STRINGSTRING
HCBG_00102 HCBG_00102 HCBG_00120 HCBG_00120 HCBG_00189 HCBG_00189 HCBG_00260 HCBG_00260 HCBG_00278 HCBG_00278 HCBG_00405 HCBG_00405 HCBG_00414 HCBG_00414 HCBG_00649 HCBG_00649 HCBG_00653 HCBG_00653 HCBG_00668 HCBG_00668 HCBG_00778 HCBG_00778 HCBG_00791 HCBG_00791 HCBG_00945 HCBG_00945 HCBG_00991 HCBG_00991 HCBG_01021 HCBG_01021 HCBG_01075 HCBG_01075 HCBG_01079 HCBG_01079 HCBG_01142 HCBG_01142 HCBG_01946 HCBG_01946 HCBG_02011 HCBG_02011 HCBG_02041 HCBG_02041 HCBG_02044 HCBG_02044 HCBG_02051 HCBG_02051 HCBG_02092 HCBG_02092 HCBG_02128 HCBG_02128 HCBG_01217 HCBG_01217 HCBG_01234 HCBG_01234 HCBG_01417 HCBG_01417 HCBG_01424 HCBG_01424 HCBG_01440 HCBG_01440 HCBG_01454 HCBG_01454 HCBG_01556 HCBG_01556 HCBG_01615 HCBG_01615 HCBG_01619 HCBG_01619 HCBG_01624 HCBG_01624 HCBG_01635 HCBG_01635 HCBG_01654 HCBG_01654 HCBG_01659 HCBG_01659 HCBG_01818 HCBG_01818 HCBG_02448 HCBG_02448 HCBG_02452 HCBG_02452 HCBG_02560 HCBG_02560 HCBG_02598 HCBG_02598 HCBG_02656 HCBG_02656 HCBG_02675 HCBG_02675 HCBG_02694 HCBG_02694 HCBG_02756 HCBG_02756 HCBG_02788 HCBG_02788 HCBG_02813 HCBG_02813 HCBG_03014 HCBG_03014 HCBG_03090 HCBG_03090 HCBG_03091 HCBG_03091 HCBG_02204 HCBG_02204 HCBG_02205 HCBG_02205 HCBG_02264 HCBG_02264 HCBG_02337 HCBG_02337 HCBG_02341 HCBG_02341 HCBG_03121 HCBG_03121 HCBG_03150 HCBG_03150 HCBG_03155 HCBG_03155 HCBG_03257 HCBG_03257 HCBG_03395 HCBG_03395 HCBG_03399 HCBG_03399 HCBG_03424 HCBG_03424 HCBG_03446 HCBG_03446 HCBG_03542 HCBG_03542 HCBG_03591 HCBG_03591 HCBG_03602 HCBG_03602 HCBG_03608 HCBG_03608 HCBG_03737 HCBG_03737 HCBG_03808 HCBG_03808 HCBG_03871 HCBG_03871 HCBG_04301 HCBG_04301 HCBG_04308 HCBG_04308 HCBG_04383 HCBG_04383 HCBG_04384 HCBG_04384 HCBG_04421 HCBG_04421 HCBG_04487 HCBG_04487 HCBG_04523 HCBG_04523 HCBG_04562 HCBG_04562 HCBG_04585 HCBG_04585 HCBG_03956 HCBG_03956 HCBG_03987 HCBG_03987 HCBG_04064 HCBG_04064 HCBG_04066 HCBG_04066 HCBG_04177 HCBG_04177 HCBG_04208 HCBG_04208 HCBG_04235 HCBG_04235 HCBG_04734 HCBG_04734 HCBG_04794 HCBG_04794 HCBG_04835 HCBG_04835 HCBG_04898 HCBG_04898 HCBG_04899 HCBG_04899 HCBG_04936 HCBG_04936 HCBG_04940 HCBG_04940 HCBG_05053 HCBG_05053 cprA cprA HCBG_05130 HCBG_05130 HCBG_05244 HCBG_05244 HCBG_05712 HCBG_05712 HCBG_05753 HCBG_05753 HCBG_05764 HCBG_05764 HCBG_05406 HCBG_05406 HCBG_05624 HCBG_05624 HCBG_05924 HCBG_05924 HCBG_05943 HCBG_05943 HCBG_06083 HCBG_06083 HCBG_06102 HCBG_06102 HCBG_06193 HCBG_06193 HCBG_06243 HCBG_06243 HCBG_06307 HCBG_06307 HCBG_06316 HCBG_06316 HCBG_06319 HCBG_06319 HCBG_06342 HCBG_06342 HCBG_06348 HCBG_06348 HCBG_06430 HCBG_06430 HCBG_06458 HCBG_06458 HCBG_06474 HCBG_06474 HCBG_06540 HCBG_06540 HCBG_06542 HCBG_06542 HCBG_06620 HCBG_06620 HCBG_06865 HCBG_06865 HCBG_06896 HCBG_06896 HCBG_06941 HCBG_06941 HCBG_06948 HCBG_06948 HCBG_06981 HCBG_06981 HCBG_07008 HCBG_07008 HCBG_06694 HCBG_06694 HCBG_06726 HCBG_06726 HCBG_07167 HCBG_07167 HCBG_07213 HCBG_07213 HCBG_07229 HCBG_07229 HCBG_07310 HCBG_07310 HCBG_07329 HCBG_07329 HCBG_07384 HCBG_07384 HCBG_07439 HCBG_07439 HCBG_07495 HCBG_07495 HCBG_07507 HCBG_07507 HCBG_07543 HCBG_07543 HCBG_07564 HCBG_07564 HCBG_07589 HCBG_07589 HCBG_07597 HCBG_07597 HCBG_07601 HCBG_07601 HCBG_07604 HCBG_07604 HCBG_08099 HCBG_08099 HCBG_08109 HCBG_08109 HCBG_08154 HCBG_08154 HCBG_07836 HCBG_07836 HCBG_07850 HCBG_07850 HCBG_07898 HCBG_07898 HCBG_07668 HCBG_07668 HCBG_08275 HCBG_08275 HCBG_08346 HCBG_08346 HCBG_08349 HCBG_08349 HCBG_08351 HCBG_08351 HCBG_08357 HCBG_08357 HCBG_08417 HCBG_08417 HCBG_08458 HCBG_08458 HCBG_08505 HCBG_08505 HCBG_08645 HCBG_08645 HCBG_08666 HCBG_08666 HCBG_08852 HCBG_08852 HCBG_08900 HCBG_08900 HCBG_08907 HCBG_08907 HCBG_08973 HCBG_08973 HCBG_08998 HCBG_08998 HCBG_09033 HCBG_09033 HCBG_09040 HCBG_09040 HCBG_09041 HCBG_09041 HCBG_09059 HCBG_09059 HCBG_09081 HCBG_09081 HCBG_09094 HCBG_09094 HCBG_09098 HCBG_09098 HCBG_09106 HCBG_09106 HCBG_09117 HCBG_09117 HCBG_09147 HCBG_09147 HCBG_09179 HCBG_09179 HCBG_09213 HCBG_09213 HCBG_09220 HCBG_09220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCBG_00102INSIG domain-containing protein. (440 aa)
HCBG_00120Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (488 aa)
HCBG_00189Polyphenoloxidase. (638 aa)
HCBG_00260Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (502 aa)
HCBG_00278D-lactate dehydrogenase. (608 aa)
HCBG_00405Cytochrome P450 sterol 14 alpha-demethylase; Belongs to the cytochrome P450 family. (515 aa)
HCBG_004143-hydroxy-3-methylglutaryl coenzyme A reductase. (1160 aa)
HCBG_00649Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (80 aa)
HCBG_00653Uncharacterized protein. (183 aa)
HCBG_00668Pyridoxine kinase. (406 aa)
HCBG_00778Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa)
HCBG_00791NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (321 aa)
HCBG_00945DJ-1/PfpI family protein. (227 aa)
HCBG_00991Hormone-sensitive lipase. (838 aa)
HCBG_01021F-box domain-containing protein. (621 aa)
HCBG_01075Uncharacterized protein. (820 aa)
HCBG_01079EXPERA domain-containing protein. (263 aa)
HCBG_01142Zn(2)-C6 fungal-type domain-containing protein. (758 aa)
HCBG_01946Myo-inositol oxygenase. (311 aa)
HCBG_02011IPPc domain-containing protein. (432 aa)
HCBG_02041Alcohol dehydrogenase. (349 aa)
HCBG_02044Squalene epoxidase. (484 aa)
HCBG_02051Phosphatase. (1119 aa)
HCBG_02092Pyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family. (320 aa)
HCBG_02128Uncharacterized protein. (312 aa)
HCBG_01217Fumarylacetoacetase. (429 aa)
HCBG_01234Long-chain-alcohol oxidase. (631 aa)
HCBG_014176-chlorohydroxyquinol-1,2-dioxygenase. (355 aa)
HCBG_01424Uncharacterized protein. (487 aa)
HCBG_01440Hydroxyacyl-Coenzyme A dehydrogenase type II. (256 aa)
HCBG_01454Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (438 aa)
HCBG_01556TIP120 domain-containing protein. (1225 aa)
HCBG_01615Hydroxyacylglutathione hydrolase. (685 aa)
HCBG_01619Uncharacterized protein. (494 aa)
HCBG_01624Enoyl-CoA hydratase. (149 aa)
HCBG_01635Dihydroxyacetone kinase. (596 aa)
HCBG_01654Pyruvate decarboxylase. (592 aa)
HCBG_01659Uracil-5-carboxylate decarboxylase; Belongs to the metallo-dependent hydrolases superfamily. (381 aa)
HCBG_018187-dehydrosterol-delta 7-reductase. (426 aa)
HCBG_02448Haloacid dehalogenase. (235 aa)
HCBG_02452Neutral ceramidase. (764 aa)
HCBG_02560PH domain-containing protein. (1467 aa)
HCBG_025985-oxoprolinase. (1312 aa)
HCBG_02656Serine palmitoyltransferase. (507 aa)
HCBG_02675C-3 sterol dehydrogenase/C-4 decarboxylase. (355 aa)
HCBG_02694Oxidoreductase. (196 aa)
HCBG_02756Tyrosinase. (801 aa)
HCBG_02788Glycosyltransferase. (1340 aa)
HCBG_02813Short-chain dehydrogenase/reductase. (411 aa)
HCBG_030143',5'-bisphosphate nucleotidase. (353 aa)
HCBG_03090Alcohol dehydrogenase. (495 aa)
HCBG_03091Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (319 aa)
HCBG_022045-oxoprolinase. (516 aa)
HCBG_022055-oxoprolinase. (465 aa)
HCBG_02264Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (458 aa)
HCBG_02337Tyrosine phosphatase. (254 aa)
HCBG_02341Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (406 aa)
HCBG_03121Uncharacterized protein. (308 aa)
HCBG_03150Uncharacterized protein. (345 aa)
HCBG_03155N-acetyltransferase domain-containing protein. (219 aa)
HCBG_03257Beta-lactamase. (410 aa)
HCBG_03395Glycerol kinase; Belongs to the FGGY kinase family. (545 aa)
HCBG_033993-ketosteroid reductase. (472 aa)
HCBG_03424Dehydrodolichyl diphosphate synthetase. (412 aa)
HCBG_03446DlpA domain-containing protein. (242 aa)
HCBG_03542C-24(28) sterol reductase. (472 aa)
HCBG_03591DUF2236 domain-containing protein. (425 aa)
HCBG_03602Sterol desaturase; Belongs to the sterol desaturase family. (334 aa)
HCBG_03608Sphingosine kinase. (508 aa)
HCBG_03737Uncharacterized protein. (387 aa)
HCBG_03808EXPERA domain-containing protein. (231 aa)
HCBG_03871Uncharacterized protein. (116 aa)
HCBG_04301Ergosterol biosynthetic protein. (133 aa)
HCBG_04308Uncharacterized protein. (413 aa)
HCBG_04383S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
HCBG_04384Inositol-3-phosphate synthase. (532 aa)
HCBG_04421Oxidoreductase. (568 aa)
HCBG_04487N-acetyltransferase domain-containing protein. (208 aa)
HCBG_04523Thiamine-phosphate pyrophosphorylase. (520 aa)
HCBG_04562Glutamine amidotransferase subunit pdxT. (279 aa)
HCBG_04585O-acyltransferase. (515 aa)
HCBG_03956Retinal dehydrogenase; Belongs to the aldehyde dehydrogenase family. (536 aa)
HCBG_03987FAD binding domain-containing protein. (514 aa)
HCBG_04064ThiJ/PfpI family protein. (232 aa)
HCBG_04066AB hydrolase-1 domain-containing protein. (499 aa)
HCBG_04177Enoyl-CoA hydratase. (275 aa)
HCBG_04208DUF2236 domain-containing protein. (361 aa)
HCBG_04235Sterol desaturase; Belongs to the sterol desaturase family. (263 aa)
HCBG_04734Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
HCBG_04794Acetyl-coa acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (241 aa)
HCBG_04835Kinase; Belongs to the inositol phosphokinase (IPK) family. (457 aa)
HCBG_04898Pyridox_oxase_2 domain-containing protein. (192 aa)
HCBG_04899Uncharacterized protein. (375 aa)
HCBG_04936Pyridoxamine 5'-phosphate oxidase. (396 aa)
HCBG_04940Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (542 aa)
HCBG_05053Pkinase_fungal domain-containing protein. (365 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (694 aa)
HCBG_05130Amidase. (641 aa)
HCBG_05244C-8 sterol isomerase. (223 aa)
HCBG_05712Thiamine biosynthesis protein. (343 aa)
HCBG_05753Serine/threonine-protein kinase. (1156 aa)
HCBG_05764DUF775 domain-containing protein. (269 aa)
HCBG_05406Alcohol dehydrogenase. (353 aa)
HCBG_05624Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
HCBG_05924BZIP domain-containing protein. (554 aa)
HCBG_05943Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (137 aa)
HCBG_06083Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (334 aa)
HCBG_06102NUDIX/MutT family protein. (158 aa)
HCBG_06193Cytochrome P450 sterol C-22 desaturase; Belongs to the cytochrome P450 family. (533 aa)
HCBG_06243Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
HCBG_063075-oxoprolinase. (1360 aa)
HCBG_06316Kinase; Belongs to the inositol phosphokinase (IPK) family. (1572 aa)
HCBG_06319Uncharacterized protein. (793 aa)
HCBG_06342Type I inositol-1,4,5-trisphosphate 5-phosphatase. (1250 aa)
HCBG_06348Actin interacting protein. (551 aa)
HCBG_06430Alcohol dehydrogenase. (340 aa)
HCBG_06458GTP cyclohydrolase I. (390 aa)
HCBG_06474ThiJ/PfpI family protein. (258 aa)
HCBG_06540Isopenicillin N-CoA epimerase. (398 aa)
HCBG_06542Oxidoreductase. (281 aa)
HCBG_06620Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (322 aa)
HCBG_06865Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (245 aa)
HCBG_06896O-acyltransferase. (541 aa)
HCBG_06941Uncharacterized protein. (244 aa)
HCBG_06948C-14 sterol reductase. (503 aa)
HCBG_06981Uncharacterized protein. (148 aa)
HCBG_07008Uncharacterized protein. (161 aa)
HCBG_06694Pyruvate decarboxylase. (546 aa)
HCBG_067263-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (475 aa)
HCBG_07167Uncharacterized protein. (670 aa)
HCBG_07213AB hydrolase-1 domain-containing protein. (413 aa)
HCBG_07229GPR/FUN34 family protein. (287 aa)
HCBG_07310Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (172 aa)
HCBG_07329Squalene synthetase. (493 aa)
HCBG_07384Macrophage binding protein. (244 aa)
HCBG_07439Scytalone dehydratase. (162 aa)
HCBG_07495Uncharacterized protein. (77 aa)
HCBG_07507Acetyltransferase. (207 aa)
HCBG_07543FAD binding domain-containing protein. (575 aa)
HCBG_075642-nitropropane dioxygenase. (376 aa)
HCBG_07589Alcohol dehydrogenase. (368 aa)
HCBG_07597Uncharacterized protein. (332 aa)
HCBG_07601N-acetyltransferase domain-containing protein. (184 aa)
HCBG_076043-dehydroshikimate dehydratase. (277 aa)
HCBG_08099Phosphomethylpyrimidine kinase THI20. (488 aa)
HCBG_08109Mannitol-1-phosphate dehydrogenase. (388 aa)
HCBG_08154Photo-regulated tyrosinase. (797 aa)
HCBG_07836Uncharacterized protein. (487 aa)
HCBG_07850Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (377 aa)
HCBG_07898Delta(24(24(1)))-sterol reductase. (552 aa)
HCBG_07668Glycerol kinase; Belongs to the FGGY kinase family. (510 aa)
HCBG_08275Enoyl-CoA hydratase. (240 aa)
HCBG_08346C-4 methylsterol oxidase; Belongs to the sterol desaturase family. (259 aa)
HCBG_08349Uncharacterized protein. (279 aa)
HCBG_08351Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1501 aa)
HCBG_08357Inositol-1-monophosphatase. (333 aa)
HCBG_08417Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (380 aa)
HCBG_08458Cytochrome b2. (513 aa)
HCBG_08505Sucrase/ferredoxin domain-containing protein. (344 aa)
HCBG_08645Sucrose cleavage family protein. (369 aa)
HCBG_08666Short-chain dehydrogenase/reductase. (375 aa)
HCBG_08852Cytochrome P450; Belongs to the cytochrome P450 family. (505 aa)
HCBG_08900Triacylglycerol lipase. (519 aa)
HCBG_08907D-arabinitol dehydrogenase. (379 aa)
HCBG_08973AMP dependent synthetase and ligase. (547 aa)
HCBG_08998Triacylglycerol lipase. (607 aa)
HCBG_09033Nonribosomal peptide synthetase. (1955 aa)
HCBG_09040Long-chain-fatty-acid-CoA ligase. (589 aa)
HCBG_09041Acetylase. (439 aa)
HCBG_09059C-3 sterol dehydrogenase/C-4 decarboxylase. (426 aa)
HCBG_09081Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family. (1260 aa)
HCBG_09094SacI domain and endonuclease/exonuclease/phosphatase. (1241 aa)
HCBG_09098Diacylglycerol O-acyltransferase. (466 aa)
HCBG_09106Uncharacterized protein; Belongs to the cytochrome P450 family. (544 aa)
HCBG_09117Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (388 aa)
HCBG_09147C-5 sterol desaturase; Belongs to the sterol desaturase family. (356 aa)
HCBG_09179FAD-binding FR-type domain-containing protein. (396 aa)
HCBG_09213Oxidoreductase. (318 aa)
HCBG_09220Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (239 aa)
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
Server load: low (38%) [HD]