44 items (Histoplasma capsulatum G186AR) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCBG_00592	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa)
	HCBG_04678	Thioredoxin domain-containing protein. (211 aa)
	HCBG_04643	MOSC domain-containing protein. (398 aa)
	HCBG_04479	Glyoxal oxidase. (843 aa)
	HCBG_04357	Uncharacterized protein. (340 aa)
	HCBG_04328	MOSC domain-containing protein. (485 aa)
	HCBG_03680	Uncharacterized protein. (287 aa)
	HCBG_03650	Cu-Zn superoxide dismutase. (287 aa)
	HCBG_03468	Fatty acid oxygenase. (1084 aa)
	HCBG_00675	Cytochrome b561 domain-containing protein. (743 aa)
	HCBG_01313	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (475 aa)
	HCBG_01806	Uncharacterized protein. (404 aa)
	HCBG_01821	HEME_HALOPEROXIDASE domain-containing protein. (445 aa)
	HCBG_02666	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (191 aa)
	HCBG_02841	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (760 aa)
	HCBG_02876	Alcohol dehydrogenase. (346 aa)
	HCBG_02995	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
	HCBG_03111	Protein-L-isoaspartate O-methyltransferase. (243 aa)
	HCBG_03179	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (211 aa)
	HCBG_03374	Uncharacterized protein; Belongs to the GST superfamily. (680 aa)
	HCBG_03391	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (234 aa)
	HCBG_08549	F-box domain-containing protein. (376 aa)
	HCBG_08399	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (728 aa)
	HCBG_07884	Glutathione S-transferase; Belongs to the GST superfamily. (256 aa)
	HCBG_08202	Manganese superoxide dismutase. (306 aa)
	HCBG_08047	Superoxide dismutase 1 copper chaperone. (244 aa)
	HCBG_08029	Peroxidase; Belongs to the peroxidase family. (303 aa)
	HCBG_08028	Uncharacterized protein. (145 aa)
	HCBG_07136	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (503 aa)
	HCBG_07093	Uncharacterized protein. (152 aa)
	HCBG_06890	Glutaredoxin domain-containing protein. (107 aa)
	HCBG_06622	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	HCBG_06614	Fatty acid oxygenase. (1138 aa)
	HCBG_06612	HEME_HALOPEROXIDASE domain-containing protein. (276 aa)
	HCBG_06552	Alcohol dehydrogenase. (451 aa)
	HCBG_06026	Sulphydryl oxidase Sox. (385 aa)
	HCBG_05629	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (166 aa)
	HCBG_05248	Glutamate-cysteine ligase regulatory subunit. (318 aa)
	HCBG_05128	Animal heme peroxidase. (1116 aa)
	HCBG_04724	Uncharacterized protein. (245 aa)
	HCBG_04264	Peroxidase; Belongs to the peroxidase family. (374 aa)
	HCBG_04262	Thioredoxin. (337 aa)
	HCBG_04171	Thioredoxin reductase. (697 aa)
	HCBG_03960	Thiol-specific antioxidant. (222 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCBG_00592	HCBG_02876	C0NBU6	C0NHQ4	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.	Alcohol dehydrogenase.	0.703
HCBG_00592	HCBG_06552	C0NBU6	C0NTS2	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.	Alcohol dehydrogenase.	0.703
HCBG_00675	HCBG_02841	C0NC29	C0NHL9	Cytochrome b561 domain-containing protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.498
HCBG_00675	HCBG_04724	C0NC29	C0NNJ4	Cytochrome b561 domain-containing protein.	Uncharacterized protein.	0.482
HCBG_00675	HCBG_06622	C0NC29	C0NTZ2	Cytochrome b561 domain-containing protein.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.514
HCBG_00675	HCBG_07136	C0NC29	C0NVF6	Cytochrome b561 domain-containing protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.498
HCBG_00675	HCBG_08399	C0NC29	C0NZ19	Cytochrome b561 domain-containing protein.	Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.	0.498
HCBG_01313	HCBG_02666	C0NEJ7	C0NH44	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.801
HCBG_01313	HCBG_02841	C0NEJ7	C0NHL9	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.519
HCBG_01313	HCBG_02995	C0NEJ7	C0NI23	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.893
HCBG_01313	HCBG_03374	C0NEJ7	C0NJP4	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Uncharacterized protein; Belongs to the GST superfamily.	0.851
HCBG_01313	HCBG_03650	C0NEJ7	C0NKH0	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Cu-Zn superoxide dismutase.	0.442
HCBG_01313	HCBG_03960	C0NEJ7	C0NMI3	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thiol-specific antioxidant.	0.964
HCBG_01313	HCBG_04171	C0NEJ7	C0NN44	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thioredoxin reductase.	0.928
HCBG_01313	HCBG_04262	C0NEJ7	C0NND5	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thioredoxin.	0.450
HCBG_01313	HCBG_04264	C0NEJ7	C0NND7	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxidase; Belongs to the peroxidase family.	0.601
HCBG_01313	HCBG_04678	C0NEJ7	C0NME8	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Thioredoxin domain-containing protein.	0.511
HCBG_01313	HCBG_05248	C0NEJ7	C0NQ18	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Glutamate-cysteine ligase regulatory subunit.	0.543
HCBG_01313	HCBG_05629	C0NEJ7	C0NRJ9	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.767
HCBG_01313	HCBG_06622	C0NEJ7	C0NTZ2	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.557