43 items (Histoplasma capsulatum G186AR) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	HCBG_07955	Aldo/keto reductase. (194 aa)
	HCBG_00485	Heavy metal tolerance protein. (934 aa)
	HCBG_00506	Aldo-keto reductase. (280 aa)
	HCBG_00625	Uncharacterized protein. (474 aa)
	HCBG_00772	NAD(P)H-dependent D-xylose reductase. (164 aa)
	HCBG_01944	Uncharacterized protein. (114 aa)
	HCBG_02078	Vacuolar metal resistance ABC transporter. (1536 aa)
	HCBG_02103	Leptomycin B resistance protein. (1366 aa)
	HCBG_02177	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (183 aa)
	HCBG_01255	GMP synthase. (896 aa)
	HCBG_01273	Aldo/keto reductase. (320 aa)
	HCBG_01432	Uncharacterized protein. (274 aa)
	HCBG_02560	PH domain-containing protein. (1467 aa)
	HCBG_02747	Acetyl-coenzyme A synthetase. (560 aa)
	HCBG_02788	Glycosyltransferase. (1340 aa)
	HCBG_06634	ATP-dependent bile acid permease. (1677 aa)
	HCBG_07063	ATP-dependent bile acid permease. (1579 aa)
	HCBG_08165	ABC protein. (1441 aa)
	HCBG_07838	ATP-dependent permease MDL1. (829 aa)
	HCBG_07839	Nucleoside transporter. (619 aa)
	HCBG_00423	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
	HCBG_08487	Cytosolic non-specific dipeptidase. (568 aa)
	HCBG_08881	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (317 aa)
	HCBG_09032	Uncharacterized protein. (1321 aa)
	HCBG_02863	AB hydrolase-1 domain-containing protein. (267 aa)
	HCBG_02241	Multidrug resistance protein. (1270 aa)
	HCBG_02245	Uncharacterized protein. (277 aa)
	HCBG_03291	Uncharacterized protein. (442 aa)
	HCBG_03317	Aldehyde reductase. (313 aa)
	HCBG_03443	Velvet domain-containing protein. (899 aa)
	HCBG_04362	ABC multidrug transporter. (1294 aa)
	HCBG_04373	NADP-dependent glycerol dehydrogenase. (330 aa)
	HCBG_04383	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa)
	HCBG_04675	Integral membrane protein. (408 aa)
	HCBG_04010	Gamma-glutamyltranspeptidase. (600 aa)
	HCBG_04232	ABC a-pheromone efflux pump AtrD. (1416 aa)
	HCBG_05688	Gamma-glutamyltranspeptidase. (628 aa)
	HCBG_05318	Guanylate kinase. (768 aa)
	HCBG_05436	Adenosine kinase. (350 aa)
	HCBG_05538	Adenosine deaminase. (367 aa)
	HCBG_06017	WD domain-containing protein. (980 aa)
	HCBG_06515	Nucleoside diphosphate kinase. (152 aa)
	HCBG_00033	Uncharacterized protein. (655 aa)

Your Current Organism:

Histoplasma capsulatum G186AR

NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCBG_00423	HCBG_01255	C0NBC7	C0NED9	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	GMP synthase.	0.998
HCBG_00423	HCBG_02177	C0NBC7	C0NE84	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.971
HCBG_00423	HCBG_02245	C0NBC7	C0NII8	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Uncharacterized protein.	0.806
HCBG_00423	HCBG_05318	C0NBC7	C0NQN8	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Guanylate kinase.	0.806
HCBG_00423	HCBG_05436	C0NBC7	C0NR06	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Adenosine kinase.	0.713
HCBG_00423	HCBG_05538	C0NBC7	C0NRA8	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Adenosine deaminase.	0.698
HCBG_00423	HCBG_06515	C0NBC7	C0NTN5	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Nucleoside diphosphate kinase.	0.620
HCBG_00423	HCBG_07839	C0NBC7	C0NY45	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Nucleoside transporter.	0.454
HCBG_00423	HCBG_08881	C0NBC7	C0P0G2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.870
HCBG_00485	HCBG_02078	C0NBI9	C0NDY5	Heavy metal tolerance protein.	Vacuolar metal resistance ABC transporter.	0.481
HCBG_00485	HCBG_02103	C0NBI9	C0NE10	Heavy metal tolerance protein.	Leptomycin B resistance protein.	0.469
HCBG_00485	HCBG_02241	C0NBI9	C0NII4	Heavy metal tolerance protein.	Multidrug resistance protein.	0.469
HCBG_00485	HCBG_02863	C0NBI9	C0NHP1	Heavy metal tolerance protein.	AB hydrolase-1 domain-containing protein.	0.469
HCBG_00485	HCBG_04232	C0NBI9	C0NNA5	Heavy metal tolerance protein.	ABC a-pheromone efflux pump AtrD.	0.469
HCBG_00485	HCBG_04362	C0NBI9	C0NLI2	Heavy metal tolerance protein.	ABC multidrug transporter.	0.469
HCBG_00485	HCBG_06634	C0NBI9	C0NU04	Heavy metal tolerance protein.	ATP-dependent bile acid permease.	0.481
HCBG_00485	HCBG_07063	C0NBI9	C0NUN2	Heavy metal tolerance protein.	ATP-dependent bile acid permease.	0.481
HCBG_00485	HCBG_07838	C0NBI9	C0NY44	Heavy metal tolerance protein.	ATP-dependent permease MDL1.	0.504
HCBG_00485	HCBG_08165	C0NBI9	C0NXH3	Heavy metal tolerance protein.	ABC protein.	0.481
HCBG_00485	HCBG_09032	C0NBI9	C0P0V2	Heavy metal tolerance protein.	Uncharacterized protein.	0.469