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| | argH | L-argininosuccinate lyase. (466 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa) |
| | fbaA | Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa) |
| | MAE_32950 | Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. (485 aa) |
| | MAE_33380 | Hypothetical protein. (272 aa) |
| | hemH-2 | Ferrochelatase; Belongs to the ferrochelatase family. (379 aa) |
| | MAE_34870 | Putative phosphoketolase. (806 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) |
| | MAE_35160 | Glutathione-dependent formaldehyde-activating enzyme; GFA. (135 aa) |
| | cobD | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (326 aa) |
| | MAE_36470 | Hypothetical protein. (382 aa) |
| | MAE_36560 | Beta-type carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (217 aa) |
| | MAE_36580 | Beta-type carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (282 aa) |
| | MAE_36750 | Pyruvate decarboxylase isozyme 1. (547 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (139 aa) |
| | pyrF | Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (233 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1018 aa) |
| | hemB-2 | Porphobilinogen synthase; 5-aminolevulinate dehydratase; Belongs to the ALAD family. (328 aa) |
| | MAE_39970 | Pterin-4-alpha-carbinolamine dehydratase. (116 aa) |
| | speH | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (135 aa) |
| | MAE_41400 | Transketolase, central region. (732 aa) |
| | MAE_41860 | Glutamate decarboxylase. (185 aa) |
| | rlpA | RlpA-like lipoprotein precursor; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (249 aa) |
| | thiC | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (460 aa) |
| | cpcS-2 | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (179 aa) |
| | cya1 | Adenylate cyclase. (340 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (296 aa) |
| | MAE_45320 | Pantothenate metabolism flavoprotein. (419 aa) |
| | menB | 1,4-dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (277 aa) |
| | speA | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (679 aa) |
| | MAE_47280 | Protein of unknown function UPF0047. (139 aa) |
| | rbcS | Ribulose bisphosphate carboxylase small subunit. (111 aa) |
| | rbcL | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. (471 aa) |
| | MAE_48080 | Heat domain containing protein. (247 aa) |
| | MAE_48260 | L-cysteine/cystine lyase. (404 aa) |
| | mtnB | Aldolase/epimerase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (205 aa) |
| | ycf58 | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (193 aa) |
| | pheA | Prephenate dehydratase. (284 aa) |
| | MAE_49340 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (888 aa) |
| | apcE | Phycobilisome core-membrane linker polypeptide; Belongs to the phycobilisome linker protein family. (901 aa) |
| | nnrD | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (522 aa) |
| | MAE_51980 | Putative phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family. (490 aa) |
| | hisF | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa) |
| | MAE_53090 | Hypothetical protein; Catalyzes the decarbonylation of fatty aldehydes to alkanes. (231 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | MAE_54830 | Hypothetical protein. (617 aa) |
| | hemD | uroporphyrinogen-III C-methyltransferase and uroporphyrinogen-III synthase fusion protein; A fusion protein between CobA/CorA and HemD; gene:hemD or cobA. (505 aa) |
| | MAE_56560 | Bacilysin biosynthesis protein BacA homolog. (210 aa) |
| | cpcS-3 | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (170 aa) |
| | rfbB-3 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (358 aa) |
| | fabZ | (3R)-hydroxymyristol acyl carrier protein dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (159 aa) |
| | MAE_58210 | Glyoxalase/bleomycin resistance protein/dioxygenase. (158 aa) |
| | menC | O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (321 aa) |
| | thrC | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (369 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (209 aa) |
| | MAE_60750 | PBS lyase heat-like repeat. (396 aa) |
| | MAE_60880 | Glycoside hydrolase family 57. (304 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa) |
| | MAE_61240 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (869 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (166 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (375 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa) |
| | MAE_02910 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa) |
| | cpcS | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (184 aa) |
| | gmd | GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (317 aa) |
| | moaA | Molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | cofG | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (295 aa) |
| | cbiX | Cobalamin biosynthesis protein. (236 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (540 aa) |
| | ccmA | Carboxysome formation protein. (351 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | phrA | DNA photolyase. (474 aa) |
| | cpcT1 | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (194 aa) |
| | MAE_07920 | HEAT domain protein repeat-containing protein. (224 aa) |
| | MAE_07950 | HEAT domain protein repeat-containing protein. (191 aa) |
| | murQ | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (306 aa) |
| | MAE_08810 | Hypothetical protein. (206 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (387 aa) |
| | cpcT2 | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (200 aa) |
| | cynS | Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (145 aa) |
| | rfbG | CDP-glucose 4,6-dehydratase. (378 aa) |
| | MAE_11020 | NAD-dependent epimerase/dehydratase. (352 aa) |
| | MAE_11470 | Hypothetical protein; Belongs to the LarC family. (418 aa) |
| | MAE_11790 | Putative oxidoreductase; Belongs to the UbiD family. (501 aa) |
| | MAE_12110 | 6-pyruvoyl-tetrahydropterin synthase homolog. (155 aa) |
| | mtnW | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily. (386 aa) |
| | MAE_14310 | Carbonic anhydrase precursor. (242 aa) |
| | MAE_15060 | Membrane-bound lytic transglycosylase A. (373 aa) |
| | ecaB | Periplasmic beta-type carbonic anhydrase. (241 aa) |
| | MAE_15840 | Hypothetical protein. (402 aa) |
| | MAE_17060 | Threonine synthase. (434 aa) |
| | MAE_17450 | Hypothetical protein. (434 aa) |
| | trpB | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa) |
| | rfbB | dTDP-glucose 4,6-dehydratase. (308 aa) |
| | trpE | Anthranilate synthase component I. (445 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | MAE_19860 | AraD-like aldolase/epimerase. (203 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa) |
| | cpcT3 | Hypothetical protein; Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins. (202 aa) |
| | hemB | 5-aminolevulinate dehydratase; Porphobilinogen synthase; Belongs to the ALAD family. (325 aa) |
| | MAE_23250 | Lactoylglutathione lyase. (130 aa) |
| | trpE-2 | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] (506 aa) |
| | trpG | Anthranilate synthase component II. (195 aa) |
| | ribBA | Riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (558 aa) |
| | MAE_25150 | Glyoxalase/bleomycin resistance protein/dioxygenase. (120 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (285 aa) |
| | dacA | Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (306 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (467 aa) |
| | MAE_25720 | Deoxyribodipyrimidine photolyase-related protein. (507 aa) |
| | queE | Hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (205 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (366 aa) |
| | cpcF | Phycocyanin alpha-subunit phycocyanobilin lyase. (207 aa) |
| | cpcE | Phycocyanin alpha-subunit phycocyanobilin lyase. (270 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (477 aa) |
| | ilvD | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (561 aa) |
| | ribA | Riboflavin biosynthesis protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (428 aa) |
| | gmd-2 | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (360 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | ilvA | L-threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa) |
