56 items (Histoplasma capsulatum G186AR) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCBG_00525	RING-6 finger domain-containing protein. (462 aa)
	HCBG_04658	Protein kinase domain-containing protein. (932 aa)
	HCBG_04128	Uncharacterized protein. (401 aa)
	HCBG_04129	Uncharacterized protein. (77 aa)
	HCBG_05478	Cpc-3 protein. (1588 aa)
	HCBG_05641	Carbon catabolite-derepressing protein kinase. (701 aa)
	HCBG_05845	Spindle assembly checkpoint protein SLDB. (374 aa)
	HCBG_05874	Uncharacterized protein. (264 aa)
	HCBG_06055	Spindle assembly checkpoint protein SLDA. (1297 aa)
	HCBG_06245	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (790 aa)
	HCBG_06314	ERCC4 domain-containing protein. (627 aa)
	HCBG_06399	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (764 aa)
	HCBG_06963	Phosphoprotein phosphatase A. (617 aa)
	HCBG_07208	Serine/threonine-protein kinase. (673 aa)
	HCBG_07595	Cell division control protein; Belongs to the CDC6/cdc18 family. (619 aa)
	HCBG_08105	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
	HCBG_08185	Structural maintenance of chromosomes protein. (1192 aa)
	HCBG_08253	Spc7 domain-containing protein. (1568 aa)
	HCBG_08328	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (344 aa)
	HCBG_08537	MRC1 domain-containing protein. (1498 aa)
	HCBG_08600	HORMA domain-containing protein. (229 aa)
	HCBG_08703	RNA-dependent RNA polymerase. (1240 aa)
	HCBG_08862	Uncharacterized protein. (995 aa)
	HCBG_09009	Serine/threonine-protein kinase. (1106 aa)
	HCBG_09182	Serine/threonine-protein kinase. (703 aa)
	HCBG_00089	Uncharacterized protein. (836 aa)
	HCBG_00154	Cell division cycle protein. (598 aa)
	HCBG_00185	Dual specificity protein kinase. (811 aa)
	HCBG_00661	Cell division control protein. (466 aa)
	HCBG_00752	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (309 aa)
	HCBG_00837	Stress protein p66. (622 aa)
	HCBG_00913	Uncharacterized protein. (532 aa)
	HCBG_02057	DUF625 domain-containing protein. (928 aa)
	HCBG_02076	Serine/threonine-protein kinase Chk2. (849 aa)
	HCBG_01461	WD domain-containing protein. (616 aa)
	HCBG_01570	BRCT domain-containing protein. (891 aa)
	HCBG_01584	Uncharacterized protein. (448 aa)
	HCBG_01585	FHA domain-containing protein. (641 aa)
	HCBG_04419	Uncharacterized protein. (196 aa)
	HCBG_03942	Crossover junction endonuclease mus81. (644 aa)
	HCBG_03905	Spindle assembly checkpoint component mad1. (733 aa)
	HCBG_03715	Cell cycle control protein. (967 aa)
	HCBG_03481	WD domain-containing protein. (891 aa)
	HCBG_03112	Serine/threonine-protein kinase Hsk1. (501 aa)
	HCBG_02999	Tyrosine-protein phosphatase CDC14. (617 aa)
	HCBG_02832	Checkpoint protein; Belongs to the HUS1 family. (364 aa)
	HCBG_02824	Uncharacterized protein. (1082 aa)
	HCBG_02812	CLPTM1 domain-containing protein. (648 aa)
	HCBG_02745	Serine/threonine-protein kinase chk1. (468 aa)
	HCBG_02730	HORMA domain-containing protein. (745 aa)
	HCBG_02536	Calcium/calmodulin-dependent protein kinase; Belongs to the protein kinase superfamily. (414 aa)
	HCBG_01917	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa)
	HCBG_01722	Serine/threonine-protein phosphatase. (441 aa)
	HCBG_01706	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (530 aa)
	HCBG_01637	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2794 aa)
	HCBG_01626	STE family protein kinase. (517 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCBG_00089	HCBG_00154	C0NAE3	C0NAK8	Uncharacterized protein.	Cell division cycle protein.	0.669
HCBG_00089	HCBG_01461	C0NAE3	C0NEZ5	Uncharacterized protein.	WD domain-containing protein.	0.669
HCBG_00089	HCBG_03481	C0NAE3	C0NK01	Uncharacterized protein.	WD domain-containing protein.	0.669
HCBG_00089	HCBG_03905	C0NAE3	C0NL75	Uncharacterized protein.	Spindle assembly checkpoint component mad1.	0.701
HCBG_00089	HCBG_05845	C0NAE3	C0NRR5	Uncharacterized protein.	Spindle assembly checkpoint protein SLDB.	0.842
HCBG_00089	HCBG_06055	C0NAE3	C0NSC5	Uncharacterized protein.	Spindle assembly checkpoint protein SLDA.	0.835
HCBG_00089	HCBG_08600	C0NAE3	C0NZM0	Uncharacterized protein.	HORMA domain-containing protein.	0.827
HCBG_00154	HCBG_00089	C0NAK8	C0NAE3	Cell division cycle protein.	Uncharacterized protein.	0.669
HCBG_00154	HCBG_00752	C0NAK8	C0NCA6	Cell division cycle protein.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.751
HCBG_00154	HCBG_00913	C0NAK8	C0NCR7	Cell division cycle protein.	Uncharacterized protein.	0.438
HCBG_00154	HCBG_01461	C0NAK8	C0NEZ5	Cell division cycle protein.	WD domain-containing protein.	0.922
HCBG_00154	HCBG_01722	C0NAK8	C0NFQ6	Cell division cycle protein.	Serine/threonine-protein phosphatase.	0.601
HCBG_00154	HCBG_01917	C0NAK8	C0NGA1	Cell division cycle protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.653
HCBG_00154	HCBG_02745	C0NAK8	C0NHC3	Cell division cycle protein.	Serine/threonine-protein kinase chk1.	0.436
HCBG_00154	HCBG_02999	C0NAK8	C0NI27	Cell division cycle protein.	Tyrosine-protein phosphatase CDC14.	0.970
HCBG_00154	HCBG_03905	C0NAK8	C0NL75	Cell division cycle protein.	Spindle assembly checkpoint component mad1.	0.951
HCBG_00154	HCBG_04658	C0NAK8	C0NMC8	Cell division cycle protein.	Protein kinase domain-containing protein.	0.611
HCBG_00154	HCBG_05845	C0NAK8	C0NRR5	Cell division cycle protein.	Spindle assembly checkpoint protein SLDB.	0.955
HCBG_00154	HCBG_06055	C0NAK8	C0NSC5	Cell division cycle protein.	Spindle assembly checkpoint protein SLDA.	0.973
HCBG_00154	HCBG_06399	C0NAK8	C0NTB9	Cell division cycle protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.701