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HCBG_03834 HCBG_03834 VPS10 VPS10 HCBG_03568 HCBG_03568 HCBG_03482 HCBG_03482 HCBG_03481 HCBG_03481 HCBG_03411 HCBG_03411 HCBG_03331 HCBG_03331 HCBG_03306 HCBG_03306 HCBG_03304 HCBG_03304 HCBG_03299 HCBG_03299 HCBG_03239 HCBG_03239 HCBG_03193 HCBG_03193 HCBG_02222 HCBG_02222 HCBG_03097 HCBG_03097 PAN2 PAN2 HCBG_02782 HCBG_02782 HCBG_02728 HCBG_02728 HCBG_02720 HCBG_02720 HCBG_02645 HCBG_02645 HCBG_02595 HCBG_02595 HCBG_01917 HCBG_01917 HCBG_01817 HCBG_01817 HCBG_01804 HCBG_01804 HCBG_01743 HCBG_01743 HCBG_01695 HCBG_01695 HCBG_01676 HCBG_01676 HCBG_01669 HCBG_01669 HCBG_01593 HCBG_01593 HCBG_01581 HCBG_01581 HCBG_01544 HCBG_01544 HCBG_01519 HCBG_01519 HCBG_04036 HCBG_04036 HCBG_04189 HCBG_04189 HCBG_04267 HCBG_04267 HCBG_04708 HCBG_04708 HCBG_04709 HCBG_04709 HCBG_04751 HCBG_04751 HCBG_04802 HCBG_04802 HCBG_04812 HCBG_04812 HCBG_04897 HCBG_04897 HCBG_05093 HCBG_05093 HCBG_05122 HCBG_05122 HCBG_05729 HCBG_05729 PRT1 PRT1 HCBG_05753 HCBG_05753 HCBG_05755 HCBG_05755 HCBG_01461 HCBG_01461 HCBG_01453 HCBG_01453 HCBG_01449 HCBG_01449 HCBG_01268 HCBG_01268 HCBG_02122 HCBG_02122 HCBG_01958 HCBG_01958 HCBG_01950 HCBG_01950 HCBG_04432 HCBG_04432 HCBG_01103 HCBG_01103 HCBG_01057 HCBG_01057 HCBG_01002 HCBG_01002 HCBG_05778 HCBG_05778 HCBG_05295 HCBG_05295 HCBG_05321 HCBG_05321 HCBG_00961 HCBG_00961 HCBG_00083 HCBG_00083 YTM1 YTM1 HCBG_00154 HCBG_00154 HCBG_00245 HCBG_00245 TIF34 TIF34 HCBG_00268 HCBG_00268 HCBG_00311 HCBG_00311 HCBG_00444 HCBG_00444 HCBG_00487 HCBG_00487 HCBG_00566 HCBG_00566 HCBG_00616 HCBG_00616 HCBG_00623 HCBG_00623 HCBG_00641 HCBG_00641 HCBG_00648 HCBG_00648 HCBG_00659 HCBG_00659 HCBG_00678 HCBG_00678 HCBG_00707 HCBG_00707 TRM82 TRM82 HCBG_00837 HCBG_00837 HCBG_00853 HCBG_00853 HCBG_00933 HCBG_00933 HCBG_01937 HCBG_01937 HCBG_03899 HCBG_03899 HCBG_00080 HCBG_00080 HCBG_00077 HCBG_00077 HCBG_01203 HCBG_01203 CIA1 CIA1 HCBG_00971 HCBG_00971 HCBG_05339 HCBG_05339 ERB1 ERB1 PAC1 PAC1 HCBG_05603 HCBG_05603 HCBG_05792 HCBG_05792 HCBG_05845 HCBG_05845 HCBG_05856 HCBG_05856 HCBG_05963 HCBG_05963 HCBG_06017 HCBG_06017 HCBG_06085 HCBG_06085 HCBG_06196 HCBG_06196 HCBG_06246 HCBG_06246 HCBG_06277 HCBG_06277 HCBG_06296 HCBG_06296 HCBG_06320 HCBG_06320 HCBG_06342 HCBG_06342 HCBG_06378 HCBG_06378 HCBG_06451 HCBG_06451 HCBG_06453 HCBG_06453 HCBG_06457 HCBG_06457 HCBG_06619 HCBG_06619 HCBG_06629 HCBG_06629 HCBG_06636 HCBG_06636 HCBG_06863 HCBG_06863 HCBG_06886 HCBG_06886 HCBG_06994 HCBG_06994 HCBG_06687 HCBG_06687 HCBG_07216 HCBG_07216 HCBG_07239 HCBG_07239 HCBG_07368 HCBG_07368 HCBG_07399 HCBG_07399 HCBG_08112 HCBG_08112 HCBG_08146 HCBG_08146 HCBG_08192 HCBG_08192 HCBG_08220 HCBG_08220 HCBG_07693 HCBG_07693 HCBG_07723 HCBG_07723 HCBG_07748 HCBG_07748 HCBG_07891 HCBG_07891 HCBG_07914 HCBG_07914 HCBG_07951 HCBG_07951 HCBG_08350 HCBG_08350 HCBG_08439 HCBG_08439 HCBG_08494 HCBG_08494 HCBG_08561 HCBG_08561 HCBG_08744 HCBG_08744 HCBG_08819 HCBG_08819 HCBG_08845 HCBG_08845 HCBG_08960 HCBG_08960 HCBG_09136 HCBG_09136 HCBG_09145 HCBG_09145 HCBG_09158 HCBG_09158 HCBG_03965 HCBG_03965 HCBG_04584 HCBG_04584 HCBG_04495 HCBG_04495
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCBG_03834Peroxin 7. (358 aa)
VPS10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1497 aa)
HCBG_03568WD domain-containing protein. (376 aa)
HCBG_03482Utp12 domain-containing protein. (902 aa)
HCBG_03481WD domain-containing protein. (891 aa)
HCBG_03411F-box and WD domain-containing protein. (885 aa)
HCBG_03331WD domain-containing protein. (454 aa)
HCBG_03306Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1040 aa)
HCBG_03304WD domain-containing protein. (1445 aa)
HCBG_03299DUF1339 domain-containing protein. (1052 aa)
HCBG_03239Carboxy-cis,cis-muconate cyclase. (360 aa)
HCBG_03193Pre-mRNA-splicing factor. (458 aa)
HCBG_02222Protein transporter SEC13; Belongs to the WD repeat SEC13 family. (315 aa)
HCBG_03097Catabolite repression protein creC. (598 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1208 aa)
HCBG_02782Pre-mRNA-splicing factor rse1. (1209 aa)
HCBG_02728Cell division control protein. (1054 aa)
HCBG_02720WD domain-containing protein. (622 aa)
HCBG_02645DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (539 aa)
HCBG_02595WD_REPEATS_REGION domain-containing protein. (306 aa)
HCBG_01917Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa)
HCBG_01817U4/U6 small nuclear ribonucleoprotein Prp4. (545 aa)
HCBG_01804Cytoplasmic dynein intermediate chain. (692 aa)
HCBG_01743WD domain-containing protein. (1040 aa)
HCBG_01695Small G-beta protein GPB. (353 aa)
HCBG_01676WD domain-containing protein. (990 aa)
HCBG_01669WD domain-containing protein. (362 aa)
HCBG_01593Cell cycle control protein. (476 aa)
HCBG_01581Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
HCBG_01544Ribosome assembly protein RRB1. (495 aa)
HCBG_01519U3 small nucleolar RNA associated protein. (447 aa)
HCBG_04036WD domain-containing protein. (393 aa)
HCBG_04189Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (934 aa)
HCBG_04267Nuclear pore complex subunit; Belongs to the WD repeat SEC13 family. (415 aa)
HCBG_04708Uncharacterized protein. (788 aa)
HCBG_04709WD domain-containing protein. (348 aa)
HCBG_04751WD domain-containing protein. (1068 aa)
HCBG_04802CPSF_A domain-containing protein. (1408 aa)
HCBG_04812Uncharacterized protein. (438 aa)
HCBG_04897WD domain-containing protein. (500 aa)
HCBG_05093Uncharacterized protein. (1626 aa)
HCBG_05122DNA damage-binding protein 1a. (1201 aa)
HCBG_05729WD domain-containing protein. (515 aa)
PRT1Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (737 aa)
HCBG_05753Serine/threonine-protein kinase. (1156 aa)
HCBG_05755Peptidyl-prolyl cis-trans isomerase cypE. (629 aa)
HCBG_01461WD domain-containing protein. (616 aa)
HCBG_01453WD domain-containing protein. (340 aa)
HCBG_01449WD domain-containing protein. (115 aa)
HCBG_01268WD domain-containing protein. (564 aa)
HCBG_02122Uncharacterized protein. (697 aa)
HCBG_01958Ribosome assembly protein SQT1. (522 aa)
HCBG_01950WD domain-containing protein. (597 aa)
HCBG_04432WD domain-containing protein. (657 aa)
HCBG_01103F-box and WD repeat-containing protein. (724 aa)
HCBG_01057Sulfur metabolite repression control protein. (703 aa)
HCBG_01002WD domain-containing protein. (1028 aa)
HCBG_05778WD_REPEATS_REGION domain-containing protein. (1213 aa)
HCBG_05295Uncharacterized protein. (1332 aa)
HCBG_05321WD domain-containing protein. (326 aa)
HCBG_00961Protein transporter SEC31. (1274 aa)
HCBG_00083Uncharacterized protein. (487 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (490 aa)
HCBG_00154Cell division cycle protein. (598 aa)
HCBG_00245Uncharacterized protein. (438 aa)
TIF34Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (340 aa)
HCBG_00268Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1216 aa)
HCBG_00311U5 snRNP-specific protein. (359 aa)
HCBG_00444F-box domain-containing protein. (1116 aa)
HCBG_00487WD domain-containing protein. (1387 aa)
HCBG_00566Uncharacterized protein. (1234 aa)
HCBG_00616Periodic tryptophan protein. (559 aa)
HCBG_00623WD domain-containing protein. (961 aa)
HCBG_00641Transcription initiation factor TFIID subunit 5. (715 aa)
HCBG_00648Uncharacterized protein. (1107 aa)
HCBG_00659WD domain-containing protein. (1098 aa)
HCBG_00678Uncharacterized protein. (437 aa)
HCBG_00707Vps8 domain-containing protein. (1599 aa)
TRM82tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (538 aa)
HCBG_00837Stress protein p66. (622 aa)
HCBG_00853U3 snoRNA associated protein. (644 aa)
HCBG_00933NUP214 domain-containing protein. (1472 aa)
HCBG_01937WD domain-containing protein. (1031 aa)
HCBG_03899WD domain-containing protein. (1364 aa)
HCBG_00080U3 small nucleolar RNA-associated protein. (967 aa)
HCBG_00077Ribosomal RNA-processing protein. (641 aa)
HCBG_01203Coronin; Belongs to the WD repeat coronin family. (557 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (485 aa)
HCBG_00971U3 snoRNP-associated protein Utp7. (545 aa)
HCBG_05339Poly(A)+ RNA export protein. (362 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (788 aa)
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (456 aa)
HCBG_05603WD domain-containing protein. (1467 aa)
HCBG_05792WD domain-containing protein. (839 aa)
HCBG_05845Spindle assembly checkpoint protein SLDB. (374 aa)
HCBG_05856Guanine nucleotide-binding protein. (421 aa)
HCBG_05963WD domain-containing protein. (717 aa)
HCBG_06017WD domain-containing protein. (980 aa)
HCBG_06085WD domain-containing protein. (537 aa)
HCBG_06196Thermotolerance protein. (1301 aa)
HCBG_06246F-box and WD domain-containing protein. (1154 aa)
HCBG_06277WD domain-containing protein. (1520 aa)
HCBG_06296WD domain-containing protein. (659 aa)
HCBG_06320E3 ubiquitin-protein ligase PEP5. (955 aa)
HCBG_06342Type I inositol-1,4,5-trisphosphate 5-phosphatase. (1250 aa)
HCBG_06378WD domain-containing protein. (828 aa)
HCBG_06451Periodic tryptophan protein. (929 aa)
HCBG_06453WD domain-containing protein. (376 aa)
HCBG_06457Chromatin assembly factor 1 subunit C. (435 aa)
HCBG_06619Uncharacterized protein. (2525 aa)
HCBG_06629DUF1620 domain-containing protein. (1415 aa)
HCBG_06636Transcription factor SPT8. (626 aa)
HCBG_06863Uncharacterized protein. (770 aa)
HCBG_06886Uncharacterized protein. (1558 aa)
HCBG_06994Uncharacterized protein. (945 aa)
HCBG_06687WD_REPEATS_REGION domain-containing protein. (1001 aa)
HCBG_07216Chromatin assembly factor 1 subunit B. (763 aa)
HCBG_07239WD_REPEATS_REGION domain-containing protein. (1041 aa)
HCBG_07368F-box domain-containing protein. (722 aa)
HCBG_07399Vacuolar sorting-associated protein. (1288 aa)
HCBG_08112Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (846 aa)
HCBG_08146WD domain-containing protein. (488 aa)
HCBG_08192WD domain-containing protein. (419 aa)
HCBG_08220Pre-mRNA-splicing factor. (583 aa)
HCBG_07693WD domain-containing protein. (572 aa)
HCBG_07723Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (708 aa)
HCBG_07748Uncharacterized protein. (672 aa)
HCBG_07891Uncharacterized protein. (1509 aa)
HCBG_07914WD_REPEATS_REGION domain-containing protein. (849 aa)
HCBG_07951F-box domain-containing protein. (621 aa)
HCBG_08350U3 small nucleolar RNA-associated protein. (1129 aa)
HCBG_08439NACHT and WD domain-containing protein. (1653 aa)
HCBG_08494WD domain-containing protein. (1029 aa)
HCBG_08561U3 small nucleolar RNA-associated protein. (571 aa)
HCBG_08744DUF2415 domain-containing protein. (754 aa)
HCBG_08819Uncharacterized protein. (484 aa)
HCBG_08845WD domain-containing protein. (1066 aa)
HCBG_08960SVP1-like protein. (370 aa)
HCBG_09136Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (364 aa)
HCBG_09145WD_REPEATS_REGION domain-containing protein. (573 aa)
HCBG_09158RNA polymerase II 90 kDa subunit. (878 aa)
HCBG_03965WD domain-containing protein. (616 aa)
HCBG_04584Polyadenylation factor subunit 2. (648 aa)
HCBG_04495WD domain-containing protein. (738 aa)
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
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