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HCBG_03194 HCBG_03194 HCBG_09185 HCBG_09185 HCBG_09083 HCBG_09083 HCBG_08948 HCBG_08948 HCBG_08826 HCBG_08826 HCBG_08497 HCBG_08497 HCBG_08179 HCBG_08179 HCBG_08098 HCBG_08098 MCM7 MCM7 HCBG_07595 HCBG_07595 HCBG_07522 HCBG_07522 HCBG_07404 HCBG_07404 HCBG_07367 HCBG_07367 HCBG_07244 HCBG_07244 HCBG_06849 HCBG_06849 HCBG_06624 HCBG_06624 HCBG_06389 HCBG_06389 HCBG_06190 HCBG_06190 HCBG_06116 HCBG_06116 HCBG_06113 HCBG_06113 HCBG_06061 HCBG_06061 HCBG_06030 HCBG_06030 HCBG_06002 HCBG_06002 HCBG_05986 HCBG_05986 HCBG_05834 HCBG_05834 HCBG_05625 HCBG_05625 HCBG_05293 HCBG_05293 HCBG_05152 HCBG_05152 HCBG_05136 HCBG_05136 HCBG_04188 HCBG_04188 HCBG_04238 HCBG_04238 HCBG_04779 HCBG_04779 HCBG_04807 HCBG_04807 HCBG_04916 HCBG_04916 HCBG_04933 HCBG_04933 HCBG_05109 HCBG_05109 HCBG_00239 HCBG_00239 HCBG_00381 HCBG_00381 HCBG_00597 HCBG_00597 HCBG_00691 HCBG_00691 HCBG_00823 HCBG_00823 HCBG_00873 HCBG_00873 HCBG_01975 HCBG_01975 HCBG_02094 HCBG_02094 HCBG_01370 HCBG_01370 HCBG_01606 HCBG_01606 HCBG_01632 HCBG_01632 HCBG_02535 HCBG_02535 HCBG_02765 HCBG_02765 HCBG_03100 HCBG_03100 HCBG_02231 HCBG_02231 HCBG_03112 HCBG_03112 HCBG_03217 HCBG_03217 HCBG_03336 HCBG_03336 HCBG_03381 HCBG_03381 HCBG_03554 HCBG_03554 HCBG_03804 HCBG_03804 HCBG_03936 HCBG_03936 HCBG_04110 HCBG_04110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCBG_03194Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (836 aa)
HCBG_09185Uncharacterized protein. (168 aa)
HCBG_09083Serine/threonine-protein kinase crk1; Belongs to the protein kinase superfamily. (413 aa)
HCBG_08948Serine/threonine phosphatase. (431 aa)
HCBG_08826AAA_16 domain-containing protein. (570 aa)
HCBG_08497DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
HCBG_08179Origin recognition complex subunit. (757 aa)
HCBG_08098DNA polymerase. (1458 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (811 aa)
HCBG_07595Cell division control protein; Belongs to the CDC6/cdc18 family. (619 aa)
HCBG_07522G2/mitotic-specific cyclin cdc13; Belongs to the cyclin family. (558 aa)
HCBG_07404Ubiquitin. (152 aa)
HCBG_07367Uncharacterized protein. (142 aa)
HCBG_07244G1/S-specific cyclin CLN1; Belongs to the cyclin family. (419 aa)
HCBG_06849Cell division cycle protein. (803 aa)
HCBG_06624Uncharacterized protein. (100 aa)
HCBG_06389DNA helicase; Belongs to the MCM family. (706 aa)
HCBG_06190DNA helicase; Belongs to the MCM family. (887 aa)
HCBG_06116DnaJ domain-containing protein. (331 aa)
HCBG_06113OB-fold nucleic acid binding domain-containing protein. (278 aa)
HCBG_06061M-phase inducer phosphatase. (537 aa)
HCBG_06030Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (324 aa)
HCBG_06002Uncharacterized protein. (106 aa)
HCBG_05986G1/S regulator. (676 aa)
HCBG_05834Uncharacterized protein. (448 aa)
HCBG_05625NLPC_P60 domain-containing protein. (208 aa)
HCBG_05293Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (606 aa)
HCBG_05152Chromo domain-containing protein. (414 aa)
HCBG_05136DNA helicase; Belongs to the MCM family. (882 aa)
HCBG_04188TPR domain-containing protein. (445 aa)
HCBG_04238CDK-activating kinase assembly factor MAT1. (379 aa)
HCBG_04779Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (113 aa)
HCBG_04807Origin recognition complex subunit. (686 aa)
HCBG_04916DNA helicase; Belongs to the MCM family. (965 aa)
HCBG_04933CBFD_NFYB_HMF domain-containing protein. (199 aa)
HCBG_05109Single-stranded DNA binding protein p30 subunit. (276 aa)
HCBG_00239Cyclin-dependent protein kinase PhoA; Belongs to the protein kinase superfamily. (310 aa)
HCBG_00381CCHC-type domain-containing protein. (313 aa)
HCBG_00597Cyclin-dependent protein kinase PhoA; Belongs to the protein kinase superfamily. (399 aa)
HCBG_00691DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
HCBG_00823DNA polymerase epsilon subunit B. (748 aa)
HCBG_00873DNA helicase; Belongs to the MCM family. (1017 aa)
HCBG_01975Cyclin-dependent protein kinase regulator; Belongs to the cyclin family. (489 aa)
HCBG_02094Origin recognition complex subunit. (556 aa)
HCBG_01370DNA replication initiation factor Cdc45. (865 aa)
HCBG_01606DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (667 aa)
HCBG_01632Uncharacterized protein. (117 aa)
HCBG_02535DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2232 aa)
HCBG_02765Uncharacterized protein. (564 aa)
HCBG_03100Zds_C domain-containing protein. (870 aa)
HCBG_02231BZIP domain-containing protein. (303 aa)
HCBG_03112Serine/threonine-protein kinase Hsk1. (501 aa)
HCBG_03217CBFD_NFYB_HMF domain-containing protein. (310 aa)
HCBG_03336G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (499 aa)
HCBG_03381Uncharacterized protein. (608 aa)
HCBG_03554Uncharacterized protein. (320 aa)
HCBG_03804Uncharacterized protein. (160 aa)
HCBG_03936UDP-galactopyranose mutase. (533 aa)
HCBG_04110Ubiquitin. (305 aa)
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
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