STRINGSTRING
A9D14_07595 A9D14_07595 GCA_001661675_00001 GCA_001661675_00001 A9D14_00035 A9D14_00035 A9D14_00070 A9D14_00070 A9D14_00170 A9D14_00170 A9D14_00580 A9D14_00580 A9D14_00760 A9D14_00760 A9D14_00770 A9D14_00770 A9D14_00955 A9D14_00955 A9D14_00965 A9D14_00965 A9D14_01010 A9D14_01010 A9D14_01605 A9D14_01605 pckA pckA A9D14_02130 A9D14_02130 ilvD ilvD nnrE nnrE A9D14_02265 A9D14_02265 A9D14_02280 A9D14_02280 A9D14_02385 A9D14_02385 A9D14_02390 A9D14_02390 queE queE A9D14_02795 A9D14_02795 A9D14_02800 A9D14_02800 edd edd A9D14_02820 A9D14_02820 A9D14_02970 A9D14_02970 A9D14_03170 A9D14_03170 A9D14_03500 A9D14_03500 A9D14_03665 A9D14_03665 leuD leuD leuC leuC trpA trpA trpB trpB A9D14_04510 A9D14_04510 A9D14_04520 A9D14_04520 rlpA rlpA dapA dapA A9D14_05130 A9D14_05130 A9D14_05170 A9D14_05170 A9D14_05255 A9D14_05255 moaC moaC trpC trpC trpE trpE A9D14_05615 A9D14_05615 A9D14_05800 A9D14_05800 A9D14_05840 A9D14_05840 eno eno ribB ribB A9D14_06255 A9D14_06255 A9D14_06445 A9D14_06445 ispDF ispDF fumC fumC A9D14_07185 A9D14_07185 A9D14_07340 A9D14_07340 A9D14_07345 A9D14_07345 A9D14_07490 A9D14_07490 aroQ aroQ A9D14_07560 A9D14_07560 A9D14_07600 A9D14_07600 mltG mltG A9D14_08000 A9D14_08000 fabZ fabZ psd psd A9D14_08275 A9D14_08275 A9D14_08320 A9D14_08320 moaA moaA A9D14_09005 A9D14_09005 A9D14_09015 A9D14_09015 A9D14_09095 A9D14_09095 lysA lysA argH argH hisF hisF hisH hisH hisB hisB thiC thiC tal tal A9D14_09485 A9D14_09485 aroB aroB A9D14_10250 A9D14_10250 A9D14_10490 A9D14_10490 A9D14_10565 A9D14_10565 A9D14_10760 A9D14_10760 A9D14_10765 A9D14_10765 A9D14_11620 A9D14_11620 A9D14_12005 A9D14_12005 nth nth hemH hemH A9D14_12890 A9D14_12890 rlpA-2 rlpA-2 A9D14_13415 A9D14_13415 A9D14_13515 A9D14_13515 hemE hemE purK purK purE purE mutM mutM A9D14_14260 A9D14_14260 A9D14_14295 A9D14_14295 GCA_001661675_02873 GCA_001661675_02873 hutU hutU hutH hutH A9D14_15020 A9D14_15020 A9D14_15040 A9D14_15040 ribB-2 ribB-2 cobD cobD A9D14_15270 A9D14_15270 A9D14_15720 A9D14_15720 A9D14_15760 A9D14_15760 A9D14_15800 A9D14_15800 A9D14_15820 A9D14_15820 A9D14_15905 A9D14_15905 A9D14_16000 A9D14_16000 A9D14_16010 A9D14_16010 A9D14_16035 A9D14_16035 A9D14_16065 A9D14_16065 A9D14_16155 A9D14_16155 A9D14_16200 A9D14_16200 A9D14_16310 A9D14_16310 A9D14_16355 A9D14_16355 A9D14_16370 A9D14_16370 A9D14_16575 A9D14_16575 psd-2 psd-2 A9D14_16800 A9D14_16800 A9D14_16960 A9D14_16960 A9D14_17085 A9D14_17085 A9D14_17190 A9D14_17190 A9D14_17235 A9D14_17235 A9D14_17760 A9D14_17760 eno-2 eno-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A9D14_07595Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
GCA_001661675_00001Unannotated protein. (122 aa)
A9D14_00035Unannotated protein. (304 aa)
A9D14_00070Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (893 aa)
A9D14_00170Unannotated protein. (336 aa)
A9D14_00580Unannotated protein. (213 aa)
A9D14_00760Unannotated protein. (523 aa)
A9D14_00770Unannotated protein. (235 aa)
A9D14_00955Unannotated protein. (260 aa)
A9D14_00965Unannotated protein; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (342 aa)
A9D14_01010Unannotated protein. (646 aa)
A9D14_01605Unannotated protein. (217 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa)
A9D14_02130Unannotated protein; Belongs to the DNA photolyase family. (461 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (618 aa)
nnrEUnannotated protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (478 aa)
A9D14_02265Unannotated protein; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily. (389 aa)
A9D14_02280Unannotated protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (413 aa)
A9D14_02385Unannotated protein. (145 aa)
A9D14_02390Unannotated protein. (259 aa)
queEUnannotated protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (248 aa)
A9D14_02795Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (929 aa)
A9D14_02800Unannotated protein. (210 aa)
eddUnannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa)
A9D14_02820Unannotated protein. (138 aa)
A9D14_02970Unannotated protein. (382 aa)
A9D14_03170Unannotated protein. (531 aa)
A9D14_03500Unannotated protein. (141 aa)
A9D14_03665Unannotated protein. (290 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (483 aa)
trpAUnannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
trpBUnannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (420 aa)
A9D14_04510Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). (224 aa)
A9D14_04520Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (436 aa)
rlpAUnannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (184 aa)
dapAUnannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
A9D14_05130Unannotated protein. (296 aa)
A9D14_05170Unannotated protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (407 aa)
A9D14_05255Unannotated protein. (134 aa)
moaCUnannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (164 aa)
trpCUnannotated protein; Belongs to the TrpC family. (279 aa)
trpEUnannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (516 aa)
A9D14_05615Unannotated protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (227 aa)
A9D14_05800Unannotated protein. (210 aa)
A9D14_05840Unannotated protein; Belongs to the IlvD/Edd family. (598 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ribBUnannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (438 aa)
A9D14_06255Unannotated protein. (771 aa)
A9D14_06445Unannotated protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (215 aa)
ispDFUnannotated protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (411 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
A9D14_07185Unannotated protein; Belongs to the IlvD/Edd family. (590 aa)
A9D14_07340Unannotated protein. (467 aa)
A9D14_07345Unannotated protein; Belongs to the EutC family. (249 aa)
A9D14_07490Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (233 aa)
aroQUnannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (160 aa)
A9D14_07560Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (678 aa)
A9D14_07600Unannotated protein. (351 aa)
mltGUnannotated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (324 aa)
A9D14_08000Unannotated protein. (328 aa)
fabZUnannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (152 aa)
psdUnannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (253 aa)
A9D14_08275Unannotated protein. (315 aa)
A9D14_08320Unannotated protein. (1195 aa)
moaAUnannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (339 aa)
A9D14_09005Unannotated protein. (123 aa)
A9D14_09015Unannotated protein. (471 aa)
A9D14_09095Unannotated protein. (259 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa)
argHUnannotated protein. (464 aa)
hisFUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa)
hisHUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa)
hisBUnannotated protein. (208 aa)
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa)
talUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
A9D14_09485Unannotated protein. (522 aa)
aroBUnannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (370 aa)
A9D14_10250Unannotated protein. (154 aa)
A9D14_10490Unannotated protein. (95 aa)
A9D14_10565Unannotated protein. (418 aa)
A9D14_10760Unannotated protein. (125 aa)
A9D14_10765Unannotated protein. (134 aa)
A9D14_11620Unannotated protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (353 aa)
A9D14_12005Unannotated protein. (220 aa)
nthUnannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (225 aa)
hemHUnannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (353 aa)
A9D14_12890Unannotated protein. (651 aa)
rlpA-2Unannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (207 aa)
A9D14_13415Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa)
A9D14_13515Unannotated protein; Belongs to the ALAD family. (329 aa)
hemEUnannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa)
purKUnannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (371 aa)
purEUnannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa)
mutMUnannotated protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa)
A9D14_14260Unannotated protein. (422 aa)
A9D14_14295Unannotated protein. (383 aa)
GCA_001661675_02873Unannotated protein. (99 aa)
hutUUnannotated protein; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)
hutHUnannotated protein. (509 aa)
A9D14_15020Unannotated protein. (290 aa)
A9D14_15040Unannotated protein. (716 aa)
ribB-2Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (368 aa)
cobDUnannotated protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa)
A9D14_15270Unannotated protein. (330 aa)
A9D14_15720Unannotated protein. (261 aa)
A9D14_15760Unannotated protein. (448 aa)
A9D14_15800Unannotated protein. (265 aa)
A9D14_15820Unannotated protein. (494 aa)
A9D14_15905Unannotated protein. (402 aa)
A9D14_16000Unannotated protein. (291 aa)
A9D14_16010Unannotated protein. (433 aa)
A9D14_16035Unannotated protein. (279 aa)
A9D14_16065Unannotated protein. (456 aa)
A9D14_16155Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (684 aa)
A9D14_16200Unannotated protein. (392 aa)
A9D14_16310Unannotated protein. (153 aa)
A9D14_16355Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
A9D14_16370Unannotated protein. (121 aa)
A9D14_16575Unannotated protein. (135 aa)
psd-2Unannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (285 aa)
A9D14_16800Unannotated protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (265 aa)
A9D14_16960Unannotated protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (421 aa)
A9D14_17085Unannotated protein; Belongs to the enoyl-CoA hydratase/isomerase family. (695 aa)
A9D14_17190Unannotated protein. (130 aa)
A9D14_17235Unannotated protein. (341 aa)
A9D14_17760Unannotated protein. (302 aa)
eno-2Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
Your Current Organism:
Croceicoccus marinus
NCBI taxonomy Id: 450378
Other names: CGMCC 1.6776, Croceicoccus marinus Xu et al. 2009 emend. Huang et al. 2015, JCM 14846, Sphingomonadaceae bacterium E4A9, strain E4A9
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