22 items (Histoplasma capsulatum G186AR) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCBG_03374	Uncharacterized protein; Belongs to the GST superfamily. (680 aa)
	HCBG_03166	Glucosamine 6-phosphate synthetase. (377 aa)
	HCBG_03091	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (319 aa)
	HCBG_01438	Glutathione transferase; Belongs to the GST superfamily. (275 aa)
	HCBG_01313	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (475 aa)
	HCBG_01218	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily. (250 aa)
	HCBG_00220	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (262 aa)
	HCBG_05243	Uncharacterized protein. (166 aa)
	HCBG_05202	Glutamate-cysteine ligase. (678 aa)
	HCBG_05688	Gamma-glutamyltranspeptidase. (628 aa)
	HCBG_05248	Glutamate-cysteine ligase regulatory subunit. (318 aa)
	HCBG_06017	WD domain-containing protein. (980 aa)
	HCBG_06493	Glutathione S-transferase; Belongs to the GST superfamily. (213 aa)
	HCBG_07387	Glutamine amidotransferase subunit pdxT. (261 aa)
	HCBG_07884	Glutathione S-transferase; Belongs to the GST superfamily. (256 aa)
	HCBG_05468	Glutathione synthetase. (516 aa)
	HCBG_08684	Elongation factor 1-gamma; Belongs to the GST superfamily. (399 aa)
	HCBG_08487	Cytosolic non-specific dipeptidase. (568 aa)
	HCBG_08895	Uncharacterized protein. (337 aa)
	HCBG_05010	Glutathione S-transferase. (396 aa)
	HCBG_04982	Glutathione transferase; Belongs to the GST superfamily. (303 aa)
	HCBG_04650	Glutathione S-transferase; Belongs to the GST superfamily. (331 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCBG_00220	HCBG_03374	C0NAS4	C0NJP4	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein; Belongs to the GST superfamily.	0.830
HCBG_00220	HCBG_05468	C0NAS4	C0NR38	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione synthetase.	0.925
HCBG_00220	HCBG_05688	C0NAS4	C0NQA0	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltranspeptidase.	0.824
HCBG_00220	HCBG_06493	C0NAS4	C0NTL3	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione S-transferase; Belongs to the GST superfamily.	0.566
HCBG_00220	HCBG_07884	C0NAS4	C0NY90	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione S-transferase; Belongs to the GST superfamily.	0.931
HCBG_00220	HCBG_08895	C0NAS4	C0P0G5	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.566
HCBG_01218	HCBG_01313	C0NEA2	C0NEJ7	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.652
HCBG_01218	HCBG_01438	C0NEA2	C0NEX2	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione transferase; Belongs to the GST superfamily.	0.709
HCBG_01218	HCBG_03091	C0NEA2	C0NIB9	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.428
HCBG_01218	HCBG_03374	C0NEA2	C0NJP4	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Uncharacterized protein; Belongs to the GST superfamily.	0.757
HCBG_01218	HCBG_04650	C0NEA2	C0NMC0	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione S-transferase; Belongs to the GST superfamily.	0.527
HCBG_01218	HCBG_04982	C0NEA2	C0NPA2	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione transferase; Belongs to the GST superfamily.	0.709
HCBG_01218	HCBG_05010	C0NEA2	C0NPD0	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione S-transferase.	0.527
HCBG_01218	HCBG_05468	C0NEA2	C0NR38	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione synthetase.	0.693
HCBG_01218	HCBG_05688	C0NEA2	C0NQA0	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Gamma-glutamyltranspeptidase.	0.530
HCBG_01218	HCBG_06493	C0NEA2	C0NTL3	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione S-transferase; Belongs to the GST superfamily.	0.677
HCBG_01218	HCBG_07884	C0NEA2	C0NY90	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Glutathione S-transferase; Belongs to the GST superfamily.	0.757
HCBG_01218	HCBG_08684	C0NEA2	C0NZV5	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Elongation factor 1-gamma; Belongs to the GST superfamily.	0.885
HCBG_01218	HCBG_08895	C0NEA2	C0P0G5	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	Uncharacterized protein.	0.677
HCBG_01313	HCBG_01218	C0NEJ7	C0NEA2	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Maleylacetoacetate isomerase MaiA; Belongs to the GST superfamily.	0.652