCBG_03133 HCBG_03126 HCBG_03126 HCBG_02379 HCBG_02379 HCBG_02302 HCBG_02302 HCBG_03098 HCBG_03098 HCBG_03036 HCBG_03036 HCBG_03035 HCBG_03035 HCBG_02984 HCBG_02984 HCBG_02983 HCBG_02983 HCBG_02967 HCBG_02967 HCBG_02850 HCBG_02850 HCBG_02768 HCBG_02768 HCBG_02727 HCBG_02727 HCBG_02716 HCBG_02716 HCBG_02715 HCBG_02715 HCBG_02445 HCBG_02445 HCBG_01708 HCBG_01708 HCBG_01644 HCBG_01644 HCBG_01595 HCBG_01595 HCBG_01569 HCBG_01569 HCBG_01545 HCBG_01545 HCBG_01497 HCBG_01497 HCBG_01446 HCBG_01446 HCBG_01270 HCBG_01270 HCBG_01264 HCBG_01264 HCBG_01251 HCBG_01251 HCBG_01229 HCBG_01229 HCBG_02186 HCBG_02186 HCBG_02185 HCBG_02185 HCBG_02056 HCBG_02056 MEF2 MEF2 HCBG_01120 HCBG_01120 HCBG_01031 HCBG_01031 HCBG_00972 HCBG_00972 HCBG_00970 HCBG_00970 HCBG_00819 HCBG_00819 HCBG_00754 HCBG_00754 HCBG_00753 HCBG_00753 ADK2 ADK2 HCBG_00588 HCBG_00588 HCBG_00363 HCBG_00363 HCBG_00281 HCBG_00281 HCBG_00084 HCBG_00084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCBG_05961Uncharacterized protein. (254 aa)
HCBG_06075ADP-ribosylation factor. (242 aa)
HCBG_06160GTP binding protein Bms1. (1177 aa)
HCBG_06164Elongation factor 2. (843 aa)
HCBG_06195Eukaryotic translation initiation factor 5B. (1072 aa)
HCBG_06376Vacuolar sorting-associated protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
HCBG_06452Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (388 aa)
HCBG_06458GTP cyclohydrolase I. (390 aa)
HCBG_06465Dynamin family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (827 aa)
HCBG_06545Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (527 aa)
HCBG_06600Rraga protein. (346 aa)
HCBG_06858Uncharacterized protein. (198 aa)
HCBG_06969Developmentally regulated GTP-binding protein. (367 aa)
HCBG_07031GTP-binding protein ypt5. (217 aa)
MEF1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (796 aa)
HCBG_07132ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (183 aa)
HCBG_07351Vacuolar sorting-associated protein. (285 aa)
HCBG_07532Uracil phosphoribosyltransferase. (263 aa)
HCBG_07713Rho3 GTPase. (193 aa)
HCBG_07893Chitin synthase. (303 aa)
HCBG_07958Uncharacterized protein. (325 aa)
HCBG_08335GTP-binding protein SAS1. (205 aa)
HCBG_08344Uncharacterized protein. (674 aa)
HCBG_08459Ras-like GTP-binding protein RYL2. (303 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (657 aa)
HCBG_08635tRNA modification GTPase GTPBP3. (615 aa)
HCBG_08793Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
HCBG_08802GTP-binding protein ypt3. (210 aa)
HCBG_08848GTP-binding protein ypt1. (205 aa)
HCBG_08876GTP cyclohydrolase II. (495 aa)
HCBG_08903Uncharacterized protein. (247 aa)
HCBG_08942Mitochondrial GTPase 1; Mitochondrial GTPase involved in assembly of the large ribosomal subunit. Plays a role in expression of the mitochondrial translational machinery; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (340 aa)
HCBG_08959Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (384 aa)
HCBG_09002Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
TEFElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (460 aa)
HCBG_05944Elongation factor Tu GTP binding domain-containing protein. (832 aa)
HCBG_05916Eukaryotic peptide chain release factor GTP-binding subunit. (724 aa)
HCBG_05844GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (341 aa)
HCBG_05586Tubulin gamma chain; Belongs to the tubulin family. (1133 aa)
HCBG_05579GTP cyclohydrolase II. (430 aa)
HCBG_05553Small G-protein GPA3. (338 aa)
HCBG_05480GTP-binding protein. (363 aa)
HCBG_05458Large subunit GTPase. (664 aa)
HCBG_05319Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (344 aa)
HCBG_05282Uncharacterized protein. (199 aa)
HCBG_05133ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (183 aa)
HCBG_05078Rho3 GTPase. (281 aa)
HCBG_05054Uncharacterized protein. (209 aa)
HCBG_04869Uncharacterized protein. (212 aa)
HCBG_04793U5 small nuclear ribonucleoprotein component. (990 aa)
HCBG_04280Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (666 aa)
HCBG_04241Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (565 aa)
HCBG_04692MIT domain-containing protein. (998 aa)
HCBG_04667Uncharacterized protein. (321 aa)
HCBG_04646Uncharacterized protein. (239 aa)
HCBG_04573PH domain-containing protein. (1486 aa)
HCBG_04522Eukaryotic translation initiation factor 5. (429 aa)
HCBG_04516mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (430 aa)
HCBG_04510Uncharacterized protein. (192 aa)
HCBG_04454Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (595 aa)
HCBG_03848Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (422 aa)
HCBG_03842GTP-binding protein Obg. (573 aa)
HCBG_03712Dynamin family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
HCBG_03659ADP-ribosylation factor. (845 aa)
HCBG_03593Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
HCBG_03398Mannose-1-phosphate guanylyltransferase. (374 aa)
HCBG_03372GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (408 aa)
HCBG_03301Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (394 aa)
HCBG_03216GTP-binding protein. (547 aa)
HCBG_03203GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (303 aa)
SEY1Protein SEY1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (873 aa)
HCBG_03184Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (441 aa)
HCBG_03167Dynamin GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (920 aa)
HCBG_03133Anucleate primary sterigmata protein B. (1931 aa)
HCBG_03126GTPase Ras2p. (362 aa)
HCBG_02379Rho GTPase Rho1. (192 aa)
HCBG_02302Small GTPase RHO1. (287 aa)
HCBG_03098Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (649 aa)
HCBG_03036GDP-mannose pyrophosphorylase A. (437 aa)
HCBG_03035Dynamin family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (822 aa)
HCBG_02984DUF1713 domain-containing protein. (389 aa)
HCBG_02983Small G-protein GPA2. (355 aa)
HCBG_02967GTP-binding protein. (414 aa)
HCBG_02850Signal sequence receptor alpha subunit. (914 aa)
HCBG_02768GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (213 aa)
HCBG_02727GTP-binding protein. (362 aa)
HCBG_02716Uncharacterized protein. (660 aa)
HCBG_02715Sde2_N_Ubi domain-containing protein. (317 aa)
HCBG_02445Mitochondrial initiation factor 2. (1027 aa)
HCBG_01708GTPase Rab7. (205 aa)
HCBG_01644GTP-binding protein. (638 aa)
HCBG_01595Translocation elongation factor. (1039 aa)
HCBG_01569Transmembrane GTPase fzo1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (937 aa)
HCBG_01545Septum-promoting GTP-binding protein. (348 aa)
HCBG_01497ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (182 aa)
HCBG_01446tRNA guanylyltransferase. (189 aa)
HCBG_01270GTP-binding protein GTR2. (398 aa)
HCBG_01264Molybdopterin cofactor biosynthetic protein. (747 aa)
HCBG_01251N-acetyltransferase domain-containing protein. (235 aa)
HCBG_01229ADP-ribosylation factor. (252 aa)
HCBG_02186WAPL domain-containing protein. (924 aa)
HCBG_02185Rheb small monomeric GTPase RhbA. (187 aa)
HCBG_02056Uncharacterized protein. (641 aa)
MEF2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (908 aa)
HCBG_01120Uncharacterized protein. (196 aa)
HCBG_01031Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (461 aa)
HCBG_00972Ribosome biogenesis protein TSR1. (819 aa)
HCBG_00970CobW/P47K family protein. (266 aa)
HCBG_00819Small GTPase RanA. (339 aa)
HCBG_00754Uncharacterized protein. (753 aa)
HCBG_00753Small COPII coat GTPase sar1; Belongs to the small GTPase superfamily. SAR1 family. (294 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (239 aa)
HCBG_00588Uncharacterized protein. (407 aa)
HCBG_00363Uncharacterized protein. (254 aa)
HCBG_00281Uncharacterized protein. (343 aa)
HCBG_00084Eukaryotic translation initiation factor 2 gamma subunit. (521 aa)
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.