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| | MAE_01980 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (458 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (236 aa) |
| | MAE_02620 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (813 aa) |
| | nirA | Ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (321 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa) |
| | MAE_03940 | Pyruvate kinase; Belongs to the pyruvate kinase family. (509 aa) |
| | MAE_05230 | Citrate synthase; Belongs to the citrate synthase family. (379 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (331 aa) |
| | cofG | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (295 aa) |
| | acoB | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | MAE_05990 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (441 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (540 aa) |
| | MAE_06360 | Carboxymethylenebutenolidase. (244 aa) |
| | fumC | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | gltB | NADH-dependent glutamate synthase large subunit. (1524 aa) |
| | accA | acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (329 aa) |
| | gdhA | Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (431 aa) |
| | glnN | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (723 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (325 aa) |
| | MAE_11030 | Transketolase-like protein. (274 aa) |
| | MAE_11040 | Transketolase-like protein. (303 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (240 aa) |
| | tpi | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (230 aa) |
| | MAE_12590 | Ammonium transport protein. (291 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (273 aa) |
| | MAE_13670 | Succinate dehydrogenase iron-sulphur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (327 aa) |
| | cysE | Serine acetyltransferase. (319 aa) |
| | cysK | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (326 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (276 aa) |
| | gltD | NADH-dependent glutamate synthase small subunit. (494 aa) |
| | MAE_14970 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) |
| | MAE_15220 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (475 aa) |
| | leuB-2 | 3-isopropylmalate dehydrogenase. (362 aa) |
| | argD | N-acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (427 aa) |
| | comB | 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (241 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (524 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa) |
| | MAE_17060 | Threonine synthase. (434 aa) |
| | sir | Ferredoxin-sulfite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (645 aa) |
| | sat | Sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family. (389 aa) |
| | MAE_17590 | Phosphoenolpyruvate synthase. (718 aa) |
| | nirA-2 | Ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (513 aa) |
| | MAE_18450 | Glucokinase. (305 aa) |
| | glnA | Glutamate--ammonia ligase. (473 aa) |
| | MAE_19860 | AraD-like aldolase/epimerase. (203 aa) |
| | MAE_21280 | Glutathione-dependent formaldehyde dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | hemB | 5-aminolevulinate dehydratase; Porphobilinogen synthase; Belongs to the ALAD family. (325 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | fbp | Fructose-1,6-bisphosphatase. (348 aa) |
| | MAE_24190 | glutamyl-tRNA(Gln) amidotransferase subunit A. (438 aa) |
| | MAE_25030 | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa) |
| | MAE_25340 | Succinate-semialdehyde dehydrogenase [NAD(P)+]. (454 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (467 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (348 aa) |
| | MAE_27980 | Pyruvate kinase; Belongs to the pyruvate kinase family. (591 aa) |
| | glsF | Ferredoxin-dependent glutamate synthase. (1534 aa) |
| | MAE_29120 | succinyl-CoA synthetase alpha chain. (295 aa) |
| | MAE_29860 | succinyl-CoA synthetase beta chain. (394 aa) |
| | hemA | Transfer RNA-Gln reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (428 aa) |
| | MAE_30020 | Fructose-1,6-/sedoheptulose-1,7-bisphosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (345 aa) |
| | cysC | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (181 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (532 aa) |
| | fbaA | Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (359 aa) |
| | cysE-2 | Serine acetyltransferase. (252 aa) |
| | MAE_34870 | Putative phosphoketolase. (806 aa) |
| | MAE_34890 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (344 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa) |
| | MAE_36410 | NADH:flavin oxidoreductase. (366 aa) |
| | MAE_37250 | Hypothetical protein; Belongs to the HpcH/HpaI aldolase family. (260 aa) |
| | MAE_37350 | Aldo/keto reductase. (255 aa) |
| | MAE_38140 | Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. (1184 aa) |
| | MAE_38160 | Phosphofructokinase. (402 aa) |
| | prk | Phosphoribulokinase. (333 aa) |
| | hemL | Glutamate-1-semialdehyde aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (433 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1018 aa) |
| | MAE_39290 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (297 aa) |
| | hemB-2 | Porphobilinogen synthase; 5-aminolevulinate dehydratase; Belongs to the ALAD family. (328 aa) |
| | MAE_40040 | Putative hydrolase. (289 aa) |
| | MAE_41580 | Serine acetyltransferase. (213 aa) |
| | MAE_41860 | Glutamate decarboxylase. (185 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (319 aa) |
| | cysM | Cysteine synthase. (322 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (391 aa) |
| | zwf | Glucose 6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (402 aa) |
| | glcF | Glycolate oxidase Fe-S subunit. (451 aa) |
| | glcE | Glycolate oxidase subunit. (428 aa) |
| | cofH | FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (378 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (344 aa) |
| | thrA | Homoserine dehydrogenase. (432 aa) |
| | ureA | Urease gamma subunit; Belongs to the urease gamma subunit family. (100 aa) |
| | ureB | Urease beta subunit; Belongs to the urease beta subunit family. (108 aa) |
| | MAE_45610 | Heterodisulfide reductase subunit B. (301 aa) |
| | cysE-3 | Serine acetyltransferase. (205 aa) |
| | MAE_45950 | Amidase; Belongs to the amidase family. (465 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | MAE_47270 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (266 aa) |
| | rbcS | Ribulose bisphosphate carboxylase small subunit. (111 aa) |
| | rbcL | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. (471 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (205 aa) |
| | MAE_49340 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (888 aa) |
| | MAE_49470 | Uncharacterized zinc-type alcohol dehydrogenase-like protein. (334 aa) |
| | MAE_49560 | Aspartate kinase. (601 aa) |
| | phaB | PHA-specific acetoacetyl-CoA reductase. (238 aa) |
| | phaA | PHA-specific beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa) |
| | MAE_50450 | Dihydrolipoamide dehydrogenase. (485 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (525 aa) |
| | MAE_51650 | Putative thiosulfate sulfurtransferase precursor. (332 aa) |
| | cysK-2 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (315 aa) |
| | MAE_51820 | O-acetylhomoserine/O-acetylserine sulfhydrylase. (373 aa) |
| | MAE_52320 | Phosphoglucomutase. (544 aa) |
| | glcD | Glycolate oxidase subunit. (488 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (480 aa) |
| | pfkA | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (360 aa) |
| | narB | Ferredoxin-nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (730 aa) |
| | hemD | uroporphyrinogen-III C-methyltransferase and uroporphyrinogen-III synthase fusion protein; A fusion protein between CobA/CorA and HemD; gene:hemD or cobA. (505 aa) |
| | MAE_55440 | Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa) |
| | MAE_56250 | Succinate dehydrogenase flavoprotein subunit. (575 aa) |
| | accB | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (164 aa) |
| | accD | acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (316 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa) |
| | MAE_59020 | Thiosulfate sulfurtransferase. (274 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa) |
| | thrC | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (369 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa) |
| | MAE_59640 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase component; Component E2. (419 aa) |
| | cysK-3 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (319 aa) |
| | MAE_60960 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa) |
| | MAE_61240 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (869 aa) |
| | ureC | Urease alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (569 aa) |
| | rpe | Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (235 aa) |
| | icd | Isocitrate dehydrogenase (NADP+). (478 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | asd | Aspartate beta-semialdehyde dehydrogenese; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa) |
