35 items (Histoplasma capsulatum G186AR) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	HCBG_05226	N-acetyltransferase domain-containing protein. (234 aa)
	HCBG_06384	Farnesyl-pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (347 aa)
	HCBG_06591	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (728 aa)
	HCBG_06865	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (245 aa)
	HCBG_06981	Uncharacterized protein. (148 aa)
	HCBG_06726	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (475 aa)
	HCBG_07213	AB hydrolase-1 domain-containing protein. (413 aa)
	HCBG_07329	Squalene synthetase. (493 aa)
	HCBG_07474	Uncharacterized protein. (306 aa)
	HCBG_07716	Decaprenyl-diphosphate synthase subunit 1. (521 aa)
	HCBG_08666	Short-chain dehydrogenase/reductase. (375 aa)
	HCBG_08853	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (673 aa)
	HCBG_03424	Dehydrodolichyl diphosphate synthetase. (412 aa)
	HCBG_02341	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (406 aa)
	HCBG_03008	Actin patch protein. (877 aa)
	HCBG_02813	Short-chain dehydrogenase/reductase. (411 aa)
	HCBG_01410	Aldehyde reductase. (348 aa)
	HCBG_03591	DUF2236 domain-containing protein. (425 aa)
	HCBG_01353	Uncharacterized protein. (184 aa)
	HCBG_01972	Adenylate-forming enzyme AfeA. (557 aa)
	HCBG_00991	Hormone-sensitive lipase. (838 aa)
	HCBG_00649	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (80 aa)
	HCBG_00120	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (488 aa)
	HCBG_00414	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1160 aa)
	HCBG_03737	Uncharacterized protein. (387 aa)
	HCBG_04326	Cytochrome P450; Belongs to the cytochrome P450 family. (471 aa)
	HCBG_04066	AB hydrolase-1 domain-containing protein. (499 aa)
	HCBG_04208	DUF2236 domain-containing protein. (361 aa)
	HCBG_04226	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (531 aa)
	HCBG_04864	Uncharacterized protein. (325 aa)
	HCBG_04904	Uncharacterized protein. (523 aa)
	HCBG_04940	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (542 aa)
	HCBG_05052	Uncharacterized protein. (331 aa)
	HCBG_05097	Isopentenyl-diphosphate delta-isomerase. (272 aa)
	HCBG_05534	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (403 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCBG_00120	HCBG_00414	C0NAH4	C0NBB8	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.973
HCBG_00120	HCBG_02341	C0NAH4	C0NIT4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.991
HCBG_00120	HCBG_04904	C0NAH4	C0NP24	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Uncharacterized protein.	0.471
HCBG_00120	HCBG_04940	C0NAH4	C0NP60	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.960
HCBG_00120	HCBG_05097	C0NAH4	C0NPL7	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Isopentenyl-diphosphate delta-isomerase.	0.769
HCBG_00120	HCBG_05534	C0NAH4	C0NRA4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.592
HCBG_00120	HCBG_06384	C0NAH4	C0NTA4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Farnesyl-pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.612
HCBG_00120	HCBG_06591	C0NAH4	C0NTW1	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.607
HCBG_00120	HCBG_06726	C0NAH4	C0NUW2	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.912
HCBG_00120	HCBG_07329	C0NAH4	C0NVZ9	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Squalene synthetase.	0.665
HCBG_00120	HCBG_08853	C0NAH4	C0P0D4	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.607
HCBG_00414	HCBG_00120	C0NBB8	C0NAH4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.973
HCBG_00414	HCBG_02341	C0NBB8	C0NIT4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.891
HCBG_00414	HCBG_02813	C0NBB8	C0NHJ1	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Short-chain dehydrogenase/reductase.	0.439
HCBG_00414	HCBG_04226	C0NBB8	C0NN99	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.457
HCBG_00414	HCBG_04904	C0NBB8	C0NP24	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein.	0.645
HCBG_00414	HCBG_04940	C0NBB8	C0NP60	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.724
HCBG_00414	HCBG_05097	C0NBB8	C0NPL7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Isopentenyl-diphosphate delta-isomerase.	0.758
HCBG_00414	HCBG_05534	C0NBB8	C0NRA4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.689
HCBG_00414	HCBG_06384	C0NBB8	C0NTA4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Farnesyl-pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.716